Oral language of school-aged children born pretermaturely: a population-based analysis from Madeira Island, Portugal

Premature birth and low birth weight are very important factors in neurodevelopment. Current research in this population focuses on children born prematurely, with no underlying complications in the post-natal period, who are likely to develop specific disorders with their language development and consequently with their learning capabilities too. This study aims to analyse the oral language skills of prematurely born children in comparison to their school-aged peers. The children were assessed in the respective schools, 27 preterm children (16 under 32 weeks and 11 with 32 or more weeks of gestation) and 49 term paired by gender, age, and school year. Tests including simple and complex structures for assessing semantics, morphosyntax, and phonology were used, as well as a test of verbal memory. Preterm born children, regardless of their prematurity grade, showed significantly lower results than their peers, and more than a half of them, 52%, presented low scores in all language tests simultaneously, showing an important language deficit. In contrast, in the term born children group only 14% showed low scores simultaneously in all tests. Verbal memory ability proved to be lower than that of their term peers, regardless of the gestational age and birth weight of preterm children. As a result of this analysis we consider that the evaluation of the linguistic development of these children, even in cases of moderate to late prematurity, should be monitored in order to identify earlier the existence of deficits and prevent psychosocial and learning problems.

“Slowly But Sure”: A Language Deficit of a Child with Down Syndrome

This is a case study research in this paper reports on findings from the case study (syntactic and morphological) in an individual diagnosed with a genetic disorder, Down Syndrome (DS), that affect language development without getting the help of any official therapists. We perform pragmatic and phonological analyses alongside morphology and syntactic analyses on data collected from studying documents, observation, and interview results. The qualitative descriptive linguistic method is used in this study to provide a detailed description. The result shows some deficits performed by the DS caused by articulatory limitation, difficulty to follow some words in long statements, and difficulty to respond to the topic that he has not known before.

A Woman With Headaches and a Tumefactive Brain Lesion

A 65-year-old woman sought care for a 6-month history of confusion and emotional disturbance that was initially ascribed to stress. She then had development of headaches over several weeks, which prompted brain magnetic resonance imaging with contrast. Imaging showed a mass emanating bilaterally from the splenium of the corpus callosum with heterogeneous T1 postgadolinium enhancement. Neurologic examination indicated left homonymous hemianopia, but she was otherwise normal. She had neither alexia nor other language deficit that may appear with a splenial corpus callosum lesion. A biopsy of the brain mass was performed. Histologic analysis of the biopsy specimen revealed glioblastoma multiforme. Corticosteroid treatment was prescribed, which relieved her headache. Radiation therapy and chemotherapy (temozolomide) were recommended. No further follow-up information was available. In neurologic clinical practice, a large corpus callosum–based lesion is sometimes encountered. The localization of such lesions is not specific for any one diagnosis, but radiologic characteristics can aid clinical decision making. Although the radiologic appearance of a lesion spreading out into both hemispheres from the corpus callosum can indicate butterfly glioma, the differential diagnosis also includes tumefactive demyelinating disease and lymphoma, which can also have a callosal localization and produce mass effect.

Improved morpho-syntax in discourse following intensive voice treatment in Parkinson's disease: Secondary outcome variables from a Randomized Controlled Trial (RCT)

It is well established that voice is disordered in nearly 90% of individuals with Parkinsons disease (PD). Given the role of voice in language expression, we pose that optimizing vocal function may lead to improved language production. Verb production is an area of language deficit in PD, particularly for verbs associated with an individuals location of impairment (upper vs. lower limbs). It is thought that damage to the motor system, given its connection to action verbs, underlies this lexical effect. If this is the case, then treatment improving vocal motor function may also improve access to verbs. Nineteen participants with PD underwent Lee Silverman Voice Treatment (LSVT LOUD), a 4-week intensive voice treatment (TXPD), in an IRB-approved randomized controlled voice treatment trial. Language production was contrasted with 20 untreated PD (UNTXPD) and 20 age-matched neurotypical control participants. Each provided 1-minute picture description narratives at baseline and after 4-weeks. Pre-post treatment within- and between-group comparisons identified effects of assessment time point and isolated treatment effects in the TXPD relative to UNTXPD and Controls. Given the intervention, the TXPD group demonstrated a significant increase in loudness during the picture description, as well as increased utterance length, diversity of word types used, verbs per utterance, and lexical density.

Multilingualism for Global Solutions and a Better World

This article examines the significance of multilingualism in finding global solutions and creating a better world. Language learning and multilingualism in the individual are discussed. The role of multilingualism in effectively addressing complex global issues is described. The nature of language skills and cultural knowledge in the individual and within international organizations is analyzed in terms of both policy structure and crisis communication, including the COVID-19 global pandemic, along with a brief overview of multilingualism in international business organizations. The US foreign language deficit is briefly discussed. Perspectives on foreign language education for a better world are provided, as are possibilities for increasing multilingualism for a better world.

Cosmopolitanism and Multilingualism in a Globalized World: Perspectives on the Lack of Foreign Language Learning in the US

Although cosmopolitanism has a long history, it has become even more relevant in the global era and, especially, since the COVID-19 global pandemic has made communication and understanding across cultures more important than ever. Multilingualism is the essential cosmopolitan skill and tool, empowering those who are proficient in one or more additional languages to understand, and to communicate and interact with others more effectively. The United States suffers from a foreign language deficit, and there is an urgent need to build both motivation and interest in other languages along with sustainable skills in other languages in the US. Steps to effectively address this deficit include prioritizing language learning and use, and providing the opportunity to all interested students to learn one or more additional languages.

FOXG1 Gene and Its Related Phenotypes

FOXG1 is an important transcriptional repressor found in cell precursor of the ventricular region and in neurons in the early stage of differentiation during the development of the nervous epithelium in the cerebrum and optical formation. Mutations involving FOXG1 gene have been described first in subjects with congenital Rett syndrome. They can cause seizure, delayed psychomotor development, language disorders, and autism. FOXG1 deletions or intragenic mutations also determinate reduction in head circumference, structural defects in the corpus callosum, abnormal movements, especially choreiform, and intellectual retardation with no speech. Patients with duplications of 14q12 present infantile spasms and have subsequent intellectual disability with autistic features, head circumference in the normal range, and regular aspect of corpus callosum. Clinical characteristics of patients with FOXG1 variants include growth deficit after birth associated with microcephaly, facial dysmorphisms, important delay with no language, deficit in social interaction like autism, sleep disorders, stereotypes, including dyskinesia, and seizures. In these patients, it is not characteristic a history of loss of acquired skills.

BOOK REVIEW Book Author: Kathleen Stein-Smith. Book title: The U.S. Foreign Language Deficit: Strategies for Maintaining a Competitive Edge in a Globalized World. Year of Publication: (2016). Publisher: Fairleigh Dickinson University Teaneck, New Jersey, USA. Book pages: 123 pp. Book ISBN 978-3-319-34158-3

Kathleen Stein-Smith’s The U.S. Foreign Language Deficit: Strategies for Maintaining a Competitive Edge in a Globalized World is an attempt to outline a comprehensive and organized model for one of the recent trends in the field of teaching language and the importance of language.

Language Mapping Using Stereo Electroencephalography: A Review and Expert Opinion

Stereo-electroencephalography (sEEG) is a method that uses stereotactically implanted depth electrodes for extra-operative mapping of epileptogenic and functional networks. sEEG derived functional mapping is achieved using electrical cortical stimulations (ECS) that are currently the gold standard for delineating eloquent cortex. As this stands true especially for primary cortices (e.g., visual, sensitive, motor, etc.), ECS applied to higher order brain areas determine more subtle behavioral responses. While anterior and posterior language areas in the dorsal language stream seem to share characteristics with primary cortices, basal temporal language area (BTLA) in the ventral temporal cortex (VTC) behaves as a highly associative cortex. After a short introduction and considerations about methodological aspects of ECS using sEEG, we review the sEEG language mapping literature in this perspective. We first establish the validity of this technique to map indispensable language cortices in the dorsal language stream. Second, we highlight the contrast between the growing empirical ECS experience and the lack of understanding regarding the fundamental mechanisms underlying ECS behavioral effects, especially concerning the dispensable language cortex in the VTC. Evidences for considering network architecture as determinant for ECS behavioral response complexities are discussed. Further, we address the importance of designing new research in network organization of language as this could enhance ECS ability to map interindividual variability, pathology driven reorganization, and ultimately identify network resilience markers in order to better predict post-operative language deficit. Finally, based on a whole body of available studies, we believe there is strong evidence to consider sEEG as a valid, safe and reliable method for defining eloquent language cortices although there have been no proper comparisons between surgical resections with or without extra-operative or intra-operative language mapping.