scholarly journals The Role of Human Aldo-Keto Reductases in the Metabolic Activation and Detoxication of Polycyclic Aromatic Hydrocarbons: Interconversion of PAH Catechols and PAH o-Quinones

2012 ◽  
Vol 3 ◽  
Author(s):  
Li Zhang ◽  
Yi Jin ◽  
Meng Huang ◽  
Trevor M. Penning
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Aromatic Hydrocarbons ◽  
Metabolic Activation ◽  
Polycyclic Aromatic

Role of Cytochrome P4501 Family Members in the Metabolic Activation of Polycyclic Aromatic Hydrocarbons in Mouse Epidermis

2004 ◽  
Vol 17 (12) ◽  
pp. 1667-1674 ◽  
Author(s):  
Heather E. Kleiner ◽  
Suryanarayana V. Vulimiri ◽  
William B. Hatten ◽  
Melissa J. Reed ◽  
Daniel W. Nebert ◽  
...  
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Aromatic Hydrocarbons ◽  
Family Members ◽  
Metabolic Activation ◽  
Mouse Epidermis ◽  
Polycyclic Aromatic

Role of alterations in ca2+‐associated signaling pathways in the immunotoxicity of polycyclic aromatic hydrocarbons

1995 ◽  
Vol 45 (2) ◽  
pp. 101-126 ◽  
Author(s):  
Donna R. Davila ◽  
DeAnn P. Davis ◽  
Kerry Campbell ◽  
John C. Cambier ◽  
Letitia A. Zigmond ◽  
...  
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Signaling Pathways ◽  
Aromatic Hydrocarbons ◽  
Polycyclic Aromatic

9,10-Dinaphthylphenanthrene: Synthese, Rotationsisomerie und Photocyclisierung zu polycyclischen aromatischen Kohlenwasserstoffen9,10-Dinaphthylphenanthrenes: Synthesis, Rotational Isomers and Photocyclization to Polycyclic Aromatic Hydrocarbons

1992 ◽  
Vol 47 (12) ◽  
pp. 1764-1774 ◽  
Author(s):  
Karl-Dietrich Gundermann ◽  
Elke Romahn ◽  
Maximilian Zander
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Energy Transfer ◽  
Nmr Spectroscopy ◽  
Aromatic Hydrocarbons ◽  
Trans Isomers ◽  
Preparative Scale ◽  
Rotational Isomers ◽  
Polycyclic Aromatic

9,10-Di(1-naphthyl)phenanthrene (5 a) and 9,10-di(2-naphthyl)phenanthrene (5 b) have been synthesized. It is shown that 5 a and 5b both form two stable rotational (cis/trans) isomers with the naphthalene molecular planes perpendicular to the phenanthrene plane. In the case of 5 a the mixture of the two isomers has been separated in a preparative scale and each isomer characterized by e. g., NMR spectroscopy. Photocyclization of 5a leads to benzo[e]phenanthro[1,2,3,4-ghi]perylene (9) while 5 b yields phenanthro[9,10-i]pentahelicene (14); both hydrocarbons have not been previously described in the literature. The observed selectivities of photocyclization are explained on the basis of the structures and stabilities of the initially formed photoproducts (dihydro structures 15 and 14 a). The role of intramolecular non-radiative singlet-singlet energy transfer (naphthalene → phenanthrene) as competing with photocyclization is discussed in detail.

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