scholarly journals Machine Learning Methods for Histopathological Image Analysis: A Review

Electronics ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 562
Author(s):  
Jonathan de Matos ◽  
Steve Ataky ◽  
Alceu de Souza Britto ◽  
Luiz Soares de Oliveira ◽  
Alessandro Lameiras Koerich

Histopathological images (HIs) are the gold standard for evaluating some types of tumors for cancer diagnosis. The analysis of such images is time and resource-consuming and very challenging even for experienced pathologists, resulting in inter-observer and intra-observer disagreements. One of the ways of accelerating such an analysis is to use computer-aided diagnosis (CAD) systems. This paper presents a review on machine learning methods for histopathological image analysis, including shallow and deep learning methods. We also cover the most common tasks in HI analysis, such as segmentation and feature extraction. Besides, we present a list of publicly available and private datasets that have been used in HI research.

2020 ◽  
Vol 13 (1) ◽  
pp. 106-118
Author(s):  
Santisudha Panigrahi ◽  
Tripti Swarnkar

Oral diseases are the 6th most revealed malignancy happening in head and neck regions found mainly in south Asian countries. It is the most common cancer with fourteen deaths in an hour on a yearly basis, as per the WHO oral cancer incidence in India. Due to the cost of tests, mistakes in the recognition procedure, and the enormous remaining task at hand of the cytopathologist, oral growths cannot be diagnosed promptly. This area is open to be looked into by biomedical analysts to identify it at an early stage. At present, with the advent of entire slide computerized scanners and tissue histopathology, there is a gigantic aggregation of advanced digital histopathological images, which has prompted the necessity for their analysis. A lot of computer aided analysis techniques have been developed by utilizing machine learning strategies for prediction and prognosis of cancer. In this review paper, first various steps of obtaining histopathological images, followed by the visualization and classification done by the doctors are discussed. As machine learning techniques are well known, in the second part of this review, the works done for histopathological image analysis as well as other oral datasets using these strategies for growth prognosis and anticipation are discussed. Comparing the pitfalls of machine learning and how it has overcome by deep learning mostly for image recognition tasks are also discussed subsequently. The third part of the manuscript describes how deep learning is beneficial and widely used in different cancer domains. Due to the remarkable growth of deep learning and wide applicability, it is best suited for the prognosis of oral disease. The aim of this review is to provide insight to the researchers opting to work for oral cancer by implementing deep learning and artificial neural networks.


2017 ◽  
Author(s):  
Βασίλειος Κανάς

Η δουλειά η οποία παρουσιάζεται σε αυτήν την διδακτορική διατριβή ανήκει στο πλαίσιο της μηχανικής μάθησης και την ανάπτυξη μεθοδολογιών για την επεξεργασία και ανάλυση μονοδιάστατων και διδιάστατων εγκεφαλικών σημάτων. Πιο συγκεκριμένα, εστιάζεται: 1) στην μελέτη, επεξεργασία και ανάλυση εγκεφαλικών σημάτων ηλεκτροκορτικογραφήματος για τον εντοπισμό φωνητικής δραστηριοποίησης και την ταξινόμηση συλλαβών με σκοπό τον σχεδιασμό και ανάπτυξη ενός BCI συστήματος για την αποκατάσταση ασθενών με προβλήματα ομιλίας, 2) στην επεξεργασία εικόνων μαγνητικής τομογραφίας εγκεφάλου με σκοπό την τμηματοποίηση και ταξινόμηση καρκινικών εγκεφαλικών όγκων, και 3) την μαθηματική μοντελοποίηση δικτύων βιολογικών νευρώνων.


Author(s):  
Oleksandr Dudin ◽  
◽  
Ozar Mintser ◽  
Oksana Sulaieva ◽  
◽  
...  

Introduction. Over the past few decades, thanks to advances in algorithm development, the introduction of available computing power, and the management of large data sets, machine learning methods have become active in various fields of life. Among them, deep learning possesses a special place, which is used in many spheres of health care and is an integral part and prerequisite for the development of digital pathology. Objectives. The purpose of the review was to gather the data on existing image analysis technologies and machine learning tools developed for the whole-slide digital images in pathology. Methods: Analysis of the literature on machine learning methods used in pathology, staps of automated image analysis, types of neural networks, their application and capabilities in digital pathology was performed. Results. To date, a wide range of deep learning strategies have been developed, which are actively used in digital pathology, and demonstrated excellent diagnostic accuracy. In addition to diagnostic solutions, the integration of artificial intelligence into the practice of pathomorphological laboratory provides new tools for assessing the prognosis and prediction of sensitivity to different treatments. Conclusions: The synergy of artificial intelligence and digital pathology is a key tool to improve the accuracy of diagnostics, prognostication and personalized medicine facilitation


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