scholarly journals Structure-Activity Investigation of a G Protein-Biased Agonist Reveals Molecular Determinants for Biased Signaling of the D2 Dopamine Receptor

2018 ◽  
Vol 10 ◽  
Author(s):  
Lani S. Chun ◽  
Rakesh H. Vekariya ◽  
R. Benjamin Free ◽  
Yun Li ◽  
Da-Ting Lin ◽  
...  
Keyword(s):  
Dopamine Receptor ◽  
G Protein ◽  
D2 Dopamine Receptor ◽  
Structure Activity ◽  
Molecular Determinants ◽  
Biased Signaling ◽  
Biased Agonist

scholarly journals Discovery and Characterization of a G Protein–Biased Agonist That Inhibits β-Arrestin Recruitment to the D2 Dopamine Receptor

2014 ◽  
Vol 86 (1) ◽  
pp. 96-105 ◽  
Author(s):  
R. Benjamin Free ◽  
Lani S. Chun ◽  
Amy E. Moritz ◽  
Brittney N. Miller ◽  
Trevor B. Doyle ◽  
...  
Keyword(s):  
Dopamine Receptor ◽  
G Protein ◽  
D2 Dopamine Receptor ◽  
Biased Agonist

scholarly journals Structure of a D2 dopamine receptor–G-protein complex in a lipid membrane

Nature ◽  
2020 ◽  
Vol 584 (7819) ◽  
pp. 125-129 ◽  
Author(s):  
Jie Yin ◽  
Kuang-Yui M. Chen ◽  
Mary J. Clark ◽  
Mahdi Hijazi ◽  
Punita Kumari ◽  
...  
Keyword(s):  
Dopamine Receptor ◽  
G Protein ◽  
Protein Complex ◽  
Lipid Membrane ◽  
D2 Dopamine Receptor

scholarly journals Discovery of G Protein-Biased D2 Dopamine Receptor Partial Agonists

2016 ◽  
Vol 59 (23) ◽  
pp. 10601-10618 ◽  
Author(s):  
Xin Chen ◽  
John D. McCorvy ◽  
Matthew G. Fischer ◽  
Kyle V. Butler ◽  
Yudao Shen ◽  
...  
Keyword(s):  
Dopamine Receptor ◽  
G Protein ◽  
D2 Dopamine Receptor ◽  
Partial Agonists

scholarly journals Neuronal Calcium Sensor-1 Binds the D2 Dopamine Receptor and G-protein-coupled Receptor Kinase 1 (GRK1) Peptides Using Different Modes of Interactions

2015 ◽  
Vol 290 (30) ◽  
pp. 18744-18756 ◽  
Author(s):  
Sravan Pandalaneni ◽  
Vijaykumar Karuppiah ◽  
Muhammad Saleem ◽  
Lee P. Haynes ◽  
Robert D. Burgoyne ◽  
...  
Keyword(s):  
Dopamine Receptor ◽  
G Protein ◽  
Calcium Sensor ◽  
Receptor Kinase ◽  
D2 Dopamine Receptor ◽  
G Protein Coupled Receptor ◽  
Neuronal Calcium Sensor ◽  
G Protein Coupled

scholarly journals G Protein Beta 5 Is Targeted to D2-Dopamine Receptor-Containing Biochemical Compartments and Blocks Dopamine-Dependent Receptor Internalization

PLoS ONE ◽  
2014 ◽  
Vol 9 (8) ◽  
pp. e105791 ◽  
Author(s):  
J. Christopher Octeau ◽  
Joseph M. Schrader ◽  
Ikuo Masuho ◽  
Meenakshi Sharma ◽  
Christopher Aiudi ◽  
...  
Keyword(s):  
Dopamine Receptor ◽  
G Protein ◽  
Receptor Internalization ◽  
D2 Dopamine Receptor
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