Stevens-Johnson Syndrome, fisiopatológics aspects: A literature review

Author(s):  
Alex Ferreira de Oliveira ◽  
Ingrith do Socorro Neves da Silva ◽  
Lídia Pinheiro de Brito ◽  
Rebeca Luiza Abreu Pereira ◽  
Amanda Alves Fecury ◽  
...  
2020 ◽  
Vol 17 (3) ◽  
pp. 169-173
Author(s):  
Takahiro Goto ◽  
Atsushi Yamashiro ◽  
Nobuyuki Maruyama ◽  
Fusahiro Hirano ◽  
Toshiyuki Nakasone ◽  
...  

Cureus ◽  
2019 ◽  
Author(s):  
Mustafa N Malik ◽  
Ateeqa Mujeeb Ullah ◽  
Muhaddis Ejaz Ahmad ◽  
Rida Riaz ◽  
Tariq Iqtidar Sadiq Syed

2019 ◽  
Vol 22 (4) ◽  
pp. 661 ◽  
Author(s):  
Victoria López-Gómez ◽  
Ramón Yarza ◽  
Héctor Muñoz-González ◽  
Enrique Revilla ◽  
Santos Enrech ◽  
...  

2011 ◽  
Vol 10 (2) ◽  
pp. 81-82
Author(s):  
DCR McGouran ◽  
◽  
T Petterson ◽  
JM McLaren ◽  
MP Wolbinski ◽  
...  

The Stevens-Johnson syndrome (SJS) classically involves a rash, conjunctivitis and mucositis. We describe the case of a young adult male with isolated mucositis and conjunctivitis . Previous rare reports of severe SJS like syndromes without a rash are confined to children, usually with mycoplasma pnemoniae infection.1 Terminology for this syndrome includes – “Stevens-Johnson Syndrome without skin lesions”, or “Atypical Stevens – Johnson Syndrome”.2 This case highlights the importance of maintaining an open mind when a “full house” of clinical features is absent. It also illustrates the use of a rapid electronic literature review as a clinical tool. The importance of updating records when a drug has been cleared of causing harm is highlighted.


2018 ◽  
Vol 26 (6) ◽  
pp. 640-642 ◽  
Author(s):  
Gordon Parker

Objectives: To detail some serious lamotrigine side effects and their management, and raise awareness about the possible lack of quality control of some brands of lamotrigine. Methods: A literature review is provided and some personal observations added. Results: While most psychiatrists are aware of the risks of Stevens–Johnson syndrome (SJS), awareness of two other serious side effects – toxic epidermal necrosis (TEN) and drug-related eosinophilia and systemic symptoms (DRESS) – is seemingly lower. Awareness that failure to respond to lamotrigine and that the prevalence of serious side effects may reflect poor quality control of some preparations is also less well recognized. Conclusions: While lamotrigine may be retrialled at a lower dose escalation rate following some skin reactions, it should not be recommenced following a SJS, TEN or DRESS reaction. Prescribers should be aware of quality control concerns about some available brands of lamotrigine.


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