scholarly journals Sudden death and cardiac arrest in marathon runners: incidence rates and causes

2020 ◽  
Vol 19 (3) ◽  
pp. 243
Author(s):  
Oscar Antonio Santos Targino De Araújo ◽  
Mario Cesar Carvalho Tenório
Keyword(s):  
Coronary Artery Disease ◽  
Cardiac Arrest ◽  
Coronary Artery ◽  
Hypertrophic Cardiomyopathy ◽  
Sudden Death ◽  
Incidence Rates ◽  
Finish Line ◽  
Marathon Runners ◽  
Older Athletes ◽  
Artery Disease

Introduction: The marathon race is an aerobic sport that requires high training volume. Marathon runners may eventually be exposed to unfavorable environmental conditions associated with changes in blood volume and hydration level that may increase the risk of cardiac arrhythmias that can cause cardiac arrest and sudden death. Objective: To identify the existing life risks for marathon runners related to the occurrences of sudden death and cardiac arrest and the most prevalent causes of these events. Methods: Integrative literature review of descriptive-qualitative nature in the databases: Google, Academic Google, Medline, Scielo and Pubmed. Results: Sudden death incidence rates ranged from 0.75 to 2.0 per 100.000 runners while cardiac arrest rates ranged from 1.01 to 2.6 per 100.000 runners being men most susceptible to these events. Among the causes of sudden death and cardiac arrest, studies indicate that in older athletes (age > 45 years) coronary artery disease (CAD) is the most prevalent and in younger athletes (age < 45 years) structural and congenital causes are the most common as hypertrophic cardiomyopathy. Most of the events of sudden death and cardiac arrest occurred in the last quartile of the race or after the finish line. Conclusion: The risks of sudden death and cardiac arrest in marathons are low and higher in men being coronary artery disease and hypertrophic cardiomyopathy the most prevalent causes of these events.Keywords: sudden, death, sudden cardiac death, hypertrophic cardiomyopathy, exercise, heart arrest.

Risk Stratification for Coronary Artery Disease in Marathon Runners

2008 ◽  
Vol 4 (1) ◽  
pp. 23
Author(s):  
Stefan Möhlenkamp ◽  
Raimund Erbel ◽  
Gerd Heusch ◽  
◽  
◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Risk Stratification ◽  
Marathon Runners ◽  
Artery Disease

scholarly journals Infarct-related chronic total coronary occlusion and the risk of ventricular tachyarrhythmic events in out-of-hospital cardiac arrest survivors

2021 ◽  
Author(s):  
M. van der Graaf ◽  
L. S. D. Jewbali ◽  
J. S. Lemkes ◽  
E. M. Spoormans ◽  
M. van der Ent ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Cardiac Arrest ◽  
Coronary Artery ◽  
Coronary Occlusion ◽  
Independent Factor ◽  
St Segment Elevation ◽  
St Segment ◽  
Artery Disease ◽  
Chronic Total Coronary Occlusion ◽  
Hospital Cardiac Arrest

Abstract Introduction Chronic total coronary occlusion (CTO) has been identified as a risk factor for ventricular arrhythmias, especially a CTO in an infarct-related artery (IRA). This study aimed to evaluate the effect of an IRA-CTO on the occurrence of ventricular tachyarrhythmic events (VTEs) in out-of-hospital cardiac arrest survivors without ST-segment elevation. Methods We conducted a post hoc analysis of the COACT trial, a multicentre randomised controlled trial. Patients were included when they survived index hospitalisation after cardiac arrest and demonstrated coronary artery disease on coronary angiography. The primary endpoint was the occurrence of a VTE, defined as appropriate implantable cardioverter-defibrillator (ICD) therapy, sustained ventricular tachyarrhythmia or sudden cardiac death. Results A total of 163 patients from ten centres were included. Unrevascularised IRA-CTO in a main vessel was present in 43 patients (26%). Overall, 61% of the study population received an ICD for secondary prevention. During a follow-up of 1 year, 12 patients (7.4%) experienced at least one VTE. The cumulative incidence rate of VTEs was higher in patients with an IRA-CTO compared to patients without an IRA-CTO (17.4% vs 5.6%, log-rank p = 0.03). However, multivariable analysis only identified left ventricular ejection fraction < 35% as an independent factor associated with VTEs (adjusted hazard ratio 8.7, 95% confidence interval 2.2–35.4). A subanalysis focusing on CTO, with or without an infarct in the CTO territory, did not change the results. Conclusion In out-of-hospital cardiac arrest survivors with coronary artery disease without ST-segment elevation, an IRA-CTO was not an independent factor associated with VTEs in the 1st year after the index event.

scholarly journals Myocardial Fibrosis as a Predictor of Sudden Death in Patients With Coronary Artery Disease

2021 ◽  
Vol 77 (1) ◽  
pp. 29-41
Author(s):  
Abbasin Zegard ◽  
Osita Okafor ◽  
Joseph de Bono ◽  
Manish Kalla ◽  
Mauro Lencioni ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Sudden Death ◽  
Myocardial Fibrosis ◽  
Artery Disease

scholarly journals Effect of empiric antiarrhythmic therapy in resuscitated out-of-hospital cardiac arrest victims with coronary artery disease

1990 ◽  
Vol 65 (18) ◽  
pp. 1192-1197 ◽  
Author(s):  
Ali R. Moosvi ◽  
Sidney Goldstein ◽  
Sharon VanderBrug Medendorp ◽  
J.Richard Landis ◽  
Robert A. Wolfe ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Cardiac Arrest ◽  
Coronary Artery ◽  
Antiarrhythmic Therapy ◽  
Artery Disease ◽  
Hospital Cardiac Arrest

scholarly journals Coronary Artery Disease in Patients With Out-of-Hospital Refractory Ventricular Fibrillation Cardiac Arrest

2017 ◽  
Vol 70 (9) ◽  
pp. 1109-1117 ◽  
Author(s):  
Demetris Yannopoulos ◽  
Jason A. Bartos ◽  
Ganesh Raveendran ◽  
Marc Conterato ◽  
Ralph J. Frascone ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Cardiac Arrest ◽  
Coronary Artery ◽  
Ventricular Fibrillation ◽  
Artery Disease

Abstract P380: Coronary Artery Disease Extent is Predictive of Heart Failure Incidence After Myocardial Infarction

Circulation ◽  
2015 ◽  
Vol 131 (suppl_1) ◽  
Author(s):  
Yariv Gerber ◽  
Susan A Weston ◽  
Maurice E Sarano ◽  
Sheila M Manemann ◽  
Alanna M Chamberlain ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Heart Failure ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Proportional Hazards ◽  
Incidence Rates ◽  
Cox Proportional Hazards ◽  
Disease Extent ◽  
Increased Risk ◽  
Artery Disease

Background: Little is known about the association between coronary artery disease (CAD) and the risk of heart failure (HF) after myocardial infarction (MI), and whether it differs by reduced (HFrEF) or preserved (HFpEF) ejection fraction (EF) has yet to be determined. Subjects and Methods: Olmsted County, Minnesota residents (n=1,924; mean age, 64 years; 66% male) with first MI diagnosed in 1990-2010 and no prior HF were followed through 2013. Framingham Heart Study criteria were used to define HF, which was further classified according to EF (applying a 50% cutoff). The extent of angiographic CAD was defined at index MI according to the number of major epicardial coronary arteries with ≥50% lumen diameter obstruction. Fine & Gray and Cox proportional hazards regression models were used to assess the association of CAD categories with incidence of HF, and multiple imputation methodology was applied to account for the 19% with missing EF data. Results: During a mean (SD) follow-up of 6.7 (5.9) years, 594 patients developed HF. Adjusted for age and sex, with death considered a competing risk, the cumulative incidence rates of HF among patients with 1- (n=581), 2- (n=622), and 3-vessel disease (n=721) were 11.2%, 14.6% and 20.5% at 30 days; and 18.1%, 22.3% and 29.4% at 5 years after MI, respectively. The increased risk of HF with greater number of occluded vessels was only modestly attenuated after further adjustment for patient and MI characteristics, and did not differ materially by EF (Table). Conclusions: The extent of angiographic CAD expressed by the number of diseased vessels is independently associated with HF incidence after MI. The association is evident promptly after MI and applies to both HFrEF and HFpEF.

Familial clustering of cardiac conditions in patients with anomalous aortic origin of a coronary artery and myocardial bridges

2018 ◽  
Vol 28 (9) ◽  
pp. 1099-1105 ◽  
Author(s):  
Hitesh Agrawal ◽  
Carlos M. Mery ◽  
S. Kristen Sexson Tejtel ◽  
Charles D. Fraser ◽  
E. Dean McKenzie ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Cardiac Arrest ◽  
Coronary Artery ◽  
Family History ◽  
Positive Family History ◽  
Sudden Cardiac Arrest ◽  
Coronary Anomalies ◽  
Myocardial Bridge ◽  
Familial Clustering ◽  
Artery Disease

AbstractBackgroundAnomalous aortic origin of a coronary artery is the second leading cause of sudden cardiac arrest/death in young athletes in the United States of America. Limited data are available regarding family history in this patient population.MethodsPatients were evaluated prospectively from 12/2012 to 02/2017 in the Coronary Anomalies Program at Texas Children’s Hospital. Relevant family history included the presence of CHD, sudden cardiac arrest/death, arrhythmia/pacemaker use, cardiomyopathy, and atherosclerotic coronary artery disease before the age of 50 years. The presence of one or more of these in 1st- or 2nd-degree relatives was considered significant.ResultsOf 168 unrelated probands (171 patients total) included, 36 (21%) had significant family history involving 19 (53%) 1st-degree and 17 (47%) 2nd-degree relatives. Positive family history led to cardiology referral in nine (5%) patients and the presence of abnormal tests/symptoms in the remaining patients. Coronary anomalies in probands with positive family history were anomalous right (27), anomalous left (five), single right coronary artery (two), myocardial bridge (one), and anomalous circumflex coronary artery (one). Conditions present in their family members included sudden cardiac arrest/death (15, 42%), atherosclerotic coronary artery disease (14, 39%), cardiomyopathy (12, 33%), CHD (11, 31%), coronary anomalies (3, 8%), myocardial bridge (1, 3%), long-QT syndrome (2, 6%), and Wolff–Parkinson–White (1, 3%).ConclusionIn patients with anomalous aortic origin of a coronary artery and/or myocardial bridges, there appears to be familial clustering of cardiac diseases in approximately 20% of patients, half of these with early occurrence of sudden cardiac arrest/death in the family.

Sign in / Sign up

Export Citation Format

Share Document