scholarly journals A STUDY FOR COMPARISON OF CAREGIVER BURDEN AND BEHAVIORAL AND PSYCHOTIC SYMPTOMS IN FRONTOTEMPORAL DEMENTIA AND ALZHEIMER’S DEMENTIA

2020 ◽  
Vol 4 (2) ◽  
Author(s):  
Nirad Yadav ◽  
Sanjay Jain ◽  
Richa Jain
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Caregiver Burden ◽  
Significant Positive Correlation ◽  
Psychological Symptoms ◽  
Behavioral Problem ◽  
Psychotic Symptoms ◽  
Psychiatric Clinic ◽  
Positive Correlation ◽  
Dementia Patients

Background:  Dementia is a syndrome that results in the progressive deterioration of cortical functioning including comprehension, memory and thinking. Alzheimer’s disease (AD) is the most common cause of dementia accounting for 50-75% and Front temporal dementia (FTD) around 5-10% of dementia cases. Behavioral and psychological symptoms (BPSD) form a major part of the presentation of the dementia patients at psychiatric clinic and play a crucial role in caregiver distress which in turn is a major determinant of welfare of dementia patients in society. Objective:  Present study is to compare care giver burden and BPSD in patients with FTD and AD. Method:  We compared 41 patients’, of which 15 of FTD and 26 of AD with respect to the Neuropsychiatric Inventory (NPI), Hindi Mental State Examination (HMSE) and Zarit Burden Inventory (ZBI) at SMS Medical College, Jaipur. Results: FTD patients obtained a significantly higher NPI behavioral score And ZBI than AD patients and mean value of HMSE is higher in FTD than AD. Significant positive correlation between NPI and ZBI is observed in both groups. Significant positive correlation between HMSE and ZBI is found in FTD obtained, Conclusion: More behavioral problem in FTD makes it difficult for patient’s caregiver to manage patients at home this leads to rapid institutionalization, although severity of dementia is less. Keywords: Alzheimer’s disease, Front temporal dementia, BPSD, Caregiver Burden

scholarly journals Caregiver burden of behavioral and psychological symptoms of dementia among Indian patients with Alzheimer's disease

2012 ◽  
Vol 24 (9) ◽  
pp. 1531-1532 ◽  
Author(s):  
Vikas Dhikav ◽  
Kuljeet Singh Anand
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Caregiver Burden ◽  
Disease Burden ◽  
Psychological Symptoms ◽  
Indian Patients ◽  
Behavioral And Psychological Symptoms

Behavioral and psychological symptoms of dementia (BPSD) are common in Alzheimer's disease (AD) and can potentially contribute to disease burden among caregivers. In this letter, an attempt is reported to establish if disease burden was higher among those with BPSD compared to those without it.

Behavioral and Psychological Signs and Symptoms of Dementia (BPSD) in antipsychotic-naïve Alzheimer's Disease patients

2004 ◽  
Vol 16 (3) ◽  
pp. 337-350 ◽  
Author(s):  
Guk-Hee Suh ◽  
Seung Kyum Kim
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Psychological Symptoms ◽  
Severity Of Illness ◽  
Signs And Symptoms ◽  
Community Dwelling ◽  
Global Deterioration Scale ◽  
Dementia Patients ◽  
Elderly Koreans ◽  
At Home

Background/Objective: There were few studies identifying the natural unfolding of behavioural and psychological symptoms of dementia (BPSD) in the course of Alzheimer's disease (AD) progression in antipsychotic-naïve AD patients. This study aims to examine the specific nature of the association between BPSD in AD and the global severity of illness measured by Global Deterioration Scale(GDS) in antipsychotic-naïve AD patients in Korea.Methods: A total of 562 antipsychotics-naïve AD patients were recruited from four different groups [a geriatric mental hospital (n=145), a semi-hospitalized dementia institution (n=120), a dementia clinic (n=114) and community-dwelling dementia patients (n=183)]. BPSD exhibited by AD patients were measured using the 25-item Korean version of the BEHAVE-AD.Results: Ninety-two percent (n=517) of AD patients had at least one BPSD, while 56% (n=315) had 4 or more BPSD. Specific kinds of behavioral disturbance peak at the stages of moderate AD (GDS stage 5) or moderately severe AD (GDS stage 6). AD patients left at home without any treatment had higher frequency of BPSD than did other groups seeking treatment, although all of them were antipsychotic-naïve.Conclusion: BPSD potentially remediable to treatment were highly frequent in Korean AD patients. Health policies to meet the unmet needs of elderly Koreans are urgently needed, especially for AD patients at home without treatment.

scholarly journals Alzheimer's Alphabet Soup: ADRD research in NHATS and NSOC

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 435-435
Author(s):  
Loretta Anderson ◽  
Alexandra Wennberg ◽  
Frank Lin
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Caregiver Burden ◽  
Functional Decline ◽  
Cognitive Outcomes ◽  
National Study ◽  
Dementia Patients ◽  
Nationally Representative ◽  
And Function

Abstract There are 5.8 million Americans living with Alzheimer’s disease, but currently there is no cure or effective treatment. Alzheimer’s disease and related dementias (ADRD) are characterized by cognitive decline, but patients also have behavioral symptoms and functional decline. Understanding the gamut of risk and prognostic factors for ADRD and those associated with the task of caring for these patients is layered. The National Health and Aging Trends Study (NHATS) and the sister National Study of Caregiving (NSOC) are excellent resources to investigate layers of ADRD incidence, progression, and caregiving in the population. NHATS is a nationally representative sample of Medicare beneficiaries aged 65 and older. Since 2011, annual in-person interviews have collected data in many areas, including health, environment, wellbeing, cognition, and function. NSOC has been conducted at three timepoints corresponding with NHATS rounds and collects detailed data on caregivers, including information on care activities, caregiver burden, and caregiver wellbeing. This symposium illustrates the broad range of ADRD research questions that can be probed using NHATS/NSOC data. The session begins with a presentation the association between caregiver burden and ADRD patient cognitive outcomes. The second presentation examines the role of physical performance as a predictor of developing ADRD. The third presentation investigates the role of dual sensory impairment – both hearing and vision impairment – on dementia incidence. The session concludes with an examination of whether hearing impairment among dementia patients is associated with different caregiving needs.

scholarly journals Evidence against a geographic gradient of Alzheimer's disease and the hygiene hypothesis

2020 ◽  
Vol 2020 (1) ◽  
pp. 141-144
Author(s):  
J Constance Lathe ◽  
Richard Lathe
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Risk Factor ◽  
Significant Positive Correlation ◽  
Parasite Burden ◽  
Hygiene Hypothesis ◽  
World Health ◽  
Positive Correlation ◽  
Geographic Gradient ◽  
Health Organization

Abstract A significant positive correlation was previously reported (Fox et al.Evol Med Public Health 2013; 2013:173–86) between hygiene and the global prevalence of Alzheimer's disease (AD) based on World Health Organization (2004) data. These data have now been updated by the Global Burden of Disease (GBD; 2016) dataset that takes into account under-registration and other potential confounds. We therefore addressed whether the association between hygiene and AD is maintained in light of these more recent data. We report a significant positive correlation between GBD AD prevalence rates and parasite burden, and a negative association with hygiene. These newer data argue that hygiene is not a risk factor for AD, and instead suggest that parasite burden may increase AD risk. Lay summary: It was previously hypothesized that hygeine might be a risk factor for the development of Alzheimer disease (AD), based on a global gradient of dementia. Newer data that correct global AD rates for under-reporting now demonstrate that parasite burden is positively correlated with AD.

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