scholarly journals Autologous Fat Grafting in Management of Patients with Progressive Hemifacial Atrophy

2016 ◽  
Vol 2 (1) ◽  
pp. 66-70
Author(s):  
Jainath Reddappa ◽  

Background: Progressive hemi facial atrophy or Romberg disease is a rare neurocutaneous syndrome characterized by slow progressive atrophy on one side of face involving skin, subcutaneous and connective tissue. Various methods have been described for soft tissue augmentation in patients with progressive hemi facial atrophy. Autologous fat, dermofat, fascial grafts have been used for grade 1,2 and 3 atrophy. Free flaps, cartilage and bone grafts are described for grade 3 and 4 atrophy. Aims and objectives: To study efficacy of autologous fat graft in patients with grade 1, 2 and 3 hemi facial atrophy. Strategies to reduce fat absorption and to calculate approximate amount of fat required required by facial mask template. Observations: It is a prospective study conducted in Department of plastic surgery, Bangalore Medical college and Research Institute, Bangalore in 10 patients with grade 2 and 3 Progressive hemi facial atrophy. All patients with stable non-progressive atrophy were graded for severity of disease and face-mask templates were prepared by pro-sthodontists to know approximate amount of fat required for injection. Fat was aspirated by low-pressure small suction cannulas manually and infiltrated at multiple points and in multiple planes after sedimentation and separation of fat. Five of the patients with grade 2 and 3 of patients with grade 3 atrophy were satisfied with symmetric face and with emotional betterment. Two patients needed repeat fat grafting after 2 years of follow-up. Conclusion: Autologous fat grafting is a simple and safe method for augmentation of soft tissue in patients with grade 1, 2 and 3 Progressive hemi facial atrophy. Aspiration of fat with low-pressure small cannulas and infiltrating in multiple planes improves fat survival. Preparing face-mask templates gives an idea of approximate volume of fat required. Keywords: Progressive hemifacial atrophy, Autologous fat grafting, Face-mask templates, Strategies for decreased fat absorption.

2019 ◽  
Vol 40 (3) ◽  
pp. NP103-NP105
Author(s):  
Faith H K Jeon ◽  
Keerthusan Koneswaran ◽  
Jajini Varghese ◽  
Michelle Griffin ◽  
Carole Frosdick ◽  
...  

Author(s):  
◽  

Aim: Frontal linear scleroderma, also known as ‘‘en coup de sabre,’’ is a congenital deformity characterized by atrophy and furrowing of the skin of the front parietal area above the level of the eyebrows. In most cases it occurs as a single paramedian line that may be associated with hypoplasia of underlying structures and facial hemiatrophy. In case of a wide lesion many reconstructive strategies have been proposed. The modern approach is aimed at augmentation of the tissue deficiency by using lipostructure and tissue regeneration. Autologous fat transfer (AFT) seems to be an effective strategy to restore the normal volume and contour of the face while providing a source of adipose-derived stem cells (ADSCs) with a multilineage differentiation potential. Methods: In this report, we present a rare case of linear scleroderma en coupe de sabre which was successfully managed with three stages of autologous fat grafting. Conclusion: The proposed uses for ADSCs in tissue repair and regeneration are quite impressive. Recent works on ADSCs would suggest that adult cells may prove to be an equally powerful regenerative tool in treating congenital and acquired maxillofacial disorders. More importantly, physicians, researchers and international associations need to cooperate in informing clinicians about what practices are based on evidence and to encourage support of additional research. There is increasing interest in a possible therapeutic effect of ADSCs from processed lipoaspirate for a wide spectrum of clinical applications in the facial and craniofacial area. AFT can be used in any facial area where soft tissue is lacking or where there is scarring, producing natural and long-lasting results. Mesenchymal stem cells represent a great tool in regenerative medicine. However, more definitive studies are needed to answer specific questions regarding the best technique to be used and the role of ADSCs. Autologous fat grafting provides a safe and easy approach for the treatment of linear scleroderma en coup de sabre, long-term clinically satisfactory results can be obtained.


2014 ◽  
Vol 2 (3) ◽  
pp. e123 ◽  
Author(s):  
Robert C. Wu ◽  
Ian Maxwell ◽  
Ilun Yang ◽  
Mario B. Jarmuske ◽  
Robin P. Boushey

2019 ◽  
Vol 7 (11) ◽  
pp. e2518 ◽  
Author(s):  
Angelo Trivisonno ◽  
Dania Nachira ◽  
Ivo Boškoski ◽  
Filippo Calcagni ◽  
Andrea Tringali ◽  
...  

2019 ◽  
Vol 7 (5) ◽  
pp. e2196 ◽  
Author(s):  
O Teresa Minjung ◽  
Kimberly Chan ◽  
Tara Brennan ◽  
Dylan Roden ◽  
David Shamouelian ◽  
...  

2021 ◽  
pp. 42-44
Author(s):  
Vikesh Vij ◽  
Sunil Srivastava

INTRODUCTION: Facial scars cause aesthetic impairment and functional limitation for the patient. Till date there is no gold standard treatment for facial scar tissue. Autologous fat grafting has shown promising results for depressed scar tissue and soft tissue volume deciency seen in certain congenital syndromes. METHODS AND MATERIAL: 14 patients (11 female and 3 male) with depressed scars and syndromic facial volume deciencies were treated with autologous fat grafting. A visual 4-grade scale was used for the evaluation of the results. RESULTS: All patients showed improvement. 12 patients required single operation whereas 2 patients required another operation. The patients were followed up till 18 months. CONCLUSION : Autologous fat grafting is a great method to address the problems of volume deciency and depressed scars on the face. Its use as a natural soft tissue ller are long lasting.


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