scholarly journals Comparison of the efficacy of Solifenacin Succinate and Tolterodine for the treatment of overactive bladder syndrome

2017 ◽  
Vol 8 (2) ◽  
pp. 231-234
Author(s):  
Mohammad Monsur Hallaz ◽  
BH Nazma Yasmeen ◽  
Nadia Sultana ◽  
Mahfuza Akter ◽  
Nurul Alam Basher

Background : Overactive Bladder Syndrome(OAB) is not an uncommon problem. Although exact incidence of this disease in our country is not known but a significant number of people suffering from this disease seek treatment at the Urology department of different hospitals. At present two common antimuscarinic drug Solifenacin Succinate and Tolterodine are available in our country for the treatment of OAB.Objective : To compare the efficacy of Solifenacin Succinate and Tolterodine to treat OAB.Methodology : This hospital based randomized control trial was conducted in the Department of Urology, Dhaka Medical College Hospital, Dhaka and a private hospital from January 2009 to December 2010 to compare the efficacy of two new generation antimuscarinics, Solifenacin succinate and Tolterodine at their recommended doses for the treatment of OAB.Results : After 3 months of treatment it has clearly shown that Solifenacin is more effective in reducing OAB symptoms compared with extended release preparation of Tolterodine. This include statistically significant reduction in episodes of frequency, urgency, urge incontinence, nocturia and significant improvement of voided volume.Northern International Medical College Journal Vol.8(2) January 2017: 231-234

2012 ◽  
Vol 6 (2) ◽  
pp. 7-10
Author(s):  
Mohammad Murshed ◽  
Sabeena Shahnaz ◽  
Md. Abdul Malek

Isolation and identification of post operative hospital acquired infection was carried out from July 2008 to December 2008 in Holy Family Red Crescent Medical College Hospital (private hospital). The major pathogen of wound infection was E. coli. A total; of 120 samples were collected from the surrounding environment of post operative room like floor, bed sheets, instruments, dressing materials, catheter, nasogastric and endotracheal tube. E. coli (40%) was the predominant organism followed by S. aureus (24%). DNA fingerprinting analysis using pulsed field gel electreopheresis of XbaI restriction digested genomic DNA showed that clonal relatedness between the two clinical nd environmental isolates were 100%.DOI: http://dx.doi.org/10.3329/bjmm.v6i2.19369 Bangladesh J Med Microbiol 2012; 06(02): 7-10


2015 ◽  
Vol 5 (3) ◽  
pp. 157-160
Author(s):  
Halima Begum ◽  
Mahfuza Mazeda Rowshan ◽  
Sayeda Khanom ◽  
Shammin Haque ◽  
Farhana Afroze ◽  
...  

Background: Medically inappropriate, ineffective and economically inefficient use of drugs is very common in our country. About 40% or more drugs expenditure may be wasted through irrational prescribing and dispensing. The need for promoting rational use of drugs is not only because of economic considerations; also it is an essential element for achieving quality of the health and medical care for patients and the community. For this purpose a cross sectional study was carried out among the individuals attending the outpatient departments (OPD) of Medicine, Surgery, Gynecology & Obstetrics, Pediatrics, Orthopedics, Dermatology & Venereology, Ophthalmology and Otolaryngology of two tertiary care teaching hospitals of Dhaka, Bangladesh.Objective: To observe the prescribing pattern in outpatient departments of two tertiary care teaching hospitals (Dhaka) by using World Health Organization (WHO) core prescribing indicators.Materials and Methods: Six hundred prescriptions of patients attending the OPD of Medicine, Surgery, Gynecology & Obstetrics, Pediatrics, Orthopedics, Dermatology & Venereology, Ophthalmology and Otolaryngology of Enam Medical College Hospital (private hospital) and Sir Salimullah Medical College Hospital (public hospital) were collected randomly on working days from April to September 2014. Then the prescriptions were analyzed by following the “Prescribing indicators form” as recommended by the International Organization of Rational Use of Drugs (INRUD)/WHO.Results: Average number of drugs per prescription was significantly high (3.07 in public hospital and 3.00 in private hospital). Generic prescribing was significantly lower in private hospital (4.00%) than that in public hospital (21.00%). Antibiotic prescription was higher in private hospital (42.35%). Injection prescribed in public hospital was 5.74% whereas 5.66% in private hospital. Drugs prescribed from Essential Drug List of Bangladesh were less in both the hospitals (42.85% in public hospital and 40.06% in private hospital).Conclusion: Average number of drugs per prescription was higher in both hospitals. Generic prescribing was lower in private hospital and prescribing from EDL was low in both hospitals.J Enam Med Col 2015; 5(3): 157-160


2009 ◽  
Vol 20 (12) ◽  
pp. 1431-1438 ◽  
Author(s):  
Peter K. Sand ◽  
Roger R. Dmochowski ◽  
Norman R. Zinner ◽  
David R. Staskin ◽  
Rodney A. Appell

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