scholarly journals Embelin, a small molecule quinone with a co-clinical power for castrate-resistant prostate cancer

2014 ◽  
Vol 5 ◽  
Author(s):  
Radhika J. Poojari
Keyword(s):  
Prostate Cancer ◽  
Small Molecule ◽  
Castrate Resistant Prostate Cancer ◽  
Castrate Resistant

Phase 1 study of the PSMA-targeted tubulysin small-molecule drug conjugate EC1169 in patients with metastatic castrate-resistant prostate cancer (mCRPC).

2016 ◽  
Vol 34 (15_suppl) ◽  
pp. 2586-2586
Author(s):  
Michael J. Morris ◽  
Daniel Peter Petrylak ◽  
A. Oliver Sartor ◽  
Nicholas J. Vogelzang ◽  
Michael Groaning ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Small Molecule ◽  
Phase 1 ◽  
Phase 1 Study ◽  
Drug Conjugate ◽  
Small Molecule Drug ◽  
Castrate Resistant Prostate Cancer ◽  
Castrate Resistant

scholarly journals Ultrahigh affinity Raman probe for targeted live cell imaging of prostate cancer

2016 ◽  
Vol 7 (11) ◽  
pp. 6779-6785 ◽  
Author(s):  
Ming Li ◽  
Sangeeta Ray Banerjee ◽  
Chao Zheng ◽  
Martin G. Pomper ◽  
Ishan Barman
Keyword(s):  
Prostate Cancer ◽  
Small Molecule ◽  
Live Cell Imaging ◽  
Cell Imaging ◽  
Ultralow Concentrations ◽  
Molecule Inhibitor ◽  
Castrate Resistant Prostate Cancer ◽  
Castrate Resistant ◽  
Raman Probe ◽  
Sers Tags

Leveraging optimally engineered SERS tags and urea-based small-molecule inhibitor of PSMA, we report an ultrahigh binding affinity imaging nanoplex for castrate resistant prostate cancer and demonstrate live single cell vibrational spectroscopic imaging at ultralow concentrations.

Phase 1 study of the PSMA-tubulysin small-molecule drug conjugate EC1169 in pts with metastatic castrate-resistant prostate cancer (mCRPC).

2015 ◽  
Vol 33 (15_suppl) ◽  
pp. e13527-e13527 ◽  
Author(s):  
Samuel Ejadi ◽  
Nicholas J. Vogelzang ◽  
A. Oliver Sartor ◽  
Andrew Habbe ◽  
Binh Nguyen ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Small Molecule ◽  
Phase 1 ◽  
Phase 1 Study ◽  
Drug Conjugate ◽  
Small Molecule Drug ◽  
Castrate Resistant Prostate Cancer ◽  
Castrate Resistant
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