scholarly journals MUCINOUS ADENOCARCINOMA OF GALL BLADDER: A RARE ENTITY IN GALL BALDDER ADENOCARCINOMA

2020 ◽  
Vol 4 (3) ◽  
Author(s):  
Sushil Kumar Shukla ◽  
Rohini Garg ◽  
Dushyant Gaur ◽  
Anshika Arora ◽  
Anuradha Kusum
Keyword(s):  
Gall Bladder ◽  
Mucinous Adenocarcinoma ◽  
Mucinous Carcinoma ◽  
Rare Entity ◽  
Gall Bladder Carcinoma ◽  
Mucinous Component ◽  
Carcinoma Gall Bladder ◽  
Signet Ring ◽  
Bladder Adenocarcinoma ◽  
Histopathological Subtype

Gall bladder carcinoma is the most common type of tumor of the biliary tract and adenocarcinoma is the major histopathological subtype. Mucinous variant is a rare subtype and mucinous carcinoma accompanied with signet ring is extremely rare. When mucinous component exceeds 90% of the tumor, it is labeled as pure mucinous carcinoma. Immunohistochemistry helps to distinguish primary mucinous adenocarcinoma of gall bladder from pseudo myxoma peritonei from appendiceal neoplasm. Mucinous carcinoma is CK 7 positive and CK20 negative. We report a case of mucinous adenocarcinoma arising from the fundus of the gall bladder. Keywords: Mucinous carcinoma, Gall bladder, Adenocarcinoma, Metastatic deposits

scholarly journals Mucinous adenocarcinoma of gall bladder: a case report

2017 ◽  
Vol 5 (11) ◽  
pp. 5082 ◽  
Author(s):  
Ashwini Radhakishan Tangde ◽  
Santosh Govind Rathod ◽  
Anil R. Joshi ◽  
Rajan S. Bindu
Keyword(s):  
Gall Bladder ◽  
Bladder Carcinoma ◽  
Mucinous Adenocarcinoma ◽  
Bladder Neck ◽  
Mucinous Carcinoma ◽  
Muscle Layer ◽  
Solid Mass ◽  
Gall Bladder Carcinoma ◽  
Hypochondriac Region ◽  
Common Malignancy

Gall bladder carcinoma is the fifth most common malignancy of gastrointestinal tract. Mucinous carcinoma of gall bladder is very rare variant of gall bladder carcinoma. Only 20 cases of mucinous carcinoma reported till now. We report one such case of 55yr old female patient presented to our hospital with complaining of pain in right hypochondriac region and vomiting since, one month. Radiological examination revealed neoplastic thickening of gall bladder neck with cholelithiasis. Cholecystectomy was performed and specimen showed glistening grey white infiltrative firm solid mass at the neck of gall bladder. On microscopic examination showed mucinous adenocarcinoma. Tumour comprised of cystically dilated mucin filled glands. Tumour was seen infiltrating into muscle layer.

scholarly journals Mucinous Carcinoma of Gall Bladder – A Rare Case Report

2021 ◽  
Vol 11 (6) ◽  
pp. 326-328
Author(s):  
Nanda Patil ◽  
Vaidehi Nagar
Keyword(s):  
Case Report ◽  
Gall Bladder ◽  
Histopathological Examination ◽  
Mucinous Carcinoma ◽  
Tumour Volume ◽  
Definitive Diagnosis ◽  
Gall Bladder Carcinoma ◽  
Rare Type ◽  
Carcinoma Gall Bladder ◽  
Rare Case Report

Background: Mucinous carcinoma of the gall bladder is a very rare type of gall bladder carcinoma. It is characterized by production of extracellular mucin >50% of tumour volume. Case Report: We report a case of primary mucinous carcinoma of gall bladder in a 60-year-old female patient who was diagnosed clinically as acute cholecystitis. Histopathological examination gave the definitive diagnosis in this case. Conclusion: Mucinous carcinoma of gall bladder exhibit significant clinicopathological difference from conventional adenocarcinoma of gall bladder and display aggressive clinical behaviour. Key words: Mucinous Carcinoma, Gall Bladder, Primary.

Frequency of gall bladder carcinoma in cholecystectomies for symptomatic cholelithiasis

2020 ◽  
pp. 1-4
Author(s):  
Muhammad Amar Qudeer ◽  
Syed Asghar Naqi ◽  
Muhammad Zeeshan Sarwar ◽  
Hafiza Amina Mujahid ◽  
Admin
Keyword(s):  
Survival Rate ◽  
Gall Bladder ◽  
Gall Bladder Carcinoma ◽  
Stone Size ◽  
Gastrointestinal Malignancies ◽  
Gallbladder Polyps ◽  
Symptomatic Cholelithiasis ◽  
Carcinoma Gall Bladder ◽  
Gall Stones ◽  
Carcinoma Gallbladder

It was a Letter to the Editor to find out the frequency of carcinoma gall bladder in patients which were presented with symptomatic cholelithiasis. Carcinoma of the gallbladder is a rear malignancy with 5 year survival rate of 5%. Carcinoma gall bladder is the most common billiary tract malignancy, it is also 5th most common in gastrointestinal malignancies 1. In Pakistan the incidence of carcinoma gallbladder among patients having symptomatic cholelithiasis is 6 to 28%2. Patients with symptomatic gall stones had more risk for developing carcinoma gallbladder as compared to asymptomatic gall stones. Large stones in cholelithiasis are more dangerous than small stones as stone size reaches >3cm risk increases upto 10 fold. Gallbladder polyps >10mm, calcified(porcelain) gallbladder, choledochal cyst, seclerosing cholangitis, anomalous pancreaticobillary junctions and exposure to carcinogens are other risk factors3. Continuous...

scholarly journals Pure mucinous (colloid) carcinoma of gall bladder: a rare entity

2017 ◽  
Vol 4 (8) ◽  
pp. 2858
Author(s):  
Gireesha Rawal ◽  
Charanjeet Ahluwalia ◽  
Amit Kumar Yadav ◽  
Indrani Dhawan
Keyword(s):  
Case Report ◽  
Natural History ◽  
Gall Bladder ◽  
Histopathological Examination ◽  
Mucinous Carcinoma ◽  
Final Diagnosis ◽  
Tumour Volume ◽  
Rare Entity ◽  
Hypochondriac Region ◽  
Cut Surface

In the biliary tract, ‘mucinous’ carcinomas in which extracellular mucin constitutes more than 50% of the tumour volume, are very rare. Those tumours in which the mucinous pattern comprises of at least 90% of the tumour are called ‘pure mucinous’ carcinomas and are exceedingly rare in the gallbladder. We describe the case of a 55 years old female, who presented with the complaints of jaundice and dull aching pain in right hypochondriac region. USG abdomen was suggestive of carcinoma along with cholelithiasis, following which cholecystectomy was performed. Grossly, a large grey-white tumour was identified whose cut surface was variegated. Sections showed a tumour which was entirely composed of pools of extracellular mucin, in which clusters of tumour cells were floating. Based on morphology and immunohistochemistry, a final diagnosis of ‘pure mucinous (colloid) adenocarcinoma’ of the gallbladder was given. This case is described owing to the rarity of this neoplasm. The clinical features, natural history and prognosis of mucinous carcinoma of GB are not very well known, due to their extreme rarity. These have been discussed in this case report. Histopathological examination is vital for a decisive diagnosis of such cases. 

Clinicopathological study of gall bladder carcinoma: Our experience from Patan Hospital, Patan Academy of Health Sciences

2019 ◽  
Vol 22 (2) ◽  
pp. 4-10
Author(s):  
Sanjaya Paudyal ◽  
Shiva Raj K.C. ◽  
Shanta Bir Maharjan ◽  
Surendra Shah ◽  
Niraj Giri
Keyword(s):  
Gall Bladder ◽  
Bladder Carcinoma ◽  
Advanced Disease ◽  
Radical Surgery ◽  
Curative Treatment ◽  
Common Disease ◽  
Radical Excision ◽  
Gall Bladder Carcinoma ◽  
Surgical Department ◽  
Carcinoma Gall Bladder

Introduction: Gall bladder carcinoma is not a common disease. The overall prevalence is low worldwide. It is a highly malignant tumor with a poor prognosis. The outcome of gallbladder carcinoma is poor, and the overall 5-year survival rate is less than 5%. The carcinoma gall bladder is 2-6 times more common in females compared to males and its incidence increases with increasing age. Aggressive surgical management and preoperative adjuvant therapy have helped to prolong survival in patients with gallbladder cancer. We conducted a study with an aim to evaluate the clinicopathological aspect of the disease in patients of gall bladder cancer managed in our surgical department. Methods: Data were recorded retrospectively by reviewing the charts of the patients who were diagnosed and treated for carcinoma gall bladder in Patan hospital from Aug 2017 to Aug 2019. Results: Thirty patients were included in the study. Twenty (66.7%) were female and ten (33.33%) were males. Age ranged from 36 to 83 years with the median age of presentation at 63.5 yrs. Curative treatment was possible in 43.33% of the patients, among them 12 had radical surgery and one had cholecystectomy alone for the T1a stage.  All other (56.6%) required palliative treatment. One patient developed liver metastasis within six months of radical excision. Conclusions: The majority of the patients present with an advanced disease which makes it less chance for curative surgical resection. Since only palliative care is possible in an advanced stage, early detection and curative treatment are advisable.

Cystic dilatation of cystic duct with associated carcinoma gall bladder: A rare entity

2010 ◽  
Vol 75 (2) ◽  
pp. e63-e67
Author(s):  
Maneesh Khanna ◽  
Shanker Rao Buddhavarapu ◽  
Habeeba Hena ◽  
Emran Amir
Keyword(s):  
Gall Bladder ◽  
Cystic Duct ◽  
Rare Entity ◽  
Cystic Dilatation ◽  
Carcinoma Gall Bladder

scholarly journals INCIDENCE OF GALL BLADDER CARCINOMA: A RETROSPECTIVE CASE STUDY AT RIMS RANCHI

2021 ◽  
pp. 12-13
Author(s):  
Nasrin Parwin ◽  
Jayashree Maity ◽  
Sona Pathak
Keyword(s):  
Gall Bladder ◽  
Bladder Carcinoma ◽  
Common Finding ◽  
Retrospective Case ◽  
Gall Bladder Carcinoma ◽  
Clinical Presentations ◽  
Bladder Diseases ◽  
Study Population ◽  
Retrospective Case Study ◽  
Bladder Adenocarcinoma

BACKGROUND: Gall bladder carcinoma is most common malignancy of the biliary tract and seventh most common gastrointestinal malignancy. Histologically most gall bladder carcinoma are pancreaticobiliary type adenocarcinoma, showing variable degrees of differentiation.The determination of the histology type of tumour and differential diagnosis from gall bladder adenocarcinoma are often difficult. It has unique significant and striking gender, geographic and ethnic variation in the incidence worldwide. MATERIAL AND METHOD: It is retrospective record based study, performed in department of Pathology RIMS, Ranchi. Study population included all cases who were operated for different pathology of gall bladder,with some common clinical presentations of upper right quadrant abdominal pain, jaundice, nausea and vomiting, from January 2018-December 2019. RESULT: Among the spectrum of gall bladder diseases most common finding was chronic cholecystitis, incidence of gall bladder carcinoma is a rare entity. In our present study female preponderance has been noted and mostly incidence is among the age group above 30 years.

Sign in / Sign up

Export Citation Format

Share Document