Solar Radiation-Related Malignant Neoplasm

2020 ◽  
Author(s):  
Space Weather ◽  
2006 ◽  
Vol 4 (6) ◽  
pp. n/a-n/a ◽  
Author(s):  
Tracy Staedter
Keyword(s):  

2003 ◽  
Vol 107 ◽  
pp. 743-747
Author(s):  
D. R.S. Lean ◽  
SD. Siciliano
Keyword(s):  

2019 ◽  
pp. 53-65
Author(s):  
Renata Domingos ◽  
Emeli Guarda ◽  
Elaise Gabriel ◽  
João Sanches

In the last decades, many studies have shown ample evidence that the existence of trees and vegetation around buildings can contribute to reduce the demand for energy by cooling and heating. The use of green areas in the urban environment as an effective strategy in reducing the cooling load of buildings has attracted much attention, though there is a lack of quantitative actions to apply the general idea to a specific building or location. Due to the large-scale construction of high buildings, large amounts of solar radiation are reflected and stored in the canyons of the streets. This causes higher air temperature and surface temperature in city areas compared to the rural environment and, consequently, deteriorates the urban heat island effect. The constant high temperatures lead to more air conditioning demand time, which results in a significant increase in building energy consumption. In general, the shade of the trees reduces the building energy demand for air conditioning, reducing solar radiation on the walls and roofs. The increase of urban green spaces has been extensively accepted as effective in mitigating the effects of heat island and reducing energy use in buildings. However, by influencing temperatures, especially extreme, it is likely that trees also affect human health, an important economic variable of interest. Since human behavior has a major influence on maintaining environmental quality, today's urban problems such as air and water pollution, floods, excessive noise, cause serious damage to the physical and mental health of the population. By minimizing these problems, vegetation (especially trees) is generally known to provide a range of ecosystem services such as rainwater reduction, air pollution mitigation, noise reduction, etc. This study focuses on the functions of temperature regulation, improvement of external thermal comfort and cooling energy reduction, so it aims to evaluate the influence of trees on the energy consumption of a house in the mid-western Brazil, located at latitude 15 ° S, in the center of South America. The methodology adopted was computer simulation, analyzing two scenarios that deal with issues such as the influence of vegetation and tree shade on the energy consumption of a building. In this way, the methodological procedures were divided into three stages: climatic contextualization of the study region; definition of a basic dwelling, of the thermophysical properties; computational simulation for quantification of energy consumption for the four facade orientations. The results show that the façades orientated to north, east and south, without the insertion of arboreal shading, obtained higher values of annual energy consumption. With the adoption of shading, the facades obtained a consumption reduction of around 7,4%. It is concluded that shading vegetation can bring significant climatic contribution to the interior of built environments and, consequently, reduction in energy consumption, promoting improvements in the thermal comfort conditions of users.


2013 ◽  
Vol 40 (2) ◽  
Author(s):  
Asti Kristianti ◽  
Teti Madiadipoera ◽  
Bogi Soeseno

Background: Chemotherapy is worldwide used nowadays, and its toxicity still remain a problemespecially toxicity to the ear (ototoxicity). Cisplatin (cis-diamminedichloroplatinum) is one of themost commonly used chemotherapy and highly potent in treating epithelial malignancies. Ototoxicitycaused by cisplatin is irreversible, progressive, bilateral, sensorineural hearing loss especially on highfrequency (4-8 KHz) accompanied by tinnitus. Purpose: To observe the cochlear outer hair cells damagein malignancies patients treated with cisplatin. Methods: This study is an observational analytic studywith prospective design to determine the influence of high dose cisplatin on cochlear outer hair cellsfunction. The research was carried out at the ENT-HNS Department, Hasan Sadikin General HospitalBandung, from November 2007 until June 2008. Audiometry, tympanometry, and distortion productotoacoustic emission (DPOAE) examinations were conducted before chemotherapy and DPOAE, andtimpanometry was again measured three days after first and second cycles of cisplatin administration. McNemar test was performed to calculate the effects of high-dose cisplatin to the cochlear outer haircells function. To compare pre and post-cisplatin on alteration of cochlear hair cells function, Wilcoxontest was used. Results: In this study 60 ears from 30 subjects that meet the inclusion criteria, consistedof 25 man (83.3%) and 5 women (16.7%). The prevalence of damaged cochlear outer hair cells were63% at first cycle and 70% at second cycle of cisplatin administration. The decline of cochlear outerhair cells function was significant (p<0.001). Conclusion: High-dose cisplatin decreases cochlear outerhair cells function in patients with malignant neoplasm. Abstrak : Latar belakang: Kemoterapi sekarang rutin digunakan secara klinis di seluruh dunia. Sejalan denganhal tersebut toksisitas kemoterapi, khususnya terhadap telinga saat ini menjadi perhatian. Sisplatin(cis-diamminedichloroplatinum) adalah salah satu obat kemoterapi yang paling banyak digunakandan paling manjur untuk terapi keganasan epitelial. Efek ototoksik sisplatin yaitu terjadi gangguandengar sensorineural yang irreversible, progresif, bilateral pada frekuensi tinggi (4-8 kHz), dan disertaidengan tinitus. Tujuan: Untuk menilai penurunan fungsi sel rambut luar koklea pada penderita tumorganas sesudah pemberian sisplatin dosis tinggi dengan menggunakan DPOAE. Metode: Studi analitikobservasional dengan rancangan prospektif di Bagian IK. THT-KL RS. Hasan Sadikin Bandung mulaibulan November 2007 sampai dengan Juni 2008. Pada penelitian ini dilakukan pemeriksaan audiometrinada murni, timpanometri, dan distortion product otoacoustic emission (DPOAE) prakemoterapi, kemudianDPOAE dan timpanometri diulang tiga hari sesudah siklus pertama dan kedua kemoterapi sisplatin. Datayang diperoleh diuji dengan uji McNemar dan uji Wilcoxon. Hasil: Dari penelitian didapat 60 telingadari 30 subjek penelitian yang memenuhi kriteria inklusi yang terdiri dari 25 laki-laki (83,3%) dan 5perempuan (16,7%). Insidens penurunan fungsi sel rambut luar koklea sebesar 63% (38 kasus) sesudahsiklus pertama dan 70% (42 kasus) sesudah siklus kedua. Hubungan penurunan fungsi sel rambut luarkoklea memberikan nilai yang sangat bermakna sejak pemberian siklus pertama (p<0,001). Kesimpulan:Pemberian sisplatin dosis tinggi pada penderita tumor ganas menyebabkan penurunan fungsi sel rambutluar koklea.Kata kunci: kemoterapi, sisplatin dosis tinggi, sel rambut luar koklea.


2001 ◽  
Vol 45 (1) ◽  
pp. 43
Author(s):  
Hyo Sung Kwak ◽  
Jeong Min Lee ◽  
Woo Sung Moon ◽  
Shin Hwa Kang ◽  
Jong Deok Lee

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