Randomized multicenter phase II study of flavopiridol (alvocidib), cytarabine, and mitoxantrone (FLAM) versus cytarabine/daunorubicin (7+3) in newly diagnosed acute myeloid leukemia

J. F. Zeidner; M. C. Foster; A. L. Blackford; M. R. Litzow; L. E. Morris; S. A. Strickland; J. E. Lancet; P. Bose; M. Y. Levy; R. Tibes; I. Gojo; C. D. Gocke; G. L. Rosner; R. F. Little; J. J. Wright; L. A. Doyle; B. D. Smith; J. E. Karp

doi:10.3324/haematol.2015.125849

Randomized multicenter phase II study of flavopiridol (alvocidib), cytarabine, and mitoxantrone (FLAM) versus cytarabine/daunorubicin (7+3) in newly diagnosed acute myeloid leukemia

Haematologica ◽

10.3324/haematol.2015.125849 ◽

2015 ◽

Vol 100 (9) ◽

pp. 1172-1179 ◽

Cited By ~ 56

Author(s):

J. F. Zeidner ◽

M. C. Foster ◽

A. L. Blackford ◽

M. R. Litzow ◽

L. E. Morris ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Phase Ii ◽

Myeloid Leukemia ◽

Phase Ii Study ◽

Newly Diagnosed ◽

Multicenter Phase ◽

Acute Myeloid

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Final results of a randomized multicenter phase II study of alvocidib, cytarabine, and mitoxantrone versus cytarabine and daunorubicin (7 + 3) in newly diagnosed high-risk acute myeloid leukemia (AML)

Leukemia Research ◽

10.1016/j.leukres.2018.08.005 ◽

2018 ◽

Vol 72 ◽

pp. 92-95 ◽

Cited By ~ 12

Author(s):

Joshua F. Zeidner ◽

Matthew C. Foster ◽

Amanda L. Blackford ◽

Mark R. Litzow ◽

Lawrence E. Morris ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

High Risk ◽

Phase Ii ◽

Myeloid Leukemia ◽

Phase Ii Study ◽

Newly Diagnosed ◽

Multicenter Phase ◽

Acute Myeloid

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A phase II study of decitabine and gemtuzumab ozogamicin in newly diagnosed and relapsed acute myeloid leukemia and high-risk myelodysplastic syndrome

Leukemia ◽

10.1038/leu.2015.244 ◽

2015 ◽

Vol 30 (2) ◽

pp. 268-273 ◽

Cited By ~ 40

Author(s):

N Daver ◽

H Kantarjian ◽

F Ravandi ◽

E Estey ◽

X Wang ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

High Risk ◽

Myelodysplastic Syndrome ◽

Phase Ii ◽

Myeloid Leukemia ◽

Phase Ii Study ◽

Gemtuzumab Ozogamicin ◽

Newly Diagnosed ◽

Relapsed Acute Myeloid Leukemia ◽

Acute Myeloid

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Randomized multicenter phase II trial of timed-sequential therapy with flavopiridol (alvocidib), cytarabine, and mitoxantrone (FLAM) versus “7+3” for adults with newly diagnosed acute myeloid leukemia (AML).

Journal of Clinical Oncology ◽

10.1200/jco.2014.32.15_suppl.7002 ◽

2014 ◽

Vol 32 (15_suppl) ◽

pp. 7002-7002

Author(s):

Joshua F. Zeidner ◽

Matthew C. Foster ◽

Amanda Blackford ◽

Mark Robert Litzow ◽

Lawrence Morris ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Phase Ii ◽

Myeloid Leukemia ◽

Phase Ii Trial ◽

Sequential Therapy ◽

Newly Diagnosed ◽

Multicenter Phase ◽

Acute Myeloid

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A prospective, multicenter phase II study of continuous infusion of FLAG for patients older than 60 yr with resistant acute myeloid leukemia: a comparison with intensive younger patients’ trial

European Journal Of Haematology ◽

10.1111/ejh.12568 ◽

2015 ◽

Vol 96 (2) ◽

pp. 188-197 ◽

Cited By ~ 11

Author(s):

Hawk Kim ◽

Je-Hwan Lee ◽

Young-Don Joo ◽

Sung Hwa Bae ◽

Jung-Hee Lee ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Continuous Infusion ◽

Phase Ii ◽

Myeloid Leukemia ◽

Phase Ii Study ◽

Younger Patients ◽

Multicenter Phase ◽

Acute Myeloid

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Combination of mitoxantrone and etoposide in the Treatment of Advanced MyelodysplasticSyndrome/Secondary Acute Myeloid Leukemia - a Multicenter Phase II Study

TumorDiagnostik & Therapie ◽

10.1055/s-2002-26771 ◽

2002 ◽

Vol 23 (2) ◽

pp. 57-61

Author(s):

C. Baldus ◽

L. Balleisen ◽

W. Hirschmann ◽

C. Rudolph ◽

H. Bartels ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Phase Ii ◽

Myeloid Leukemia ◽

Phase Ii Study ◽

Secondary Acute Myeloid Leukemia ◽

Multicenter Phase ◽

Acute Myeloid

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Imatinib mesylate in the treatment of newly diagnosed or refractory/resistant c-KIT positive acute myeloid leukemia. Results of an italian multicentric phase II study.

Haematologica ◽

10.3324/haematol.11345 ◽

2007 ◽

Vol 92 (12) ◽

pp. 1721-1722 ◽

Cited By ~ 13

Author(s):

P. P. Piccaluga ◽

M. Malagola ◽

M. Rondoni ◽

M. Arpinati ◽

S. Paolini ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Imatinib Mesylate ◽

Phase Ii ◽

Myeloid Leukemia ◽

Phase Ii Study ◽

Newly Diagnosed ◽

Acute Myeloid

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Continuous infusion of intermediate-dose cytarabine and fludarabine with idarubicin for patients younger than 60 years with resistant acute myeloid leukemia: A prospective, multicenter phase II study

American Journal of Hematology ◽

10.1002/ajh.21351 ◽

2009 ◽

Vol 84 (3) ◽

pp. 161-166 ◽

Cited By ~ 5

Author(s):

Hawk Kim ◽

Jae-Hoo Park ◽

Je-Hwan Lee ◽

Jung-Hee Lee ◽

Young-Don Joo ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Continuous Infusion ◽

Phase Ii ◽

Myeloid Leukemia ◽

Phase Ii Study ◽

Multicenter Phase ◽

Acute Myeloid ◽

Intermediate Dose

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Prospective, Multicenter, Phase II Study on Reducing the Dosage of Idarubicin and FLAG for Patients Younger than 65 Years with Resistant Acute Myeloid Leukemia: A Comparison with a Higher Dosage Trial

Acta Haematologica ◽

10.1159/000357093 ◽

2014 ◽

Vol 132 (1) ◽

pp. 87-96 ◽

Cited By ~ 3

Author(s):

Hawk Kim ◽

Je-Hwan Lee ◽

Young-Don Joo ◽

Sung Hwa Bae ◽

Jung-Hee Lee ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Phase Ii ◽

Myeloid Leukemia ◽

Phase Ii Study ◽

Multicenter Phase ◽

Acute Myeloid

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Randomized phase II study of clofarabine versus clofarabine plus low-dose cytarabine (ara-C) for patients (pts) ≥ 60 years (yrs) with newly diagnosed acute myeloid leukemia (AML)

Journal of Clinical Oncology ◽

10.1200/jco.2005.23.16_suppl.6627 ◽

2005 ◽

Vol 23 (16_suppl) ◽

pp. 6627-6627 ◽

Cited By ~ 2

Author(s):

S. Faderl ◽

F. Ravandi-Kashani ◽

A. Ferrajoli ◽

Z. Estrov ◽

W. Wierda ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Phase Ii ◽

Myeloid Leukemia ◽

Low Dose ◽

Phase Ii Study ◽

Newly Diagnosed ◽

Randomized Phase Ii ◽

Low Dose Cytarabine ◽

Acute Myeloid

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A multicenter, phase II study of maintenance azacitidine in older patients with acute myeloid leukemia in complete remission after induction chemotherapy

American Journal of Hematology ◽

10.1002/ajh.24087 ◽

2015 ◽

Vol 90 (9) ◽

pp. 796-799 ◽

Cited By ~ 11

Author(s):

Patrick T. Griffin ◽

Rami S. Komrokji ◽

Carlos M. De Castro ◽

David A. Rizzieri ◽

Magda Melchert ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Complete Remission ◽

Induction Chemotherapy ◽

Phase Ii ◽

Older Patients ◽

Myeloid Leukemia ◽

Phase Ii Study ◽

Multicenter Phase ◽

Acute Myeloid

Download Full-text