scholarly journals Role of Akt Isoforms Controlling Cancer Stem Cell Survival, Phenotype and Self-Renewal

Biomedicines ◽  
2018 ◽  
Vol 6 (1) ◽  
pp. 29 ◽  
Author(s):  
Sergio Rivas ◽  
Carla Gómez-Oro ◽  
Inés Antón ◽  
Francisco Wandosell
2010 ◽  
Author(s):  
Min Zhang ◽  
Dale Hogan ◽  
Aramati Bindu Reddy ◽  
Kota Ramana ◽  
Satish Srivastava ◽  
...  

2019 ◽  
Vol 12 ◽  
pp. 117906601983696 ◽  
Author(s):  
Elle Koren ◽  
Yaron Fuchs

Although much is known regarding intestinal stem cell (ISC) self-renewal and differentiation, the specific mechanisms used for their elimination is unclear. We recently discovered that the pro-apoptotic protein ARTS, a Septin4 isoform, interacts with X-linked inhibitor of apoptosis (XIAP) in the ISC niche to regulate stem cell survival during intestinal homeostasis and regeneration. These findings point to an intriguing avenue of translational research, examining how manipulation of stem cell apoptosis through the ARTS/XIAP module can affect stem-cell-dependent processes.


2017 ◽  
Vol 32 (7) ◽  
pp. 906-919 ◽  
Author(s):  
Dhanak Gupta ◽  
David M Grant ◽  
Kazi M Zakir Hossain ◽  
Ifty Ahmed ◽  
Virginie Sottile

2016 ◽  
Vol 4 (4) ◽  
pp. 1 ◽  
Author(s):  
Hussam S Eltoukhy ◽  
Garima Sinha ◽  
Caitlyn Moore ◽  
Khadidiatou Guiro ◽  
Pranela Rameshwar

Author(s):  
Umayal Sivagnanalingam ◽  
John Attanasio ◽  
Thomas Mariani ◽  
Patricia J. Sime ◽  
Jody Gascon ◽  
...  

2016 ◽  
Vol 76 (24) ◽  
pp. 7265-7276 ◽  
Author(s):  
Matthew L. Fisher ◽  
Candace Kerr ◽  
Gautam Adhikary ◽  
Dan Grun ◽  
Wen Xu ◽  
...  

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