scholarly journals Convolutional Neural Network and Bidirectional Long Short-Term Memory-Based Method for Predicting Drug–Disease Associations

Cells ◽  
2019 ◽  
Vol 8 (7) ◽  
pp. 705 ◽  
Author(s):  
Xuan ◽  
Ye ◽  
Zhang ◽  
Zhao ◽  
Sun
Keyword(s):  
Neural Network ◽  
Convolutional Neural Network ◽  
Short Term Memory ◽  
Potential Drug ◽  
Short Term ◽  
Term Memory ◽  
Path Representation ◽  
Disease Pair ◽  
Disease Associations ◽  
Long Short Term Memory

Identifying novel indications for approved drugs can accelerate drug development and reduce research costs. Most previous studies used shallow models for prioritizing the potential drug-related diseases and failed to deeply integrate the paths between drugs and diseases which may contain additional association information. A deep-learning-based method for predicting drug–disease associations by integrating useful information is needed. We proposed a novel method based on a convolutional neural network (CNN) and bidirectional long short-term memory (BiLSTM)—CBPred—for predicting drug-related diseases. Our method deeply integrates similarities and associations between drugs and diseases, and paths among drug-disease pairs. The CNN-based framework focuses on learning the original representation of a drug-disease pair from their similarities and associations. As the drug-disease association possibility also depends on the multiple paths between them, the BiLSTM-based framework mainly learns the path representation of the drug-disease pair. In addition, considering that different paths have discriminate contributions to the association prediction, an attention mechanism at path level is constructed. Our method, CBPred, showed better performance and retrieved more real associations in the front of the results, which is more important for biologists. Case studies further confirmed that CBPred can discover potential drug-disease associations.

scholarly journals Multiple Pedestrians and Vehicles Tracking in Aerial Imagery Using a Convolutional Neural Network

2021 ◽  
Vol 13 (10) ◽  
pp. 1953
Author(s):  
Seyed Majid Azimi ◽  
Maximilian Kraus ◽  
Reza Bahmanyar ◽  
Peter Reinartz
Keyword(s):  
Neural Network ◽  
Deep Learning ◽  
Convolutional Neural Network ◽  
Object Tracking ◽  
Short Term Memory ◽  
Aerial Imagery ◽  
Future Research ◽  
Short Term ◽  
Term Memory ◽  
Long Short Term Memory

In this paper, we address various challenges in multi-pedestrian and vehicle tracking in high-resolution aerial imagery by intensive evaluation of a number of traditional and Deep Learning based Single- and Multi-Object Tracking methods. We also describe our proposed Deep Learning based Multi-Object Tracking method AerialMPTNet that fuses appearance, temporal, and graphical information using a Siamese Neural Network, a Long Short-Term Memory, and a Graph Convolutional Neural Network module for more accurate and stable tracking. Moreover, we investigate the influence of the Squeeze-and-Excitation layers and Online Hard Example Mining on the performance of AerialMPTNet. To the best of our knowledge, we are the first to use these two for regression-based Multi-Object Tracking. Additionally, we studied and compared the L1 and Huber loss functions. In our experiments, we extensively evaluate AerialMPTNet on three aerial Multi-Object Tracking datasets, namely AerialMPT and KIT AIS pedestrian and vehicle datasets. Qualitative and quantitative results show that AerialMPTNet outperforms all previous methods for the pedestrian datasets and achieves competitive results for the vehicle dataset. In addition, Long Short-Term Memory and Graph Convolutional Neural Network modules enhance the tracking performance. Moreover, using Squeeze-and-Excitation and Online Hard Example Mining significantly helps for some cases while degrades the results for other cases. In addition, according to the results, L1 yields better results with respect to Huber loss for most of the scenarios. The presented results provide a deep insight into challenges and opportunities of the aerial Multi-Object Tracking domain, paving the way for future research.

scholarly journals Pemanfaatan Asynchronous Advantage Actor-Critic Dalam Pembuatan AI Game Bot Pada Game Arcade

2019 ◽  
Vol 1 (2) ◽  
pp. 74-84
Author(s):  
Evan Kusuma Susanto ◽  
Yosi Kristian
Keyword(s):  
Neural Network ◽  
Artificial Intelligence ◽  
Reinforcement Learning ◽  
Convolutional Neural Network ◽  
Short Term Memory ◽  
Trial And Error ◽  
Short Term ◽  
Term Memory ◽  
Memory Network ◽  
Long Short Term Memory

Asynchronous Advantage Actor-Critic (A3C) adalah sebuah algoritma deep reinforcement learning yang dikembangkan oleh Google DeepMind. Algoritma ini dapat digunakan untuk menciptakan sebuah arsitektur artificial intelligence yang dapat menguasai berbagai jenis game yang berbeda melalui trial and error dengan mempelajari tempilan layar game dan skor yang diperoleh dari hasil tindakannya tanpa campur tangan manusia. Sebuah network A3C terdiri dari Convolutional Neural Network (CNN) di bagian depan, Long Short-Term Memory Network (LSTM) di tengah, dan sebuah Actor-Critic network di bagian belakang. CNN berguna sebagai perangkum dari citra output layar dengan mengekstrak fitur-fitur yang penting yang terdapat pada layar. LSTM berguna sebagai pengingat keadaan game sebelumnya. Actor-Critic Network berguna untuk menentukan tindakan terbaik untuk dilakukan ketika dihadapkan dengan suatu kondisi tertentu. Dari hasil percobaan yang dilakukan, metode ini cukup efektif dan dapat mengalahkan pemain pemula dalam memainkan 5 game yang digunakan sebagai bahan uji coba.

scholarly journals A hybrid of convolutional neural network and long short-term memory network approach to predictive maintenance

2022 ◽  
Vol 12 (1) ◽  
pp. 721
Author(s):  
Ahmed Nasser ◽  
Huthaifa AL-Khazraji
Keyword(s):  
Neural Network ◽  
Convolutional Neural Network ◽  
Short Term Memory ◽  
Predictive Maintenance ◽  
Fault Prediction ◽  
Gradient Boosting ◽  
Short Term ◽  
Term Memory ◽  
Memory Network ◽  
Long Short Term Memory

<p>Predictive maintenance (PdM) is a successful strategy used to reduce cost by minimizing the breakdown stoppages and production loss. The massive amount of data that results from the integration between the physical and digital systems of the production process makes it possible for deep learning (DL) algorithms to be applied and utilized for fault prediction and diagnosis. This paper presents a hybrid convolutional neural network based and long short-term memory network (CNN-LSTM) approach to a predictive maintenance problem. The proposed CNN-LSTM approach enhances the predictive accuracy and also reduces the complexity of the model. To evaluate the proposed model, two comparisons with regular LSTM and gradient boosting decision tree (GBDT) methods using a freely available dataset have been made. The PdM model based on CNN-LSTM method demonstrates better prediction accuracy compared to the regular LSTM, where the average F-Score increases form 93.34% in the case of regular LSTM to 97.48% for the proposed CNN-LSTM. Compared to the related works the proposed hybrid CNN-LSTM PdM approach achieved better results in term of accuracy.</p>

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