scholarly journals Language Mapping Using Stereo Electroencephalography: A Review and Expert Opinion

2021 ◽  
Vol 15 ◽  
Author(s):  
Olivier Aron ◽  
Jacques Jonas ◽  
Sophie Colnat-Coulbois ◽  
Louis Maillard
Keyword(s):  
Network Architecture ◽  
Temporal Cortex ◽  
Whole Body ◽  
Language Mapping ◽  
Language Deficit ◽  
Depth Electrodes ◽  
Ventral Temporal Cortex ◽  
New Research ◽  
Temporal Language ◽  
Methodological Aspects

Stereo-electroencephalography (sEEG) is a method that uses stereotactically implanted depth electrodes for extra-operative mapping of epileptogenic and functional networks. sEEG derived functional mapping is achieved using electrical cortical stimulations (ECS) that are currently the gold standard for delineating eloquent cortex. As this stands true especially for primary cortices (e.g., visual, sensitive, motor, etc.), ECS applied to higher order brain areas determine more subtle behavioral responses. While anterior and posterior language areas in the dorsal language stream seem to share characteristics with primary cortices, basal temporal language area (BTLA) in the ventral temporal cortex (VTC) behaves as a highly associative cortex. After a short introduction and considerations about methodological aspects of ECS using sEEG, we review the sEEG language mapping literature in this perspective. We first establish the validity of this technique to map indispensable language cortices in the dorsal language stream. Second, we highlight the contrast between the growing empirical ECS experience and the lack of understanding regarding the fundamental mechanisms underlying ECS behavioral effects, especially concerning the dispensable language cortex in the VTC. Evidences for considering network architecture as determinant for ECS behavioral response complexities are discussed. Further, we address the importance of designing new research in network organization of language as this could enhance ECS ability to map interindividual variability, pathology driven reorganization, and ultimately identify network resilience markers in order to better predict post-operative language deficit. Finally, based on a whole body of available studies, we believe there is strong evidence to consider sEEG as a valid, safe and reliable method for defining eloquent language cortices although there have been no proper comparisons between surgical resections with or without extra-operative or intra-operative language mapping.

fMRI Responses to Video and Point-Light Displays of Moving Humans and Manipulable Objects

2003 ◽  
Vol 15 (7) ◽  
pp. 991-1001 ◽  
Author(s):  
Michael S. Beauchamp ◽  
Kathryn E. Lee ◽  
James V. Haxby ◽  
Alex Martin
Keyword(s):  
Visual Motion ◽  
Temporal Cortex ◽  
Body Motion ◽  
Whole Body ◽  
Middle Temporal Gyrus ◽  
Stimulus Category ◽  
Video Clips ◽  
Different Types ◽  
Ventral Temporal Cortex ◽  
Point Light

We used fMRI to study the organization of brain responses to different types of complex visual motion. In a rapid eventrelated design, subjects viewed video clips of humans performing different whole-body motions, video clips of manmade manipulable objects (tools) moving with their characteristic natural motion, point-light displays of human whole-body motion, and point-light displays of manipulable objects. The lateral temporal cortex showed strong responses to both moving videos and moving point-light displays, supporting the hypothesis that the lateral temporal cortex is the cortical locus for processing complex visual motion. Within the lateral temporal cortex, we observed segregated responses to different types of motion. The superior temporal sulcus (STS) responded strongly to human videos and human point-light displays, while the middle temporal gyrus (MTG) and the inferior temporal sulcus responded strongly to tool videos and tool point-light displays. In the ventral temporal cortex, the lateral fusiform responded more to human videos than to any other stimulus category while the medial fusiform preferred tool videos. The relatively weak responses observed to point-light displays in the ventral temporal cortex suggests that form, color, and texture (present in video but not point-light displays) are the main contributors to ventral temporal activity. In contrast, in the lateral temporal cortex, the MTG responded as strongly to point-light displays as to videos, suggesting that motion is the key determinant of response in the MTG. Whereas the STS responded strongly to point-light displays, it showed an even larger response to video displays, suggesting that the STS integrates form, color, and motion information.

Stereoelectroencephalographic language mapping of the basal temporal cortex predicts postoperative naming outcome

2021 ◽  
pp. 1-11
Author(s):  
Chifaou Abdallah ◽  
Hélène Brissart ◽  
Sophie Colnat-Coulbois ◽  
Ludovic Pierson ◽  
Olivier Aron ◽  
...  
Keyword(s):  
Temporal Lobe ◽  
Verbal Fluency ◽  
Temporal Cortex ◽  
Visual Object ◽  
Drug Resistant ◽  
Language Mapping ◽  
Individual Level ◽  
Language Outcome ◽  
Temporal Lobe Resection ◽  
The Individual

OBJECTIVEIn drug-resistant temporal lobe epilepsy (TLE) patients, the authors evaluated early and late outcomes for decline in visual object naming after dominant temporal lobe resection (TLR) according to the resection status of the basal temporal language area (BTLA) identified by cortical stimulation during stereoelectroencephalography (SEEG).METHODSTwenty patients who underwent SEEG for drug-resistant TLE met the inclusion criteria. During language mapping, a site was considered positive when stimulation of two contiguous contacts elicited at least one naming impairment during two remote sessions. After TLR ipsilateral to their BTLA, patients were classified as BTLA+ when at least one positive language site was resected and as BTLA− when all positive language sites were preserved. Outcomes in naming and verbal fluency tests were assessed using pre- and postoperative (means of 7 and 25 months after surgery) scores at the group level and reliable change indices (RCIs) for clinically meaningful changes at the individual level.RESULTSBTLA+ patients (n = 7) had significantly worse naming scores than BTLA− patients (n = 13) within 1 year after surgery but not at the long-term evaluation. No difference in verbal fluency tests was observed. When RCIs were used, 5 of 18 patients (28%) had naming decline within 1 year postoperatively (corresponding to 57% of BTLA+ and 9% of BTLA− patients). A significant correlation was found between BTLA resection and naming decline.CONCLUSIONSBTLA resection is associated with a specific and early naming decline. Even if this decline is transient, naming scores in BTLA+ patients tend to remain lower compared to their baseline. SEEG mapping helps to predict postoperative language outcome after dominant TLR.

scholarly journals Responses of Anterior Superior Temporal Polysensory (STPa) Neurons to “Biological Motion” Stimuli

1994 ◽  
Vol 6 (2) ◽  
pp. 99-116 ◽  
Author(s):  
M. W. Oram ◽  
D. I. Perrett
Keyword(s):  
Biological Motion ◽  
Temporal Cortex ◽  
The Body ◽  
Body Motion ◽  
Whole Body ◽  
Global Pattern ◽  
Lighting Conditions ◽  
Specific Direction ◽  
Direction Of Movement ◽  
Light Stimuli

Cells have been found in the superior temporal polysensory area (STPa) of the macaque temporal cortex that are selectively responsive to the sight of particular whole body movements (e.g., walking) under normal lighting. These cells typically discriminate the direction of walking and the view of the body (e.g., left profile walking left). We investigated the extent to which these cells are responsive under “biological motion” conditions where the form of the body is defined only by the movement of light patches attached to the points of limb articulation. One-third of the cells (25/72) selective for the form and motion of walking bodies showed sensitivity to the moving light displays. Seven of these cells showed only partial sensitivity to form from motion, in so far as the cells responded more to moving light displays than to moving controls but failed to discriminate body view. These seven cells exhibited directional selectivity. Eighteen cells showed statistical discrimination for both direction of movement and body view under biological motion conditions. Most of these cells showed reduced responses to the impoverished moving light stimuli compared to full light conditions. The 18 cells were thus sensitive to detailed form information (body view) from the pattern of articulating motion. Cellular processing of the global pattern of articulation was indicated by the observations that none of these cells were found sensitive to movement of individual limbs and that jumbling the pattern of moving limbs reduced response magnitude. A further 10 cells were tested for sensitivity to moving light displays of whole body actions other than walking. Of these cells 5/10 showed selectivity for form displayed by biological motion stimuli that paralleled the selectivity under normal lighting conditions. The cell responses thus provide direct evidence for neural mechanisms computing form from nonrigid motion. The selectivity of the cells was for body view, specific direction, and specific type of body motion presented by moving light displays and is not predicted by many current computational approaches to the extraction of form from motion.

scholarly journals How learning to read affects the function and structure of ventral temporal cortex

2019 ◽  
Vol 19 (10) ◽  
pp. 4c
Author(s):  
Kalanit Grill-Spector ◽  
Marisa Nordt ◽  
Vaidehi Natu ◽  
Jesse Gomez ◽  
Brianna Jeska ◽  
...  
Keyword(s):  
Temporal Cortex ◽  
Learning To Read ◽  
Ventral Temporal Cortex

scholarly journals Near-perfect prediction of reaction time for face gender judgments based on activity in ventral temporal cortex

2015 ◽  
Vol 15 (12) ◽  
pp. 753
Author(s):  
Kalanit Grill-Spector ◽  
Kevin Weiner ◽  
Nikolaus Kriegeskorte ◽  
Kendrick Kay
Keyword(s):  
Reaction Time ◽  
Temporal Cortex ◽  
Ventral Temporal Cortex
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