1,3,4-Oxadiazole as a Potential Anti-Cancer Scaffold: A Review
2021 ◽
Vol 12
(4)
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pp. 5727-5744
Keyword(s):
1,3,4-oxadiazole is an aromatic heterocycle with –N=C=O- linkage. 1,3,4-oxadiazole derivatives possess remarkable biological properties; antimicrobial anti-inflammatory, anti-cancer, antitubercular, antioxidant, antiviral, and anti-diabetic. This scaffold is present in many marketed drugs, such as Raltegravir, Tiodazosin, Nesapidil, and Zibotentan. 1,3,4-oxadiazole derivatives have displayed significant anti-cancer potential with a diverse mode of actions viz. growth factors, enzymes, kinases, etc. The present review gives an overview of the anti-cancer potential of 1,3,4-oxadiazoles derivatives in cancer drug discovery and development from the last ten years.
2012 ◽
Vol 5
(6)
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pp. 557-565
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Keyword(s):
Keyword(s):
2003 ◽
Vol 12
(9)
◽
pp. 1577-1582
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Keyword(s):
2020 ◽
Vol 20
(20)
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pp. 1771-1771
Keyword(s):
2020 ◽
Vol 17
(9)
◽
pp. 1102-1116
2016 ◽
Vol 16
(10)
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pp. 1339-1352
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2019 ◽
2021 ◽
Vol 0
(0)
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pp. 0-0