scholarly journals IN SILICO DRUG EVALUATION AND DRUG RESEARCH OF BIOACTIVE MOLECULE METHYL 4-BROMO-2-FLUOROBENZOATE

Author(s):  
Maria JULİE ◽  
T. PRABHU ◽  
Fazılath Basha ASİF ◽  
S. MUTHU
2018 ◽  
Vol 16 (6) ◽  
pp. 786-848 ◽  
Author(s):  
Agostinho Lemos ◽  
Rita Melo ◽  
Antonio Jose Preto ◽  
Jose Guilherme Almeida ◽  
Irina Sousa Moreira ◽  
...  

2021 ◽  
Vol 22 (16) ◽  
pp. 8657
Author(s):  
Teruki Nii ◽  
Yoshiki Katayama

This review aims to show case recent regenerative medicine based on biomaterial technologies. Regenerative medicine has arousing substantial interest throughout the world, with “The enhancement of cell activity” one of the essential concepts for the development of regenerative medicine. For example, drug research on drug screening is an important field of regenerative medicine, with the purpose of efficient evaluation of drug effects. It is crucial to enhance cell activity in the body for drug research because the difference in cell condition between in vitro and in vivo leads to a gap in drug evaluation. Biomaterial technology is essential for the further development of regenerative medicine because biomaterials effectively support cell culture or cell transplantation with high cell viability or activity. For example, biomaterial-based cell culture and drug screening could obtain information similar to preclinical or clinical studies. In the case of in vivo studies, biomaterials can assist cell activity, such as natural healing potential, leading to efficient tissue repair of damaged tissue. Therefore, regenerative medicine combined with biomaterials has been noted. For the research of biomaterial-based regenerative medicine, the research objective of regenerative medicine should link to the properties of the biomaterial used in the study. This review introduces regenerative medicine with biomaterial.


2008 ◽  
Vol 61 (3) ◽  
pp. 205-206 ◽  
Author(s):  
Til Stürmer ◽  
Kenneth J. Rothman ◽  
Jerry Avorn

2020 ◽  
Vol 118 (10) ◽  
pp. 2596-2611 ◽  
Author(s):  
Michelangelo Paci ◽  
Elisa Passini ◽  
Aleksandra Klimas ◽  
Stefano Severi ◽  
Jari Hyttinen ◽  
...  

2004 ◽  
Vol 76 (5) ◽  
pp. 907-914 ◽  
Author(s):  
B. Testa ◽  
A.-L. Balmat ◽  
Anthony Long

The paper begins with a discussion of the needs and goals of metabolic predictions in early drug research. Major difficulties toward this objective are examined, mainly the various substrate and product selectivities characteristic of drug metabolism. In a second part, we classify and summarize the major in silico methods used to predict drug metabolism. A discrimination is thus made between “local ”and “global ”systems. In the last part of the paper, the program METEOR is presented and evaluated using the published metabolic data of 10 substrates.


2018 ◽  
Vol 16 (6) ◽  
pp. 664-725 ◽  
Author(s):  
Farahnaz Rezaei Makhouri ◽  
Jahan B. Ghasemi

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