scholarly journals Factors Affecting the Aluminum, Arsenic, Cadmium and Lead Concentrations in the Knee Joint Structures

2021 ◽  
Vol 9 ◽  
Author(s):  
Guoyong Li ◽  
Chunfeng Xiong ◽  
Wenhua Xu ◽  
Runhong Mei ◽  
Tao Cheng ◽  
...  
Keyword(s):  
Knee Joint ◽  
Cancellous Bone ◽  
Toxic Elements ◽  
Cruciate Ligament ◽  
Toxic Element ◽  
Infrapatellar Fat Pad ◽  
Diabetic Patients ◽  
Fat Pad ◽  
Femoral Cartilage ◽  
Anterior Cruciate

Background: Toxic elements, such as aluminum (Al), arsenic (As), cadmium (Cd), and lead (Pb), are persistent environmental pollutants that can cause adverse effects on the health of exposed individuals. Bone is one of the primary target organs of accumulation and potential damage from toxic elements.Objectives: This study was performed to determine the Al, As, Cd, and Pb concentrations in the femoral cancellous bone, femoral cartilage, anterior cruciate ligament, meniscus, tibial cartilage, tibial cancellous bone and infrapatellar fat pad. Furthermore, the aim of this study was to explore the relationships between toxic element concentrations and related factors such as gender, age, place of residence, hypertension and diabetes, and to determine the correlations among these toxic elements in knee joint structures.Methods: The samples used this study were collected from 51 patients following total knee arthroplasty. The Al, As, Cd, and Pb concentrations were determined using inductively coupled plasma optic emission spectrometry.Results: Significant differences were found in the Al, As, Cd, and Pb concentrations among the knee joint structures. Cd concentration in the tibial cancellous bone in women was significantly higher than in men. Pb concentration in the infrapatellar fat pad of urban patients was significantly higher as compared to rural patients. Al concentrations in the femoral cancellous bone, femoral cartilage, anterior cruciate ligament, meniscus and tibial cartilage were significantly higher in patients living in urban areas than in rural areas. As concentration in the tibial cancellous bone of diabetic patients was significantly higher compared to non-diabetic patients. In addition, significant Spearman's positive correlations were found between Al and Pb in the knee joint structures.Conclusion: The obtained results of the investigated toxic elements may serve as a basis for establishing the reference values of Al, As, Cd, and Pb in the knee joint structures. The results reported in the study provides novel data regarding the relationships between the toxic element concentrations and gender, age, place of residence, hypertension and diabetes in the studied structures of knee joint. Furthermore, new interactions among these toxic elements were noted.

scholarly journals Phosphorus Concentration in Knee Joint Structures of Patients Following Replacement Surgery

2019 ◽  
Vol 16 (4) ◽  
pp. 525 ◽  
Author(s):  
Ciosek Żaneta ◽  
Kosik-Bogacka Danuta ◽  
Łanocha-Arendarczyk Natalia ◽  
Kot Karolina ◽  
Karaczun Maciej ◽  
...  
Keyword(s):  
Knee Joint ◽  
Cruciate Ligament ◽  
The Body ◽  
Infrapatellar Fat Pad ◽  
Emission Spectrometry ◽  
Phosphorus Concentration ◽  
Spongy Bone ◽  
Fat Pad ◽  
Hoffa’S Fat Pad ◽  
P Concentration

The aim of the study was to assess phosphorus (P) concentration in structures of the knee joint—including the tibial spongy bone, articular cartilage, meniscus, anterior cruciate ligament, and infrapatellar fat pad (Hoffa’s fat pad)—of patients following knee joint replacement. The study also aimed to assess the influence of selected biological and environmental factors on P concentration in studied parts of the knee joint. Phosphorus concentration was determined using inductively coupled plasma-atomic emission spectrometry (ICP-AES). Statistically significant differences in P concentration were found between different elements of the knee joint. The highest P concentration was measured in the spongy bone (72,746.68 mg kg−1 dw) and the lowest in the Hoffa’s fat pad (1203.19 mg kg−1 dw). P levels were unaffected by gender, age, BMI, place of residence, smoking, or alcohol consumption. Data on P concentration in the osteoarticular elements of the knee may be useful in the interpretation and evaluation of biochemical, morphological, and mechanical changes occurring in the body.

scholarly journals Changes in Infrapatellar Fat Pad Volume From 6 to 12 months Following Anterior Cruciate Ligament Reconstruction and Associations with Patient-Reported Knee Function

2021 ◽  
Author(s):  
Kyle G. Wallace ◽  
Steven J. Pfeiffer ◽  
Laura S. Pietrosimone ◽  
Matthew S. Harkey ◽  
Xiaopeng Zong ◽  
...  
Keyword(s):  
Anterior Cruciate Ligament ◽  
Anterior Cruciate Ligament Reconstruction ◽  
Patient Reported Outcomes ◽  
Ligament Reconstruction ◽  
Cruciate Ligament ◽  
Infrapatellar Fat Pad ◽  
Fat Pad ◽  
Cruciate Ligament Reconstruction ◽  
Patient Reported ◽  
Anterior Cruciate

Context: Hypertrophy of the Infrapatellar Fat Pad (IFP) in idiopathic knee osteoarthritis has been linked to deleterious synovial changes and joint pain related to mechanical tissue impingement; yet, little is known regarding the IFP's volumetric changes following anterior cruciate ligament reconstruction (ACLR). Objective: To examine changes in IFP volume between 6 and 12 months following ACLR and determine associations between patient-reported outcomes and IFP volume at each time point, as well as volume change over time. In a subset of individuals, we examined inter-limb IFP volume differences 12 months post-ACLR. Study Design: Prospective cohort study Setting: Laboratory Patients or Other Participants: We included 26 participants (13 females, 13 males, 21.88±3.58 years, 23.82±2.21 kg/m2) for our primary aims and 13 of those participants (8 females, 5 males, 21.15±3.85 years, 23.01±2.01 kg/m2) for our exploratory aim. Main Outcome Measure(s): Using magnetic resonance imaging, we evaluated IFP volume change between 6 and 12 months post-ACLR in the ACLR limb and between-limb differences at 12 months in a subset of participants. International Knee Documentation Committee subjective knee evaluation (IKDC) scores were collected at 6-month and 12-month follow-ups and associations between IFP volume and patient-reported outcomes were determined. Results: IFP volume in the ACLR limb significantly increased from 6 (19.67±6.30 cm3) to 12 (21.26±6.91 cm3) months post-ACLR. Greater increases of IFP volume between 6 and 12 months significantly associated with better 6-month IKDC scores (r=0.44, P=0.03). IFP volume was significantly greater in the uninjured limb (22.71±7.87 cm3) compared to the ACLR limb (20.75±9.03 cm3) 12 months post-ACLR. Conclusions: IFP volume increased between 6 and 12 months post-ACLR; however, the IFP volume of the ACLR limb remained smaller than the uninjured limb at 12-months. Additionally, those with better knee function 6 months post-ACLR demonstrated greater increases in IFP volume between 6 and 12 months post-ACLR. This suggests greater IFP volumes may play a role in long-term joint health following ACLR.

scholarly journals Flexibility of infrapatellar fat pad affecting anterior knee pain 6 months after anterior cruciate ligament reconstruction with hamstring autograft

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Takashi Kitagawa ◽  
Junsuke Nakase ◽  
Yasushi Takata ◽  
Kengo Shimozaki ◽  
Kazuki Asai ◽  
...  
Keyword(s):  
Blood Flow ◽  
Ligament Reconstruction ◽  
Cruciate Ligament ◽  
Infrapatellar Fat Pad ◽  
Fat Pad ◽  
Thickness Change ◽  
Cruciate Ligament Reconstruction ◽  
Anterior Cruciate ◽  
Anterior Knee ◽  
Increased Blood Flow

AbstractThis study aimed to identify factors affecting anterior knee pain (AKP) after anterior cruciate ligament reconstruction (ACLR) with hamstring tendon autograft using ultrasonography. Forty-two patients were evaluated by ultrasound, 6 months after ACLR. The thickness of the superficial part of the infrapatellar fat pad was measured, as well as the thickness change ratio between the two angles. Color Doppler evaluated the rate of blood flow in the fat pad. AKP was assessed with the Kujala Scale. The correlations between AKP and age, body mass index, the thickness change ratio, and the grade of increased blood flow were examined. Independent variables showing significant correlations with AKP were used for multiple linear regression analysis. There were significant correlations between AKP and age (r = − 0.68), body mass index (r = − 0.37), the thickness change ratio of the fat pad (r = 0.73) and the grade of increased blood flow (r = − 0.42), respectively. Age and the thickness change ratio of the fat pad affected the AKP score (R2 = 0.56). After ACLR, older age and a decrease in the thickness change ratio of the superficial area of the infrapatellar fat pad appear to affect post-operative AKP after 6 months.

scholarly journals Anterior cruciate ligament transection alters the n-3/n-6 fatty acid balance in the lapine infrapatellar fat pad

2019 ◽  
Vol 18 (1) ◽  
Author(s):  
Anne-Mari Mustonen ◽  
Reijo Käkelä ◽  
Mikko A. J. Finnilä ◽  
Andrew Sawatsky ◽  
Rami K. Korhonen ◽  
...  
Keyword(s):  
Anterior Cruciate Ligament ◽  
Fatty Acid ◽  
Cruciate Ligament ◽  
Infrapatellar Fat Pad ◽  
Fat Pad ◽  
Anterior Cruciate Ligament Transection ◽  
Anterior Cruciate

Immunohistologic Analysis of Synovium in Infrapatellar Fat Pad After Anterior Cruciate Ligament Injury

1995 ◽  
Vol 23 (6) ◽  
pp. 763-768 ◽  
Author(s):  
Shunichi Murakami ◽  
Takeshi Muneta ◽  
Kohtaro Furuya ◽  
Ichiro Saito ◽  
Nobuyuki Miyasaka ◽  
...  
Keyword(s):  
Anterior Cruciate Ligament ◽  
Anterior Cruciate Ligament Injury ◽  
Cruciate Ligament ◽  
Infrapatellar Fat Pad ◽  
Ligament Injury ◽  
Fat Pad ◽  
Anterior Cruciate
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