scholarly journals Tracheal Stenosis and Congenital Heart Disease in Trisomy 21

Children ◽  
2019 ◽  
Vol 6 (9) ◽  
pp. 98
Author(s):  
Kylat
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Tracheal Stenosis ◽  
Trisomy 21 ◽  
Congenital Heart ◽  
Upper Airway ◽  
Chromosomal Anomalies ◽  
Rare Association ◽  
Wide Range ◽  
Airway Anomalies

Tracheal rings (TR) are rare, congenital cartilaginous defect of the upper airway and are usually due to complete or near complete circumferential cartilaginous tracheal rings, with variable degrees of tracheal stenosis (TS) and shortening. Chromosomal anomalies like trisomy 21 are characteristically associated with a wide range of upper airway anomalies including TS and congenital heart disease (CHD). However, the overall prevalence of severe forms of TS is rare and reported in 1.2% of all CHD patients. Herein, we present a rare association of severe TS due to complete tracheal rings in a trisomy 21 patient with CHD and the challenges in the management.

scholarly journals Trisomy 21 and Ebstein Anomaly: Diagnosis and Prognosis of a Rare Association

2020 ◽  
Author(s):  
Gabriela Rangel Brandão ◽  
Amanda Thum Welter ◽  
Gabriel Dotta Abech ◽  
Carla Bastos da Costa Almeida ◽  
Caio Seiti Mestre Okabayashi ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Literature Review ◽  
Tricuspid Valve ◽  
Trisomy 21 ◽  
Congenital Heart ◽  
Good Prognosis ◽  
Ebstein Anomaly ◽  
Rare Association ◽  
Diagnosis And Prognosis

AbstractTrisomy 21 is considered the most common chromosomal aneuploidy, and congenital heart disease (CHD) is highly prevalent and relevant to the morbidity and mortality of these patients. Ebstein anomaly (EA) is a rare CHD characterized by tricuspid valve dysplasia with inferior septal leaflet displacement. Herein, we describe a patient with trisomy 21 who presented with EA and discuss the association between the two conditions based on a literature review. We conclude that the concomitant occurrence of both conditions is considered to be rare. These individuals are most frequently diagnosed during birth and childhood, and they usually have a good prognosis, as observed with our patient and is typical for EA patients in general. However, it is important to be aware that electrophysiologic anomalies may also be present.

scholarly journals RARE ASSOCIATION OF CELIAC DISEASE WITH CONGENITAL HEART DISEASE

2019 ◽  
Vol 6 (5) ◽  
pp. 255-256
Author(s):  
Rashi Bhargava ◽  
Aaradhana Singh ◽  
Anju Aggarwal ◽  
Manish Narang
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Celiac Disease ◽  
Congenital Heart ◽  
Rare Association

scholarly journals Environmental Risk Factors and Congenital Heart Disease: An Umbrella Review of 165 Systematic Reviews and Meta-Analyses With More Than 120 Million Participants

2021 ◽  
Vol 8 ◽  
Author(s):  
Tie-Ning Zhang ◽  
Qi-Jun Wu ◽  
Ya-Shu Liu ◽  
Jia-Le Lv ◽  
Hui Sun ◽  
...  
Keyword(s):  
Risk Factors ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Environmental Factors ◽  
Congenital Heart ◽  
Prediction Intervals ◽  
Umbrella Review ◽  
Wide Range ◽  
Null Value ◽  
Meta Analyses

Background: The etiology of congenital heart disease (CHD) has been extensively studied in the past decades. Therefore, it is critical to clarify clear hierarchies of evidence between types of environmental factors and CHD.Methods: Electronic searches in PubMed, Embase, Web of Science, Cochrane database were conducted from inception to April 20, 2020 for meta-analyses investigating the aforementioned topic.Results: Overall, 41 studies including a total of 165 meta-analyses of different environmental factors and CHD were examined, covering a wide range of risk factors. The summary random effects estimates were significant at P < 0.05 in 63 meta-analyses (38%), and 15 associations (9%) were significant at P < 10−6. Of these meta-analyses, eventually one risk factor (severe obesity; relative risk: 1.38, 95% confidence interval: 1.30–1.47) had significant summary associations at P < 10−6, included more than 1,000 cases, had 95% prediction intervals excluding the null value, and were not suggestive of large heterogeneity (I2 < 50%), small-study effects (P-value for Egger's test > 0.10), or excess significance (P > 0.10). Eight associations (5%) (including maternal lithium exposure, maternal obesity, maternal alcohol consumption, and maternal fever) had results that were significant at P < 10−6, included more than 1,000 cases, and had 95% prediction intervals excluding the null value (highly suggestive).Conclusion: This umbrella review shows that many environmental factors have substantial evidence in relation to the risk of developing CHD. More and better-designed studies are needed to establish robust evidence between environmental factors and CHD.Systematic Review Registration: [PROSPERO], identifier [CRD42020193381].

scholarly journals Detection of Tracheal Stenosis by Cineangiocardiography in Infants with Congenital Heart Disease

1997 ◽  
Vol 85 (5) ◽  
pp. 1180-1181 ◽  
Author(s):  
Naoki Yahagi ◽  
Keiji Kumon ◽  
Yasuhiko Watanabe ◽  
Hironobu Tanigami ◽  
Masaki Haruna ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Tracheal Stenosis ◽  
Congenital Heart

scholarly journals Fatal Combination of Severe Tracheal Stenosis with Congenital Heart Disease

2001 ◽  
Vol 8 (2) ◽  
pp. 91-94
Author(s):  
György Baktai ◽  
Edgár Székely ◽  
György Simon ◽  
Márta Fáczán ◽  
Károly Balázs ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Tracheal Stenosis ◽  
Congenital Heart

Congenital heart disease in trisomy 21 mosaicism

1993 ◽  
Vol 122 (3) ◽  
pp. 500-501 ◽  
Author(s):  
Bruno Marino ◽  
Andrea de Zorzi
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Trisomy 21 ◽  
Congenital Heart
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