scholarly journals Gambaran Klinis Stomatitis Aftosa Rekuren pada Pasien dengan Infeksi Human Immunodeficiency Virus (Laporan Kasus)

2019 ◽  
Vol 6 (2) ◽  
Author(s):  
Nurfianti Nurfianti ◽  
Siti Aliyah Pradono

Recurrent oral ulceration usually induced pain and influence patient’s quality of life. Reccurent Aphthous Stomatitis (RAS) is a common disorder with recurring ulcers, affecting the oral mucosa, painful and no other signs of systemic disease. Human Immunodeficiency Virus (HIV) is considered as a predisposing factor for RAS. Lesion of RAS associated with HIV, usually more severe, longer lasting to healing and non specific clinical features. This case report describe clinical features of recurrent oral ulceration in HIV patient.  A 23 year old female came with complaint oral ulceration in soft palate and tongue since 2 months ago. Patient was diagnosis HIV since seven years ago. Several examinations were done to explore possibility of opportunist infection in HIV patient. Intra oral examination showed regular ulcer, with yellowish base, surrounding erythematous halo. The locations of ulcer were in labial mucosa, dorsum and ventral of the tongue, and soft palate. Ulceration in keratinized mucosa and non keratinized mucosa, gives un-specific features mimicking Tuberculous oral ulcer but in this case there was no indurations on all ulcer. Based on anamnesis and clinical examination, the diagnosis of this case is RAS with differential diagnosis of Tuberculous oral ulcer. The therapy given was gold standard of RAS, the outcome was successful without TB therapy. RAS on HIV Patient can give unspecific clinical features, mimicking oral manifestation of opportunist infection commonly occurred in HIV patient.

2015 ◽  
Vol 3 (3) ◽  
pp. 130-135
Author(s):  
Rakesh Basavareddy ◽  
Asha Basavareddy ◽  
Shimoga Laxman Ravi ◽  
Bilagumba Ramu Kiran ◽  
Gadwalkar R. Srikant

Abstract Background and Objectives: Tuberculosis (TB) and the human immunodeficiency virus (HIV) infection have reached epidemic proportions in our country. This study was undertaken to know the seroprevalence of HIV infection among TB patients and to evaluate the various clinical features of TB in seropositive and seronegative patients. This study was undertaken in Vijayanagara Institute of Medical Sciences, Bellary. It was cross-sectional comparative observational study conducted from December 2010 to May 2012. Materials and Methods: A total of 100 consecutive patients diagnosed with TB satisfying inclusion criteria were selected for the study. All patients went through a detailed evaluation along with testing for HIV seroprevalence. Chi-square and Student’s t-tests used to find the significance between two groups. Results: The overall HIV seroprevalence among TB patients was 8%. Seroprevalence was highest in the age group between 31 and 40 years at 29.41% (odds ratio [OR] = 11.11, P = 0.003). It was found that seropositive TB patients were more likely to present with significant weight loss (OR = 19.25, P= 0.000), and have lymphadenopathy OR = 13.24, P = 0.002) and oral candidiasis (OR = 49.44, P = 0.000) on examination. Bilateral chest radiographic involvement (OR = 57.40, P = 0.000) and the disseminated variety of the disease (OR = 29.67, P = 0.001) are also more probable. Conclusions: Human immunodeficiency virus seroprevalence is quite high among TB patients in Bellary. During the evaluation of TB patients, the possibility of HIV co-infection should be kept in mind, and thus adequate knowledge of the likely clinical features is absolutely necessary.


2019 ◽  
Vol 7 ◽  
pp. 2050313X1982961
Author(s):  
Connie Zhang ◽  
Megan A Sander

A 58-year-old woman from Zimbabwe, with a history of untreated human immunodeficiency virus, presented with leonine facies and a diffuse rash. The rash occurred in the context of a 1-year history of constitutional symptoms and cognitive decline. Laboratory investigations confirmed that her human immunodeficiency virus had progressed to acquired immunodeficiency syndrome. Through imaging, tissue biopsies, and polymerase chain reaction, a diagnosis of disseminated histoplasmosis was made. Since there was no history of travel and histoplasmosis is not locally endemic, the patient likely contracted this fungal infection more than 7 years ago, while living in Africa. We speculate that the histoplasmosis remained latent until her immune system began to decline. The work-up and management of this rare cutaneous presentation of a systemic disease, which should be added to the list of “great mimickers” in dermatology, are discussed.


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