To Evaluate the Effect of Estrogen Receptor Alpha (ER- a) Variant in Conjunction With Vitamin D Among PostMenopausal Women

2021 ◽  
Vol 13 (02) ◽  
Keyword(s):  
Vitamin D ◽  
Estrogen Receptor ◽  
Postmenopausal Women ◽  
Estrogen Receptor Alpha ◽  
Receptor Alpha

scholarly journals Vitamin D receptor and Estrogen receptor alpha Genotype affects Exercise related Bone mass in Japanese healthy women

2013 ◽  
Vol 27 (S1) ◽  
Author(s):  
Hiroyo Kondo ◽  
Hidemi Fujino ◽  
Shinichiro Murakami ◽  
Naoto Fujita ◽  
Fumiko Nagatomo ◽  
...  
Keyword(s):  
Vitamin D ◽  
Estrogen Receptor ◽  
Bone Mass ◽  
Vitamin D Receptor ◽  
Estrogen Receptor Alpha ◽  
Receptor Alpha ◽  
Healthy Women

P3-326: ESTROGEN RECEPTOR-ALPHA GENE (ESR1) POLYMORPHISMS AND COGNITIVE FUNCTIONS IN POSTMENOPAUSAL WOMEN

2006 ◽  
Vol 14 (7S_Part_23) ◽  
pp. P1205-P1206
Author(s):  
Kasia Gustaw Rothenberg ◽  
Dorota Raczkiewicz ◽  
Jaroslaw Pinkas ◽  
Iwona Bojar
Keyword(s):  
Estrogen Receptor ◽  
Postmenopausal Women ◽  
Cognitive Functions ◽  
Estrogen Receptor Alpha ◽  
Receptor Alpha ◽  
Estrogen Receptor Alpha Gene ◽  
Alpha Gene

scholarly journals Estrogen receptor alpha gene polymorphisms are associated with estradiol levels in postmenopausal women

2005 ◽  
Vol 153 (2) ◽  
pp. 327-334 ◽  
Author(s):  
Stephanie C E Schuit ◽  
Frank H de Jong ◽  
Lisette Stolk ◽  
W Nadia H Koek ◽  
Joyce B J van Meurs ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Postmenopausal Women ◽  
Estrogen Receptor Alpha ◽  
Plasma Concentrations ◽  
Dehydroepiandrosterone Sulfate ◽  
Population Based ◽  
Plasma Testosterone ◽  
Receptor Alpha ◽  
Estrogen Receptor Alpha Gene ◽  
Haplotype 1

Objective: Postmenopausal estradiol (E2) levels vary widely between individuals and this variation is an important determinant of diseases such as osteoporosis. It has been suggested that the estrogen receptor alpha (ESR1) gene may influence peripheral E2 levels, but the role of common sequence variations in the ESR1 gene is unclear. Methods: In 631 postmenopausal women and 528 men from the Rotterdam Study, a population-based, prospective cohort study of individuals aged 55 years and over, ESR1 PvuII-XbaI haplotypes were determined and correlated with plasma E2 levels. Results: In women, haplotype 1 (T-A) was significantly associated with an allele-dose-dependent decrease in E2. After adjusting for age, body mass index, years since menopause and testosterone levels, plasma E2 levels decreased by 1.90 pmol/l per allele copy of this haplotype (P < 0.05). Extreme genotypes, representing 23 and 27% of the population, varied by 3.93 pmol/l. No association with plasma testosterone was observed. In a subset of 446 women, no association of genotype with plasma concentrations of dehydroepiandrosterone sulfate, androstenedione or estrone was seen. In men, none of the sex hormone levels was associated with the ESR1 PvuII-XbaI haplotypes. Conclusion: We have demonstrated a role for genetic variations in the ESR1 gene in determining post-menopausal E2 levels in women.

Estrogen receptor alpha and risk for cognitive impairment in postmenopausal women

2006 ◽  
Vol 16 (2) ◽  
pp. 85-88 ◽  
Author(s):  
Line Olsen ◽  
Henrik B. Rasmussen ◽  
Thomas Hansen ◽  
Yu Z. Bagger ◽  
L??szl?? B. Tank?? ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Cognitive Impairment ◽  
Postmenopausal Women ◽  
Estrogen Receptor Alpha ◽  
Receptor Alpha

Prevalence of vitamin D receptor BsmI, estrogen receptor alpha PvuII and COL1A1 Sp1 polymorphisms in elderly Spanish population with hip fracture. Preliminary results

Bone ◽  
2012 ◽  
Vol 50 ◽  
pp. S108
Author(s):  
J.M. Moran⁎ ◽  
J.M. Lavado-Garcia ◽  
M.L. Canal-Macias ◽  
M.C. Costa-Fernandez ◽  
J.F. Calderon-Garcia ◽  
...  
Keyword(s):  
Vitamin D ◽  
Estrogen Receptor ◽  
Hip Fracture ◽  
Vitamin D Receptor ◽  
Estrogen Receptor Alpha ◽  
Spanish Population ◽  
Receptor Alpha ◽  
Preliminary Results
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