scholarly journals ARTIFICIAL INTELLIGENCE AND NEXT GENERATION PATHOLOGY: TOWARDS PERSONALIZED MEDICINE

Author(s):  
Oleksandr Dudin ◽  
◽  
Ozar Mintser ◽  
Oksana Sulaieva ◽  
◽  
...  

Introduction. Over the past few decades, thanks to advances in algorithm development, the introduction of available computing power, and the management of large data sets, machine learning methods have become active in various fields of life. Among them, deep learning possesses a special place, which is used in many spheres of health care and is an integral part and prerequisite for the development of digital pathology. Objectives. The purpose of the review was to gather the data on existing image analysis technologies and machine learning tools developed for the whole-slide digital images in pathology. Methods: Analysis of the literature on machine learning methods used in pathology, staps of automated image analysis, types of neural networks, their application and capabilities in digital pathology was performed. Results. To date, a wide range of deep learning strategies have been developed, which are actively used in digital pathology, and demonstrated excellent diagnostic accuracy. In addition to diagnostic solutions, the integration of artificial intelligence into the practice of pathomorphological laboratory provides new tools for assessing the prognosis and prediction of sensitivity to different treatments. Conclusions: The synergy of artificial intelligence and digital pathology is a key tool to improve the accuracy of diagnostics, prognostication and personalized medicine facilitation

Author(s):  
Keiko Itano ◽  
Koji Ochiai ◽  
Koichi Takahashi ◽  
Takahide Matsushima ◽  
Hiroshi Asahara

Abstract In many biological laboratories, biologists analyze images and identify cell or organ states manually. There are some problems: lack of human resource and high experimental costs, among others. Identification results vary according to the person. To solve these problems, the process automation of biologists’ operations and quantitative identification are needed. Here, a cell-foci-phenotype identification system is developed by applying image processing and machine learning methods to fluorescent cell images. With this system, cell-foci-phenotype with high accuracy can be predicted and biologists’ efforts in doing image analysis can be reduced.


Energies ◽  
2021 ◽  
Vol 14 (15) ◽  
pp. 4595
Author(s):  
Parisa Asadi ◽  
Lauren E. Beckingham

X-ray CT imaging provides a 3D view of a sample and is a powerful tool for investigating the internal features of porous rock. Reliable phase segmentation in these images is highly necessary but, like any other digital rock imaging technique, is time-consuming, labor-intensive, and subjective. Combining 3D X-ray CT imaging with machine learning methods that can simultaneously consider several extracted features in addition to color attenuation, is a promising and powerful method for reliable phase segmentation. Machine learning-based phase segmentation of X-ray CT images enables faster data collection and interpretation than traditional methods. This study investigates the performance of several filtering techniques with three machine learning methods and a deep learning method to assess the potential for reliable feature extraction and pixel-level phase segmentation of X-ray CT images. Features were first extracted from images using well-known filters and from the second convolutional layer of the pre-trained VGG16 architecture. Then, K-means clustering, Random Forest, and Feed Forward Artificial Neural Network methods, as well as the modified U-Net model, were applied to the extracted input features. The models’ performances were then compared and contrasted to determine the influence of the machine learning method and input features on reliable phase segmentation. The results showed considering more dimensionality has promising results and all classification algorithms result in high accuracy ranging from 0.87 to 0.94. Feature-based Random Forest demonstrated the best performance among the machine learning models, with an accuracy of 0.88 for Mancos and 0.94 for Marcellus. The U-Net model with the linear combination of focal and dice loss also performed well with an accuracy of 0.91 and 0.93 for Mancos and Marcellus, respectively. In general, considering more features provided promising and reliable segmentation results that are valuable for analyzing the composition of dense samples, such as shales, which are significant unconventional reservoirs in oil recovery.


2021 ◽  
Author(s):  
Timo Kumpula ◽  
Janne Mäyrä ◽  
Anton Kuzmin ◽  
Arto Viinikka ◽  
Sonja Kivinen ◽  
...  

<p>Sustainable forest management increasingly highlights the maintenance of biological diversity and requires up-to-date information on the occurrence and distribution of key ecological features in forest environments. Different proxy variables indicating species richness and quality of the sites are essential for efficient detecting and monitoring forest biodiversity. European aspen (Populus tremula L.) is a minor deciduous tree species with a high importance in maintaining biodiversity in boreal forests. Large aspen trees host hundreds of species, many of them classified as threatened. However, accurate fine-scale spatial data on aspen occurrence remains scarce and incomprehensive.</p><p> </p><p>We studied detection of aspen using different remote sensing techniques in Evo, southern Finland. Our study area of 83 km<sup>2</sup> contains both managed and protected southern boreal forests characterized by Scots pine (Pinus sylvestris L.), Norway spruce (Picea abies (L.) Karst), and birch (Betula pendula and pubescens L.), whereas European aspen has a relatively sparse and scattered occurrence in the area. We collected high-resolution airborne hyperspectral and airborne laser scanning data covering the whole study area and ultra-high resolution unmanned aerial vehicle (UAV) data with RGB and multispectral sensors from selected parts of the area. We tested the discrimination of aspen from other species at tree level using different machine learning methods (Support Vector Machines, Random Forest, Gradient Boosting Machine) and deep learning methods (3D convolutional neural networks).</p><p> </p><p>Airborne hyperspectral and lidar data gave excellent results with machine learning and deep learning classification methods The highest classification accuracies for aspen varied between 91-92% (F1-score). The most important wavelengths for discriminating aspen from other species included reflectance bands of red edge range (724–727 nm) and shortwave infrared (1520–1564 nm and 1684–1706 nm) (Viinikka et al. 2020; Mäyrä et al 2021). Aspen detection using RGB and multispectral data also gave good results (highest F1-score of aspen = 87%) (Kuzmin et al 2021). Different remote sensing data enabled production of a spatially explicit map of aspen occurrence in the study area. Information on aspen occurrence and abundance can significantly contribute to biodiversity management and conservation efforts in boreal forests. Our results can be further utilized in upscaling efforts aiming at aspen detection over larger geographical areas using satellite images.</p>


2019 ◽  
Vol 11 (2) ◽  
pp. 196 ◽  
Author(s):  
Omid Ghorbanzadeh ◽  
Thomas Blaschke ◽  
Khalil Gholamnia ◽  
Sansar Meena ◽  
Dirk Tiede ◽  
...  

There is a growing demand for detailed and accurate landslide maps and inventories around the globe, but particularly in hazard-prone regions such as the Himalayas. Most standard mapping methods require expert knowledge, supervision and fieldwork. In this study, we use optical data from the Rapid Eye satellite and topographic factors to analyze the potential of machine learning methods, i.e., artificial neural network (ANN), support vector machines (SVM) and random forest (RF), and different deep-learning convolution neural networks (CNNs) for landslide detection. We use two training zones and one test zone to independently evaluate the performance of different methods in the highly landslide-prone Rasuwa district in Nepal. Twenty different maps are created using ANN, SVM and RF and different CNN instantiations and are compared against the results of extensive fieldwork through a mean intersection-over-union (mIOU) and other common metrics. This accuracy assessment yields the best result of 78.26% mIOU for a small window size CNN, which uses spectral information only. The additional information from a 5 m digital elevation model helps to discriminate between human settlements and landslides but does not improve the overall classification accuracy. CNNs do not automatically outperform ANN, SVM and RF, although this is sometimes claimed. Rather, the performance of CNNs strongly depends on their design, i.e., layer depth, input window sizes and training strategies. Here, we conclude that the CNN method is still in its infancy as most researchers will either use predefined parameters in solutions like Google TensorFlow or will apply different settings in a trial-and-error manner. Nevertheless, deep-learning can improve landslide mapping in the future if the effects of the different designs are better understood, enough training samples exist, and the effects of augmentation strategies to artificially increase the number of existing samples are better understood.


2019 ◽  
Vol 2019 ◽  
pp. 1-12 ◽  
Author(s):  
Yan Wang ◽  
Hao Zhang ◽  
Zhanliang Sang ◽  
Lingwei Xu ◽  
Conghui Cao ◽  
...  

Automatic modulation recognition has successfully used various machine learning methods and achieved certain results. As a subarea of machine learning, deep learning has made great progress in recent years and has made remarkable progress in the field of image and language processing. Deep learning requires a large amount of data support. As a communication field with a large amount of data, there is an inherent advantage of applying deep learning. However, the extensive application of deep learning in the field of communication has not yet been fully developed, especially in underwater acoustic communication. In this paper, we mainly discuss the modulation recognition process which is an important part of communication process by using the deep learning method. Different from the common machine learning methods that require feature extraction, the deep learning method does not require feature extraction and obtains more effects than common machine learning.


2021 ◽  
Author(s):  
Andreas Sepp

Artificial intelligence and machine learning methods had significant contribution to the advancement and progress of predictive analytics. This article presents a state of the art of methods and applications of artificial intelligence and machine learning.


Sign in / Sign up

Export Citation Format

Share Document