scholarly journals Granuloma Inguinale

2021 ◽  
Vol 5 (7) ◽  
pp. 632-641
Author(s):  
Adi Agung Anantawijaya D ◽  
Muhammad Izazi Hari Purwoko ◽  
Mutia Devi ◽  
Suroso Adi Nugroho
Keyword(s):  
Clinical Cure ◽  
Treatment Time ◽  
Genital Ulcer ◽  
Men And Women ◽  
Gram Negative ◽  
Ulcer Disease ◽  
Genital Ulcer Disease ◽  
Granuloma Inguinale ◽  
Ulcerative Lesions

Granuloma ingunale (GI) or donovanosis is a genital ulcer disease caused by theCalymmatobacterium granulomatis. It is a Gram-negative, facultative, obligateintracellular and pleomorphic bacterium. This bacterium has phylogeneticallyclosed to and placed within the Klebsiella genus. Clinically, the disease is com-monly characterized as painless, slowly progressive ulcerative lesions on thegenitals or perineum without regional lymphadenopathy. The lesions are highlyvascular and bleed easily on contact Extragenital lesions may occur but are rareand more common in newborns from mothers with GI genital lesions. Thisdisease is often neglected, therefore it is often misdiagnosed and inaccuratetherapy. Treatment time is 3 weeks or until clinical cure has been achieved forall proposed regimens. It often occurs both in men and women of reproductiveage (20-40 years). This article consists of several theoretical references that havebeen viewed to have a better understanding of GI.

scholarly journals Granuloma Inguinale

2021 ◽  
Vol 5 (3) ◽  
pp. 659-668
Author(s):  
Adi Agung Anantawijaya D ◽  
Muhammad Izazi Hari Purwoko ◽  
Mutia Devi ◽  
Suroso Adi Nugroho
Keyword(s):  
Clinical Cure ◽  
Treatment Time ◽  
Genital Ulcer ◽  
Men And Women ◽  
Gram Negative ◽  
Ulcer Disease ◽  
Genital Ulcer Disease ◽  
Granuloma Inguinale ◽  
Ulcerative Lesions

Granuloma ingunale (GI) or donovanosis is a genital ulcer disease caused by theCalymmatobacterium granulomatis. It is a Gram-negative, facultative, obligateintracellular and pleomorphic bacterium. This bacterium has phylogeneticallyclosed to and placed within the Klebsiella genus. Clinically, the disease is com-monly characterized as painless, slowly progressive ulcerative lesions on thegenitals or perineum without regional lymphadenopathy. The lesions are highlyvascular and bleed easily on contact Extragenital lesions may occur but are rareand more common in newborns from mothers with GI genital lesions. Thisdisease is often neglected, therefore it is often misdiagnosed and inaccuratetherapy. Treatment time is 3 weeks or until clinical cure has been achieved forall proposed regimens. It often occurs both in men and women of reproductiveage (20-40 years). This article consists of several theoretical references that havebeen viewed to have a better understanding of GI.

scholarly journals Sexual behaviour in Zulu men and women with genital ulcer disease.

1992 ◽  
Vol 68 (4) ◽  
pp. 245-248
Author(s):  
N O'Farrell ◽  
A A Hoosen ◽  
K D Coetzee ◽  
J van den Ende
Keyword(s):  
Sexual Behaviour ◽  
Genital Ulcer ◽  
Men And Women ◽  
Ulcer Disease ◽  
Genital Ulcer Disease

scholarly journals Acute HIV Infections among Men with Genital Ulcer Disease in South Africa

2010 ◽  
Vol 201 (12) ◽  
pp. 1811-1815 ◽  
Author(s):  
G. Paz Bailey ◽  
M. Sternberg ◽  
D. A. Lewis ◽  
A. Puren
Keyword(s):  
South Africa ◽  
Hiv Infections ◽  
Genital Ulcer ◽  
Ulcer Disease ◽  
Genital Ulcer Disease ◽  
Acute Hiv

The Causal Role for Genital Ulcer Disease as a Risk Factor for Transmission of Human Immunodeficiency Virus

1996 ◽  
Vol 23 (5) ◽  
pp. 429-440 ◽  
Author(s):  
MARY C. DICKERSON ◽  
JEFF JOHNSTON ◽  
THOMAS E. DELEA ◽  
ALICE WHITE ◽  
ELIZABETH ANDREWS
Keyword(s):  
Human Immunodeficiency Virus ◽  
Risk Factor ◽  
Causal Role ◽  
Genital Ulcer ◽  
Ulcer Disease ◽  
Genital Ulcer Disease ◽  
Immunodeficiency Virus

Genital Ulcer Disease

1994 ◽  
Vol 12 (4) ◽  
pp. 753-764 ◽  
Author(s):  
Tomasz F. Mroczkowski ◽  
David H. Martin
Keyword(s):  
Genital Ulcer ◽  
Ulcer Disease ◽  
Genital Ulcer Disease

Etiology of Genital Ulcer Disease in Dakar, Senegal, and Comparison of PCR and Serologic Assays for Detection of Haemophilus ducreyi

2000 ◽  
Vol 38 (1) ◽  
pp. 268-273
Author(s):  
Patricia A. Totten ◽  
Jane M. Kuypers ◽  
Cheng-Yen Chen ◽  
Michelle J. Alfa ◽  
Linda M. Parsons ◽  
...  
Keyword(s):  
Transmitted Disease ◽  
Haemophilus Ducreyi ◽  
Genital Ulcer ◽  
Serological Tests ◽  
Past Infection ◽  
Ulcer Disease ◽  
Sexually Transmitted ◽  
Genital Ulcer Disease ◽  
Pcr Assays ◽  
Simplex Virus

ABSTRACT We used PCR assays to determine the etiology of genital ulcers in patients presenting to a sexually transmitted disease clinic in Dakar, Senegal, and evaluated the ability of two PCR tests ( groEL and recD ) and two serological tests (adsorption enzyme immunoassay [EIA] and lipooligosaccharide [LOS] EIA) to detect current Haemophilus ducreyi infection. We found that in this population, H. ducreyi , T. pallidum , and herpes simplex virus HSV DNA were detected in 56, 15, and 13% of 39 genital ulcer specimens, respectively, and H. ducreyi DNA was detected in 60% (3 of 5) of samples from ulcerated bubos. Among 40 consecutive patients with genital ulcer disease and with sufficient sample for both PCR assays, the recD and groEL H. ducreyi PCR assays were 83% concordant, with the recD PCR assay detecting six (15%) additional positive specimens and the groEL assay detecting one (3%) additional positive specimen. Compared to PCR, the adsorption EIA and LOS EIA tests had sensitivities of 71 and 59% and specificities of 57 and 90%, respectively, for the diagnosis of current H. ducreyi infection. While these differences in specificity could be due either to previous infection with H. ducreyi or to the detection of cross-reacting antibodies, only 6% of patients from a nearby family planning clinic gave a positive reaction in both the adsorption EIA and LOS EIA assays, indicating that cross-reacting antibodies are not prevalent among clinic attendees in this city. Our studies indicate that the adsorption EIA detects both current and past infection, while the LOS EIA assay is more specific for current infection with H. ducreyi in this population.

Genital Ulcer Disease

2008 ◽  
pp. 577-586
Author(s):  
Elizabeth L. Brown ◽  
Carey Farquhar
Keyword(s):  
Genital Ulcer ◽  
Ulcer Disease ◽  
Genital Ulcer Disease

scholarly journals The Etiology of Genital Ulcer Disease and Coinfections With Chlamydia trachomatis and Neisseria gonorrhoeae in Zimbabwe

2018 ◽  
Vol 45 (1) ◽  
pp. 61-68 ◽  
Author(s):  
More Mungati ◽  
Anna Machiha ◽  
Owen Mugurungi ◽  
Mufuta Tshimanga ◽  
Peter H. Kilmarx ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Neisseria Gonorrhoeae ◽  
Genital Ulcer ◽  
Ulcer Disease ◽  
Genital Ulcer Disease
Sign in / Sign up

Export Citation Format

Share Document