scholarly journals Longitudinal Bedside Assessments of Brain Networks in Disorders of Consciousness: Case Reports From the Field

2018 ◽  
Vol 9 ◽  
Author(s):  
Corinne A. Bareham ◽  
Judith Allanson ◽  
Neil Roberts ◽  
Peter J. A. Hutchinson ◽  
John D. Pickard ◽  
...  
Brain ◽  
2017 ◽  
Vol 140 (8) ◽  
pp. 2120-2132 ◽  
Author(s):  
Srivas Chennu ◽  
Jitka Annen ◽  
Sarah Wannez ◽  
Aurore Thibaut ◽  
Camille Chatelle ◽  
...  

2017 ◽  
Vol 39 (1) ◽  
pp. 89-103 ◽  
Author(s):  
Carol Di Perri ◽  
Enrico Amico ◽  
Lizette Heine ◽  
Jitka Annen ◽  
Charlotte Martial ◽  
...  

2014 ◽  
Vol 10 (10) ◽  
pp. e1003887 ◽  
Author(s):  
Srivas Chennu ◽  
Paola Finoia ◽  
Evelyn Kamau ◽  
Judith Allanson ◽  
Guy B. Williams ◽  
...  

2018 ◽  
Author(s):  
Jennifer Rizkallah ◽  
Jitka Annen ◽  
Julien Modolo ◽  
Olivia Gosseries ◽  
Pascal Benquet ◽  
...  

AbstractIncreasing evidence links disorders of consciousness (DOC) with disruptions in functional connectivity between distant brain areas. However, to which extent the balance of brain network segregation and integration is modified in DOC patients remains unclear. Using high-density electroencephalography (EEG), the objective of our study was to characterize the local and global topological changes of DOC patients’ functional brain networks.Resting state high-density-EEG data were collected and analyzed from 82 participants: 61 DOC patients recovering from coma with various levels of consciousness (EMCS (n=6), MCS+ (n=29), MCS- (n=17) and UWS (n=9)), and 21 healthy subjects (i.e., controls). Functional brain networks in five different EEG frequency bands and the broadband signal were estimated using an EEG connectivity approach at the source level. Graph theory-based analyses were used to evaluate group differences between healthy volunteers and patient groups.Results showed that networks in DOC patients are characterized by impaired global information processing (network integration) and increased local information processing (network segregation) as compared to controls. The large-scale functional brain networks had integration decreasing with lower level of consciousness.


2021 ◽  
Vol 69 (6) ◽  
pp. 31-42
Author(s):  
Alina O. Ivanova ◽  
Ekaterina A. Kondratyeva ◽  
Maria I. Yarmolinskaya ◽  
Elena V. Misharina ◽  
Margarita S. Florova ◽  
...  

According to the modern classification system, chronic disorders of consciousness are defined as an altered state of consciousness that develops after coma and is accompanied by the restoration of wakefulness without the complete recovery of conscious activity for more than 28 days after traumatic brain injury. Clinical cases of chronic chronic disorders of consciousness development in women after surgical interventions related to various obstetrical and gynecological pathologies, as well as after routine surgical interventions for comorbid somatic pathology, are of particular interest to obstetricians and gynecologists. In the presented chronic chronic disorders of consciousness related clinical cases of operations for ectopic pregnancy, as well as consequences of elective surgery for gallstone disease, the development of hypo- and normogonadotropic ovarian insufficiency associated with chronic disorders of consciousness is described. The characteristics of the thyroid status, adrenocorticotropic function, and vitamin D levels are given. Further in-depth examination and accumulation of data on patients with chronic disorders of consciousness may provide an opportunity to determine informative markers for prognostication of outcomes, as well as to develop new effective approaches to consciousness rehabilitation in this category of patients.


2011 ◽  
Vol 21 (1) ◽  
pp. 5-14
Author(s):  
Christy L. Ludlow

The premise of this article is that increased understanding of the brain bases for normal speech and voice behavior will provide a sound foundation for developing therapeutic approaches to establish or re-establish these functions. The neural substrates involved in speech/voice behaviors, the types of muscle patterning for speech and voice, the brain networks involved and their regulation, and how they can be externally modulated for improving function will be addressed.


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