Theoretical analysis of flow properties of aggregating red cell suspensions in narrow horizontal tubes

1994 ◽  
Vol 14 (4) ◽  
pp. 519-530
Author(s):  
Tadayoshi Murata
Keyword(s):  
Theoretical Analysis ◽  
Cell Suspensions ◽  
Red Cell ◽  
Flow Properties ◽  
Horizontal Tubes

Influence of fibrinogen on flow properties of erythrocyte suspensions

1964 ◽  
Vol 207 (5) ◽  
pp. 1035-1040 ◽  
Author(s):  
Roe E. Wells ◽  
Thomas H. Gawronski ◽  
Paul J. Cox ◽  
Richard D. Perera
Keyword(s):  
Shear Stress ◽  
Shear Rate ◽  
Cell Aggregation ◽  
Cell Suspensions ◽  
Fibrinogen Concentration ◽  
Sedimentation Rates ◽  
Cell Aggregates ◽  
Red Cell ◽  
Flow Properties ◽  
Yield Value

The influence of fibrinogen on the flow properties of red cell suspensions (hematocrit 41) was studied by viscometry at low rates of shear (0.1–20 sec–1). These findings were correlated with sedimentation rates and photomicrographical studies of cell aggregation. Fibrinogen concentration was varied from 0.3 to 2.0 g/100 ml. The viscosity of the pure solutions of fibrinogen was independent of shear rate, ranging from 0.87 to 1.7 centipoise (cp) at 37 C. The viscosity of the cell suspensions at 10 sec–1 varied from 4.3 cp in 0.3 g/100 ml fibrinogen to 14 cp in 2 g/100 ml fibrinogen. All suspensions were markedly dependent on shear rate, viscosity increasing in exponential-like fashion as shear rate decreased. Extrapolation of plots of shear stress1/2 versus shear rate1/2 revealed the suspensions to sustain a finite stress without deformation or flow, the "yield value" increasing as fibrinogen concentration increased. Photomicrographs of dilute cell suspensions revealed the formation of cell aggregates and rouleaux, increasing in size and descent velocity as fibrinogen concentration increased.

Red cell deformation and fluidity of concentrated cell suspensions.

1969 ◽  
Vol 27 (2) ◽  
pp. 213-217 ◽  
Author(s):  
R Wells ◽  
H Schmid-Schönbein
Keyword(s):  
Cell Suspensions ◽  
Cell Deformation ◽  
Red Cell

Photoinactivation of Leishmania donovani infantum in red cell suspensions by a flexible thiopyrylium sensitizer

Vox Sanguinis ◽  
2006 ◽  
Vol 91 (2) ◽  
pp. 178-180 ◽  
Author(s):  
S. J. Wagner ◽  
A. Skripchenko ◽  
J. Salata ◽  
L. J. Cardo
Keyword(s):  
Leishmania Donovani ◽  
Cell Suspensions ◽  
Red Cell

Rheology and structure of blood suspensions

1964 ◽  
Vol 19 (1) ◽  
pp. 127-133 ◽  
Author(s):  
S. E. Charm ◽  
W. McComis ◽  
G. Kurland
Keyword(s):  
Shear Stress ◽  
Shear Rate ◽  
Yield Stress ◽  
Structural Model ◽  
Cell Suspensions ◽  
Rate Curve ◽  
Red Cell ◽  
Shear Rates ◽  
Straight Line ◽  
Rate Plot

A structural model developed for kaolin suspensions was applied to blood in order to determine the structure and strength of the red cell suspensions. The yield stress of red cell suspensions determined in settling experiments agreed with the yield stress determined from shear stress-shear rate information employing Casson's equation. Theoretical considerations indicate that the shear stress-shear rate curve for blood should approach a straight line. This was found to be true at shear rates above 40 sec-1. The slope of this line was predicted from calculations based on sedimentation experiments and a modified Einstein's equation. The data suggest that the curvature of the shear stress-shear rate plot at low shear rates is due to aggregates of cells which break down under increasing shear rate, resulting finally in individual flocs. It is suggested that a floc consists of one to four cells with adhering plasma. The aggregate was calculated to have twice as much plasma associated with it as does a floc. However, the size of the aggregate could not be determined since the number of flocs associated with an aggregate could not be determined. shear stress-shear rate curve; red cell floc; red cell aggregate; sedimentation rate; blood viscosity and flow Submitted on February 28, 1963

Relation between paper filterability and viscosity of normal and abnormal red cell suspensions

2016 ◽  
Vol 1 (4) ◽  
pp. 341-347
Author(s):  
M. Stäubli ◽  
P. Schläppi ◽  
P.W. Straub
Keyword(s):  
Cell Suspensions ◽  
Red Cell

Mechanism of hemolysis after intravenous glycerol administration

1960 ◽  
Vol 198 (4) ◽  
pp. 895-898 ◽  
Author(s):  
Gabriel G. Pinter ◽  
D. B. Zilversmit
Keyword(s):  
Intravenous Injection ◽  
Rapid Decrease ◽  
Cell Suspensions ◽  
Glycerol Concentration ◽  
Red Cell ◽  
In Vitro Experiments ◽  
Intravascular Hemolysis ◽  
Hemolytic Effect ◽  
Similar Solutions

Concentrated glycerol solutions in 0.9% saline, when administered intravenously to rabbits and rats, caused considerable intravascular hemolysis, but similar solutions given to dogs had no hemolytic effect. Perfusion of the partially isolated hind leg of the rabbit with Cr51-tagged and glycerol-containing red cell suspensions showed hemolysis of only those cells containing glycerol. This observation eliminates a hemolysin as the cause for the hemolysis. In vitro experiments showed that glycerol penetrates the erythrocytes of rats, rabbits and man quite rapidly, whereas the cells of dogs were penetrated at a much slower rate. It is suggested that the intravascular hemolysis caused by intravenous glycerol is produced by the rapid uptake of glycerol by the erythrocytes and a subsequent osmotic imbalance caused by the rapid decrease of glycerol concentration in the circulating plasma. It is proposed that this mechanism is a general one and explains, for example, the intravascular hemolysis caused by the intravenous injection of hyperosmotic urea dissolved in 0.9% saline.

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