scholarly journals Molecular Coevolution of Neuropeptides Gonadotropin-Releasing Hormone and Kisspeptin with their Cognate G Protein-Coupled Receptors

2012 ◽  
Vol 6 ◽  
Author(s):  
Dong-Kyu Kim ◽  
Eun Bee Cho ◽  
Mi Jin Moon ◽  
Sumi Park ◽  
Jong-Ik Hwang ◽  
...  
2012 ◽  
Vol 227 (6) ◽  
pp. 2492-2501 ◽  
Author(s):  
Sayomi Higa-Nakamine ◽  
Noriko Maeda ◽  
Seikichi Toku ◽  
Tomoko Yamamoto ◽  
Matee Yingyuenyong ◽  
...  

2002 ◽  
Vol 30 (4) ◽  
pp. 428-432 ◽  
Author(s):  
E. W. Hillhouse ◽  
H. Randeva ◽  
G. Ladds ◽  
D. Grammatopoulos

Corticotropin-releasing hormone (CRH) and related peptides (urocortins, sauvagine, urotensin) play a central role in the co-ordination of autonomic, behavioural, cardiovascular, immune and endocrine responses to stressful stimuli. Their actions are mediated through activation of two types of G-protein-coupled receptors encoded by separate genes. In this review we focus on the diverse structural and functional characteristics of the family of CRH-like peptides and their receptors.


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