scholarly journals Rhabdomyolysis after Hand Assisted Laparoscopic Donor Nephrectomy: Calgary’s experience

2019 ◽  
Vol 19 (2) ◽  
pp. 44-47
Author(s):  
Ryan Rochon ◽  
Mauricio Monroy ◽  
Serdar Yilmaz

Background:  Rhabdomyolysis is a post-operative complication resulting from skeletal muscle injury during the surgery.  The true incidence of rhabdomyolysis in laparoscopic living donor nephrectomy is unknown due to a paucity of evidence in the literature. Rhabdomyolysis can have serious short-term and long-term consequences for the living kidney donors. There have been a number of risk factors identified that may increase the risk of rhabdomyolysis. Materials and Methods: Our program has offered a hand assisted laparoscopic donor nephrectomy approach for our donors since 2001.We have performed 209 kidney transplants using this approach.  The institution’s database was searched for postoperative complications. Three donor patients with post-operative rhabdomyolysis were identified. Results: All three patients were young healthy males.  The operative times were all greater than four hours.  Fortunately, all three patients were recognized early and received treatment promptly.  Dialysis was not required and no long-term renal dysfunction occurred. Conclusion:  Rhabdomyolysis is an uncommon post-operative complication following hand assisted laparoscopic living donor nephrectomy.  We have a high index of suspicion for rhabdomyolysis to promptly recognize this rare but potentially serious complication after any operation lasting greater than 4 hours.  Creatinine Kinase levels have been implemented at our centre for all living kidney donors. Journal of Surgical Sciences (2015) Vol. 19 (2) : 44-47

2020 ◽  
Vol 34 (1) ◽  
pp. S41-S41
Author(s):  
Minh Sam Thai ◽  
Quy Thuan Chau ◽  
Khac Chuan Hoang ◽  
Xuan Thai Ngo ◽  
Trong Hien Nguyen ◽  
...  

2020 ◽  
Vol 18 (6) ◽  
pp. 682-688
Author(s):  
Hiroki Fukuhara ◽  
Takaaki Nawano ◽  
Akiko Kanda ◽  
Toshihide Tomosugi ◽  
Manabu Okada ◽  
...  

2007 ◽  
Vol 84 (1) ◽  
pp. 64-69 ◽  
Author(s):  
Marit Helen Andersen ◽  
Lars Mathisen ◽  
Marijke Veenstra ◽  
Ole ??yen ◽  
Bj??rn Edwin ◽  
...  

2002 ◽  
Vol 12 (3) ◽  
pp. 208-211 ◽  
Author(s):  
Douglas P. Slakey ◽  
Julie Cauvin Hahn ◽  
Ethan Rogers ◽  
Philippe M. Gauthier ◽  
Gilberto Ruiz-Deya ◽  
...  

Context Laparoscopic living donor nephrectomy has been shown to be a safe method for removing kidneys for transplantation, but concerns have been raised regarding safety and long-term kidney function. Objective To compare safety and long-term kidney function in hand-assisted laparoscopic, pure laparoscopic, and traditional open living donor nephrectomy. Method The charts of 48 patients with more than 1 year follow-up were reviewed. Thirty-four consecutive patients underwent laparoscopic live donor nephrectomy, and 14 had open donor nephrectomy. All kidneys functioned immediately at transplantation. In the laparoscopic group, 11 had the pure laparoscopic technique, and 23 patients had hand-assisted laparoscopic nephrectomy. Results Total operative and warm ischemic times were reduced with the hand-assisted technique when compared with pure laparoscopy. Operative and warm ischemic times were similar in open nephrectomy and hand-assisted laparoscopy. Long-term follow-up of serum creatinine levels revealed no significant differences between the 3 groups. Complication rates in the 3 groups were similar. Conclusion Laparoscopic donor nephrectomy appears to be comparable to open donor nephrectomy in terms of safety and long-term graft function.


2016 ◽  
Vol 43 (6) ◽  
pp. 389-396 ◽  
Author(s):  
Colin M.E. Halverson ◽  
Jackie Y. Wang ◽  
Michael Poulson ◽  
Jennifer Karlin ◽  
Megan Crowley-Matoka ◽  
...  

Background: Psychosocial data about living kidney donors have been collected for almost 5 decades now. To date, however, no study has provided any psychosocial follow-up of donors who developed a serious health problem such as end-stage renal disease (ESRD). Methods: Donors who developed ESRD were invited to participate in a qualitative interview if they met one or both of the inclusion criteria: (1) developed ESRD within 10 years of donating and/or (2) lacked health insurance at the time of donation. We contacted 38 individuals who met these criteria, and 22 participated (58%). Two were subsequently excluded from analysis. Results: Twenty qualitative interviews were analyzed. Five findings are described: (1) donors describe the decision-making process as spontaneous and fast; (2) donors describe lack of appreciation for the need for post-donation self-care; (3) donors do not regret donating despite the adverse outcome; (4) donors advise future donors to have in place emotional and physical support post donation; and (5) donors appreciate the opportunity to tell their story from being a living donor to living with ESRD, which virtually all perceive as 2 separate unrelated events. Conclusions: Most donors are positive about their donation decision and experience and would donate again, despite developing ESRD themselves. They propose some important changes to the decision-making and informed-consent processes. Our data are reassuring regarding lack of donor regret, but highlight the need for living donor transplant programs to ensure that living donors understand their long-term risks and receive appropriate life-long follow-up care to minimize these risks.


2019 ◽  
Author(s):  
Wolfgang Baar ◽  
Ulrich Goebel ◽  
Hartmut Buerkle ◽  
Bernd Jaenigen ◽  
Kai Kaufmann ◽  
...  

Abstract Background The beneficial effects of epidural analgesia (EDA) in terms of pain control and postoperative convalescence are widely known and led to a frequent use for patients who underwent living donor kidney nephrectomy. The objective of this study was to determine whether general anesthesia (GA) plus EDA compared to GA only, administered for living donor nephrectomy has effects on postoperative graft function in recipients. Methods In this monocentric, retrospective cohort analysis we analyzed the closed files of all consecutive donor- recipient pairs who underwent living donor kidney transplantations from 2008 to 2017. The outcome variable was delayed graft function (DGF), defined as at least one hemodialysis within seven days postoperatively, once hyperacute rejection, vascular or urinary tract complications were ruled out. Statistical analyses of continuous variables were calculated using the two-tail Student’s t test and Fisher exact test for categorical variables with a significance level of p<0.05, respectively. Results The study enclosed 291 consecutive living donor kidney transplantations. 99 kidney donors received epidural analgesia whereas 192 had no epidural analgesia. The groups showed balanced pretransplantational characteristics and comparable donors´ and recipients’ risk factors. 9 out of all 291 recipients needed renal replacement therapy (RRT) during the first 7 days due to delayed graft function; none of these donors received EDA. The observed rate of DGF in recipients whose kidney donors received epidural analgesia was significantly lower (0% vs. 4.6%; p=0.031). Conclusions In our cohort we observed a significantly lower rate of DGF when epidural analgesia for donor nephrectomy was administered. Due to restrictions of the study design this observation needs further confirmation by prospective studies.


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