scholarly journals Recovery after General Anaesthesia in Adult Horses: A Structured Summary of the Literature

Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1777
Author(s):  
Miguel Gozalo-Marcilla ◽  
Simone Katja Ringer
Keyword(s):  
Literature Review ◽  
General Anaesthesia ◽  
Respiratory System ◽  
Web Of Science ◽  
Case Series ◽  
Outcome Studies ◽  
Total Intravenous Anaesthesia ◽  
Intravenous Anaesthesia ◽  
Expert Opinions ◽  
Structured Literature Review

Recovery remains the most dangerous phase of general anaesthesia in horses. The objective of this publication was to perform a structured literature review including levels of evidence (LoE) of each study with the keywords “recovery anaesthesia horse”, entered at once, in the search browsers PubMed and Web of Science. The two authors independently evaluated each candidate article. A final list with 444 articles was obtained on 5 April 2021, classified as: 41 “narrative reviews/expert opinions”, 16 “retrospective outcome studies”, 5 “surveys”, 59 “premedication/sedation and induction drugs”, 27 “maintenance with inhalant agents”, 55 “maintenance with total intravenous anaesthesia (TIVA)”, 3 “TIVA versus inhalants”, 56 “maintenance with partial intravenous anaesthesia (PIVA)”, 27 “other drugs used during maintenance”, 18 “drugs before/during recovery”, 18 “recovery systems”, 21 “respiratory system in recovery”, 41 “other factors”, 51 “case series/reports” and 6 “systems to score recoveries”. Of them, 167 were LoE 1, 36 LoE 2, 33 LoE 3, 110 LoE 4, 90 LoE 5 and 8 could not be classified based on the available abstract. This review can be used as an up-to-date compilation of the literature about recovery after general anaesthesia in adult horses that tried to minimise the bias inherent to narrative reviews.

scholarly journals Intravenous anaesthesia in goats: A review

2013 ◽  
Vol 84 (1) ◽  
Author(s):  
T. Brighton Dzikiti
Keyword(s):  
General Anaesthesia ◽  
Muscle Relaxation ◽  
Scientific Information ◽  
Working Environment ◽  
Total Intravenous Anaesthesia ◽  
Intravenous Anaesthesia ◽  
Anaesthetic Agents ◽  
Inhalation Anaesthetic ◽  
Intravenous Anaesthetic ◽  
Balanced Anaesthesia

Intravenous anaesthesia is gradually becoming popular in veterinary practice. Traditionally, general anaesthesia is induced with intravenous drugs and then maintained with inhalation agents. Inhalation anaesthetic agents cause more significant dose-dependent cardiorespiratory depression than intravenous anaesthetic drugs, creating a need to use less of the inhalation anaesthetic agents for maintenance of general anaesthesia by supplementing with intravenous anaesthesia drugs. Better still, if anaesthesia is maintained completely with intravenous anaesthetic drugs, autonomic functions remain more stable intra-operatively. Patient recovery from anaesthesia is smoother and there is less pollution of the working environment than happens with inhalation anaesthetic agents. Recently, a number of drugs with profiles (pharmacokinetic and pharmacodynamic) suitable for prolonged intravenous anaesthesia have been studied, mostly in humans and, to a certain extent, in dogs and horses. There is currently very little scientific information on total intravenous anaesthesia in goats, although, in the past few years, some scholarly scientific articles on drugs suitable for partial intravenous anaesthesia in goats have been published. This review article explored the information available on drugs that have been assessed for partial intravenous anaesthesia in goats, with the aim of promoting incorporation of these drugs into total intravenous anaesthesia protocols in clinical practice. That way, balanced anaesthesia, a technique in which drugs are included in anaesthetic protocols for specific desired effects (hypnosis, analgesia, muscle relaxation, autonomic stabilisation) may be utilised in improving the welfare of goats undergoing general anaesthesia.

scholarly journals General Anaesthesia for Renal Transplantation in Latvia: A Critical Analysis Based on Clinical Experience

2013 ◽  
Vol 67 (1) ◽  
pp. 28-34 ◽  
Author(s):  
Antoņina Sondore ◽  
Sanita Ūdre ◽  
Jānis Nemme ◽  
Laimdota Grašiņa ◽  
Ieva Kruževņaka ◽  
...  
Keyword(s):  
Renal Transplantation ◽  
General Anaesthesia ◽  
Venous Pressure ◽  
Stage I ◽  
Stage Ii ◽  
Stage Iii ◽  
Haemodynamic Instability ◽  
Total Intravenous Anaesthesia ◽  
Intravenous Anaesthesia ◽  
Arterial Blood

Anaesthesia methods for surgical procedures, as well as for organ transplantation, have experienced remarkable changes over the past 40 years. Cadaveric renal transplant function may be impaired by haemodynamic instability induced by anaesthesia drugs. This study aimed to analyse the safety and effectiveness of the different anaesthesia methods used for renal transplantation in Latvia since 1973, with focus on its haemodynamic effects. In this retrospective study anaesthesia chart review was conducted for 607 patients (pts), aged 17-75 yrs, ASA III/IV, undergoing renal transplantation using general anaesthesia in the following periods: 1973-1990 (stage I - 282 pts); 1991-2000 (stage II - 145 pts); 2001-2011 (stage III - 180 pts). Haemodynamic data (systolic, diastolic, mean arterial blood pressure and central venous pressure) were measured prior to premedication and induction of anaesthesia, immediately afterwards, during the surgery and up to its completion with the special attention regarding the time of graft reperfusion. The main perioperative problems of the anaesthesia methods used during stage I (barbiturates, viadril, neuroleptanalgesics, sodium oxybutyrate, halothane, nitrous oxide) was haemodynamic instability in 60% of cases and apnea due to central depression and long-time peripheral neuromuscular blockade. Two patients died due to underlying comorbid conditions, including hyperhidration and oedema pulmonum. Substantial haemodynamic changes during total intravenous anaesthesia with propofol and combined anaesthesia propofol-isoflurane (stage II) were not observed. At the time of graft reperfusion, the incidence of hypotension was slightly higher in patients anaesthetised with isoflurane than in those who received sevoflurane (stage III), but this difference was not significant (P > 0.05). Kidney functioned immediately in 75% of cases and delayed function was observed in 25% of cases in sevoflurane and isoflurane groups. The modern anaesthetic agents provide a great margin of safety during renal transplantation. Total intravenous anaesthesia with midasolam-fentanyl-propofol and general anaesthesia with propofol-isoflurane, propofol-sevoflurane can be safely used. During renal transplantation, anaesthesiologists must optimise volume status, perfusion pressure and promote survival of the renal graft.

scholarly journals Comparison of Balanced General and Total Intravenous Anaesthesia for Gasser Ganglion Percutaneous Balloon Microcompression for Trigeminal Neuralgia

2021 ◽  
pp. 1-3
Author(s):  
Patricia Heise ◽  
◽  
Marcos Baabor ◽  
Claudia Marin ◽  
◽  
...  
Keyword(s):  
Blood Pressure ◽  
Trigeminal Neuralgia ◽  
General Anaesthesia ◽  
Total Intravenous Anaesthesia ◽  
Intravenous Anesthesia ◽  
Intravenous Anaesthesia ◽  
Percutaneous Balloon ◽  
Group A ◽  
Group B ◽  
To Receive

Objective: To compare the effectiveness between balanced general anaesthesia and total intravenous anaesthesia for the hemodynamic control of patients undergoing percutaneous balloon microcompression of the Gasser’s ganglion in trigeminal neuralgia. Patients and methods: A retrospective trial was conducted in thirty patients with the diagnosis of essential trigeminal neuralgia, aged 37 to 82 years old, ASA I and II. The participants were randomly allocated in two groups: Group A, to receive balanced general anaesthesia (BGA) with isoflurane/fentanyl, or Group B, to receive total intravenous anesthesia (TIVA) with propofol/remifentanil. The systolic, diastolic and mean arterial blood pressure, heart rate and oximetry were measured at basal state, entrance to Meckel’s cavum and during the balloon compression. Statistical analysis with the Student T test for continuous quantitative variables and x2 (Chi square) for qualitative variables was performed. Results: The systolic blood pressure was significantly higher in group A at the moment of greatest stimulation. The technique propofol/remifentanil (group B) obtained better hemodynamic control and its management was easier. The incidence of bradycardia was similar in both groups and kept inverse relation with use of previous atropine. Conclusions: Total intravenous anesthesia (TIVA) is an attractive alternative to balanced general anesthesia due to the better hemodynamic response and the quick recovery that this technique offers. Moreover, Atropine use before the procedure is a measure that could benefit patients

Análisis de contenido y nivel de evidencia de los artículos sobre Covid-19 más citados en la Web of Science

2021 ◽  
Author(s):  
José-Antonio Salvador-Oliván ◽  
Gonzalo Marco-Cuenca ◽  
Rosario Arquero-Avilés
Keyword(s):  
Peer Review ◽  
Review Process ◽  
Web Of Science ◽  
Peer Review Process ◽  
Case Series ◽  
Controlled Clinical Trial ◽  
Scientific Quality ◽  
Level Of Evidence ◽  
Expert Opinions ◽  
Bibliographic Data

The scientific literature on Covid-10 has seen unprecedented growth, becoming published so rapidly that it has caused a loss of quality and the peer review process to be questioned. This research analyzes the characteristics of the publications with a wider impact on Covid-19, mainly those related to the content, the quality and level of evidence of the studies. Web of Science Core Collection was searched for articles containing the terms Covid-19 and SARS-CoV-19 and the 100 most cited articles published in 2020 were selected. The data extracted included bibliographic data, dates of submission, acceptance and publication in the journals, main topics covered, type of study and level of evidence according to the SIGN scale, and the presence of corrections. Half of the articles were published in 3 journals, most of them in the first months of 2020. The most frequent types of studies corresponded to case series, narrative reviews and expert opinions, with only 1 randomized controlled clinical trial. The articles focused mainly on the clinical characteristics and complications of the patients, diagnostic and treatment methods, as well as the epidemiology and characteristics of the virus. The design of these studies reflects a low level of evidence, and data and scientific quality may be affected by how quickly they are published, and the peer review process is performed. Resumen El crecimiento sin precedentes de la bibliografía científica sobre Covid-19 y la rapidez en su publicación ha llevado a cuestionar la calidad y el proceso de revisión por pares. Este estudio tiene como objetivo analizar las características de las publicaciones con mayor impacto sobre Covid-19, principalmente las relacionadas con el contenido, la calidad y nivel de evidencia de los estudios. Para ello, se buscó en la colección principal de Web of Science los artículos que contenían los términos Covid-19 y SARS-CoV-19 en el campo del título y se seleccionaron los 100 artículos más citados publicados en el año 2020. Además de los datos bibliográficos, se recogieron datos de las fechas de envío, aceptación y publicación en las revistas, principales temas tratados, tipo de estudio y nivel de evidencia según la escala SIGN, así como de la presencia de correcciones. Más de la mitad de los artículos están publicados en 3 revistas, y la mayoría de ellos en los primeros meses de 2020. Los tipos de estudios más frecuentes son series de casos, revisiones narrativas y opiniones de expertos, con solo 1 ensayo clínico controlado aleatorizado. El contenido de los artículos trata principalmente de las características clínicas y complicaciones de los enfermos, métodos diagnósticos y de tratamiento, así como de la epidemiología y características del virus. Los artículos presentan un nivel de evidencia bajo, a pesar de estar publicados en revistas de medicina con muy alto factor de impacto. El tiempo transcurrido entre la fecha de envío y de publicación es muy corto y cuestiona la realización y/o rigor del proceso de revisión por pares.

scholarly journals A retrospective case series of computer-controlled total intravenous anaesthesia in dogs presented for neurosurgery

2004 ◽  
Vol 75 (2) ◽  
Author(s):  
K.E. Joubert ◽  
N. Keller ◽  
C.J. Du Plessis
Keyword(s):  
Case Series ◽  
Anaesthetic Management ◽  
Total Intravenous Anaesthesia ◽  
Retrospective Case ◽  
Intravenous Anaesthesia ◽  
Tumour Metastasis ◽  
Haemodynamic Stability ◽  
Syringe Driver ◽  
End Tidal ◽  
Balanced Anaesthesia

This article describes the anaesthetic management and use of total intravenous anaesthesia (TIVA) for neurosurgery in 4 dogs. Propofol in conjunction with morphine was used for the maintenance of anaesthesia. Anaesthesia was induced with either thiopentone or propofol. The program Stelpump (a target-controlled infusion program) was run on a laptop and connected to a syringe driver via an RS 232 cable. The program was found to be reliable and safe for the administration of TIVA in dogs. Invasive monitoring was required in order to monitor cardiovascular changes during surgery. Ventilation was controlled to maintain the end-tidal carbon dioxide below 40 mm Hg. The anaesthesia was characterised by haemodynamic stability. The haemodynamic stability was probably the result of the choice of TIVA and balanced anaesthesia. Intracranial pressure and oedema was controlled with dexamethasone, mannitol and ventilatory management either in combination or alone. Three dogs survived to hospital discharge and 1 dog was euthanased 2 weeks later due to tumour metastasis. The development and characterisation of the anaesthetic effects of TIVA needs to be elucidated in order to provide clinicians with rational guidelines for the appropriate use of TIVA in veterinary medicine.

General Anaesthesia for Cleft Lip and Palate Surgery Team Activities in Cambodia

1997 ◽  
Vol 27 (3) ◽  
pp. 153-155 ◽  
Author(s):  
Yumiko Ishizawa ◽  
Yujiro Handa ◽  
Katsuyuki Tanaka ◽  
Kazumi Taki
Keyword(s):  
Developing Countries ◽  
Surgical Treatment ◽  
General Anaesthesia ◽  
Postoperative Period ◽  
Cleft Lip ◽  
Low Dose ◽  
Cleft Lip And Palate ◽  
Total Intravenous Anaesthesia ◽  
Intravenous Anaesthesia ◽  
Governmental Organization

Cleft lip and palate surgery team activities in Cambodia were launched in 1989 by a Japanese non-governmental organization. The objectives of the project were to provide appropriate surgical treatment and safe general anaesthesia for local patients, and also to teach general anaesthesia and surgery to local medical staff. A surgery team was sent on four occasions between 1991 and 1993 and a total of 130 patients received surgical treatment and general anaesthesia. Anaesthesia techniques employed included total intravenous anaesthesia in 70 patients and intravenous anaesthesia and low dose halothane in 60 patients. There were no major complications, such as airway obstruction or apnoea in the postoperative period. Total intravenous anaesthesia is an appropriate technique for patients in developing countries. The teaching of anaesthesia should be emphasized during the surgery team activities.

scholarly journals If the Price is Right? Cost Analysis of Propofol Infusions and Sevoflurane Anaesthesia in Endoscopic Cases

2021 ◽  
Vol 15 (1) ◽  
pp. 20-21
Author(s):  
Lachlan J. Gan ◽  
Gavin Sullivan
Keyword(s):  
Laryngeal Mask Airway ◽  
Cost Analysis ◽  
General Anaesthesia ◽  
Current Data ◽  
Laryngeal Mask ◽  
Total Intravenous Anaesthesia ◽  
Intravenous Anaesthesia ◽  
Sevoflurane Anaesthesia ◽  
The Cost

The environmental superiority of Total Intravenous Anaesthesia (TIVA) compared to inhaled agents has been recognised by ANZCA in a 2019 statement. Yet what about cost? Little current data has been published on this topic. We conducted a cost analysis and audit of propofol use in 71 endoscopy cases (colonoscopy/gastroscopy), taking into account the cost of adjuncts (syringes, tubing, and discarded propofol). We then compared these to calculated costs of the same cases performed with sevoflurane anaesthesia. In terms of the agent, propofol was 35% cheaper, costing $1.60 for an average endoscopy compared to a sevoflurane cost of $2.46. Including the cost of adjuncts (including a laryngeal mask airway for sevoflurane anaesthesia), endoscopy cases with propofol infusions were 80% cheaper than the same case performed under sevoflurane general anaesthesia ($3.08 vs $15.48). Although pricing may vary from hospital to hospital, our data suggests choosing propofol costs less in endoscopy.

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