scholarly journals Review on Simultaneous Determination of Antihypertensive Analytes in Pharmaceutical Dosage Form by Different Analytical Methods

2019 ◽  
Vol 2 (1) ◽  
Keyword(s):  
Simultaneous Determination ◽  
Analytical Methods ◽  
Dosage Form ◽  
Pharmaceutical Dosage Form

SIMULTANEOUS DETERMINATION OF PRAMOCAINE HCL AND HYDROCORTISONE ACETATE IN PHARMACEUTICAL DOSAGE FORM

2013 ◽  
Vol 36 (19) ◽  
pp. 2774-2784 ◽  
Author(s):  
Hanan A. Merey ◽  
Mohammed A. Mohammed ◽  
Fahima A. Morsy ◽  
Maissa Y. Salem
Keyword(s):  
Simultaneous Determination ◽  
Dosage Form ◽  
Hydrocortisone Acetate ◽  
Pharmaceutical Dosage Form

Simultaneous determination of Sulphadoxine and Pyrimethamine by taking Tolterodine as an internal standard in Pharmaceutical dosage form by RP-HPLC

2021 ◽  
pp. 145-150
Author(s):  
Sushil D. Patil ◽  
Pravin B. Shelke ◽  
Priti Aher ◽  
Maswood Ahmed Hafizur Rahman
Keyword(s):  
Simultaneous Determination ◽  
Dosage Form ◽  
Internal Standard ◽  
Hplc Method ◽  
Control Analysis ◽  
Pharmaceutical Dosage Form ◽  
Quality Control Analysis ◽  
Rp Hplc ◽  
Sulphadoxine Pyrimethamine

A simple, rapid, economic, sensitive and precise HPLC method has been developed for the simultaneous determination of Sulphadoxine and Pyrimethamine in pharmaceutical dosage form by taking Tolterodine as an internal standard. The method was carried out using Phenomenex C18 (4.6ID × 250mm; 5µm) column and mobile phase comprised of methanol and Phosphate Buffer in proportion of ratio 60:40 v/v. The flow rate was 1.0mL/min and detection was carried out at 276nm. The retention time of Sulphadoxine, Pyrimethamine and Tolterodine were found to be 2.967, 4.058 and 6.908 respectively. Linearity of Sulphadoxine and Pyrimethamine in the range of 2 to 12μg/mL and 4 to 24μg/mL respectively. The % recoveries of Sulphadoxine and Pyrimethamine were found to be in between 99.93% to 99. 96 % respectively. The proposed method is suitable for the routine quality control analysis for simultaneous determination of Sulphadoxine and Pyrimethamine was in bulk and pharmaceutical dosage form.

Simultaneous Determination of Timolol maleate and Brimonidine tartarate in their Pharmaceutical Dosage Form

2014 ◽  
Vol 4 (2) ◽  
pp. 132-145 ◽  
Author(s):  
Mohamed S. Rizk ◽  
Hanan A. Merey ◽  
Shereen M. Tawakkol ◽  
Mona N. Sweilam
Keyword(s):  
Simultaneous Determination ◽  
Dosage Form ◽  
Timolol Maleate ◽  
Pharmaceutical Dosage Form
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