scholarly journals Gastro-esophageal reflux disease and Barrett’s esophagus: an overview with an histologic diagnostic approach

Pathologica ◽  
2020 ◽  
Vol 112 (3) ◽  
pp. 117-127
Author(s):  
Luca Mastracci
Keyword(s):  
Barrett’S Esophagus ◽  
Reflux Disease ◽  
Barrett's Esophagus ◽  
Diagnostic Approach ◽  
Esophageal Reflux

scholarly journals Gastro-Esophageal Reflux Disease Symptoms and Demographic Factors as a Pre-Screening Tool for Barrett’s Esophagus

PLoS ONE ◽  
2014 ◽  
Vol 9 (4) ◽  
pp. e94163 ◽  
Author(s):  
Xinxue Liu ◽  
Angela Wong ◽  
Sudarshan R. Kadri ◽  
Andrej Corovic ◽  
Maria O’Donovan ◽  
...  
Keyword(s):  
Barrett’S Esophagus ◽  
Reflux Disease ◽  
Barrett's Esophagus ◽  
Screening Tool ◽  
Demographic Factors ◽  
Esophageal Reflux ◽  
Disease Symptoms

Duodeno-gastro(-esophageal) reflux in reflux disease and in Barrett's esophagus

1998 ◽  
Vol 114 ◽  
pp. A295
Author(s):  
J.W.A. Straathof ◽  
S. Farsi ◽  
C.B.H.W. Lamers ◽  
A.A.M. Masclee
Keyword(s):  
Barrett’S Esophagus ◽  
Reflux Disease ◽  
Barrett's Esophagus ◽  
Esophageal Reflux

Barrett's esophagus in women, a manifestation of severe gastroesophageal reflux disease

2001 ◽  
Vol 120 (5) ◽  
pp. A410-A410
Author(s):  
F BANKI ◽  
S DEMEESTER ◽  
R MASON ◽  
G CAMPOS ◽  
C STREETS ◽  
...  
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Barrett’S Esophagus ◽  
Reflux Disease ◽  
Barrett's Esophagus

scholarly journals Cancer Prevention in Patients with GERD and Barrett’s Esophagus—Medicine

2021 ◽  
Vol 1 (1) ◽  
pp. 50-62
Author(s):  
Carmelo Scarpignato ◽  
David H. Wang
Keyword(s):  
Risk Factors ◽  
Reactive Oxygen Species ◽  
Cell Proliferation ◽  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Acid Reflux ◽  
Oxygen Species ◽  
Esophageal Reflux ◽  
Early Disease ◽  
Chemopreventive Agents

Gastro-esophageal reflux disease (GERD) and Barrett’s esophagus are risk factors for esophageal adenocarcinoma (EAC). Chemoprevention is an attractive strategy, more effective than identifying early disease. Since acid reflux can lead to increased cell proliferation, decreased apoptosis, production of reactive oxygen species, DNA damage, and esophageal production of proinflammatory and pro-proliferative cytokines, proton pump inhibitors (PPIs) alone, or in combination with COX-inhibition, are the most suitable chemopreventive agents. Other compounds (statins, metformin, and selected nutraceuticals) cannot currently be recommended. Data are strong enough to warrant PPI treatment of virtually all patients with Barrett’s esophagus, although the best regimen has not yet been defined.

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