Bound Iron and Unsaturated Iron-binding Capacity of Serum; Rapid and Reliable Quantitative Determination

1954 ◽  
Vol 87 (2) ◽  
pp. 443-448 ◽  
Author(s):  
A. L. Schade ◽  
J. Oyama ◽  
R. W. Reinhart ◽  
J. R. Miller
The Lancet ◽  
1975 ◽  
Vol 305 (7919) ◽  
pp. 1293
Author(s):  
Terry Hamblin

1966 ◽  
Vol 4 (3) ◽  
pp. 9-11

We have discussed iron preparations for adults in earlier articles;1 much of the information applies equally to children. Iron is not a ‘tonic’ and should be given only to prevent or correct iron deficiency. Estimation of the haemoglobin and inspection of a blood smear are the minimum investigations necessary before iron is prescribed in therapy. When deficiency is suspected in the absence of hypochromic anaemia, plasma iron and iron-binding capacity should be estimated and/or the bone marrow examined for haemosiderin crystals which disappear when iron stores are depleted.


1984 ◽  
Vol 21 (6) ◽  
pp. 597-600 ◽  
Author(s):  
J. E. Smith ◽  
K. Moore ◽  
D. Boyington ◽  
D. S. Pollmann ◽  
D. Schoneweis

2011 ◽  
Vol 412 (23-24) ◽  
pp. 2261-2266 ◽  
Author(s):  
Katsuya Ikuta ◽  
Satoshi Ito ◽  
Hiroki Tanaka ◽  
Katsunori Sasaki ◽  
Yoshihiro Torimoto ◽  
...  

Blood ◽  
1967 ◽  
Vol 30 (4) ◽  
pp. 417-424 ◽  
Author(s):  
R. A. FAWWAZ ◽  
H. S. WINCHELL ◽  
M. POLLYCOVE ◽  
T. SARGENT

Abstract In patients with spontaneous chronic low plasma latent iron-binding capacity, a large fraction of the intestinally absorbed iron is deposited in the liver without prior appearance in the systemic plasma. Such hepatic iron is not released to any large extent during the subsequent 2 weeks. Our results are consistent with the hypothesis that iron absorbed from the intestinal tract is not initially bound to transferrin. When the plasma latent iron-binding capacity is normal, iron binds to transferrin prior to reaching the liver; when the plasma latent iron-binding capacity is low, a portion of the iron reaches the liver either unbound or abnormally bound to transferrin, resulting in its immediate hepatic deposition.


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