scholarly journals Management of Endocrinopathies in Pregnancy: A Review of Current Evidence

2019 ◽  
Vol 16 (5) ◽  
pp. 781 ◽  
Author(s):  
Daniela Calina ◽  
Anca Docea ◽  
Kirill Golokhvast ◽  
Stavros Sifakis ◽  
Aristides Tsatsakis ◽  
...  
Keyword(s):  
Side Effects ◽  
Correct Diagnosis ◽  
Assisted Reproductive Techniques ◽  
Current Evidence ◽  
Thyroid Disorders ◽  
Adverse Side Effects ◽  
Pituitary Dysfunction ◽  
Reproductive Techniques ◽  
Parathyroid Disease ◽  
In Pregnancy

Pregnancy in women with associated endocrine conditions is a therapeutic challenge for clinicians. These disorders may be common, such us thyroid disorders and diabetes, or rare, including adrenal and parathyroid disease and pituitary dysfunction. With the development of assisted reproductive techniques, the number of pregnancies with these conditions has increased. It is necessary to recognize symptoms and correct diagnosis for a proper pharmacotherapeutic management in order to avoid adverse side effects both in mother and fetus. This review summarizes the pharmacotherapy of these clinical situations in order to reduce maternal and fetal morbidity.

scholarly journals Assessment of Thyroid Function in Early Pregnancy

2018 ◽  
Vol 19 (2) ◽  
pp. 98
Author(s):  
Mohammad Saifur Rahman ◽  
Sadia Sultana ◽  
Ayesha Nazneen
Keyword(s):  
Pregnant Women ◽  
Thyroid Function ◽  
Early Pregnancy ◽  
Correct Diagnosis ◽  
First Trimester ◽  
Military Hospital ◽  
Thyroid Disorders ◽  
Thyroid Disorder ◽  
Cross Sectional ◽  
In Pregnancy

<p><strong>Objectives:  </strong>Thyroid disorders are commonly observed in pregnancy. Thyroid hormones play an important role in embryogenesis and fetal development. The fetus is completely dependent on the mother for thyroid hormone in first trimester. About 10% of all pregnant women can be affected by thyroid disorders during pregnancy. Thyroid function abnormalities in pregnancy are a challenge for the concerned physicians.  The objective of this study was to assess the maternal thyroid function in first trimester of pregnancy.</p><p><strong>Patients and Methods: </strong>A descriptive cross sectional study was carried out at the Combined Military Hospital (CMH), Dhaka over a period of one year from January 2013 to December 2013 to see the serum FT<sub>3</sub>, FT<sub>4</sub>, TSH, thyroid antibodies level and common thyroid disorders in pregnancy. A total of 138 pregnant women in their first trimester (up to 12 weeks) of pregnancy with an age range of 18-35 years were enrolled in this study. Pregnant women with known thyroid disorder and on treatment and pregnancy more than three months were excluded. Measurement of serum FT<sub>3</sub>, FT<sub>4</sub>, TSH, Anti TPO-Ab and Anti TG-Ab were done in each patient at the time of enrolment. Ultrasonography of each patient was done for confirmation of pregnancy and correlation of gestational age.</p><p><strong>Results:  </strong>Among 138 pregnant women, subclinical hypothyroidism was detected in 10 (7.2%) patients and subclinical hyperthyroidism was detected in 3 (2.2%) patients. Mean difference of the investigation findings were not statistically significant among primi and multi gravida. TPO-Ab and TG-Ab difference were statistically significant between two age groups.</p><p><strong>Conclusion: </strong>Subclinical thyroid disorders are fairly high among pregnant women. Correct diagnosis in early pregnancy and prompt treatment will bring an excellent prognosis for both mother and offspring.</p><p>Bangladesh J. Nuclear Med. 19(2): 98-102, July 2016</p>

scholarly journals Procriação Assistida em Mulheres Transplantadas: Experiência de uma Unidade de Medicina da Reprodução e Revisão da Literatura

2016 ◽  
Vol 29 (1) ◽  
pp. 73
Author(s):  
Emídio Vale-Fernandes ◽  
Ana Margarida Póvoa ◽  
Sandra Soares ◽  
Lucinda Calejo ◽  
Pedro Xavier ◽  
...  
Keyword(s):  
Solid Organ Transplantation ◽  
Assisted Reproductive Techniques ◽  
Reproductive Capacity ◽  
Infertile Woman ◽  
Solid Organ ◽  
Reproductive Techniques ◽  
The Right ◽  
End Stage ◽  
De Medicina ◽  
In Pregnancy

<p>Diseases in end stage typically occur with hypothalamic-pituitary-ovarian axis disorders, with consequent anovulation and infertility. The solid organ transplantation increased survival of patients with end-stage organs disease and the vast majority of women improve their reproductive capacity after transplantation. Although adoption can always be a possibility, the transplanted infertile woman has the right to self-reproductive determination using assisted reproductive techniques. While it is known that pregnancies in transplanted<br />women are at high risk, there is no evidence of differences in pregnancy outcome in pregnant transplanted subject to technical, compared with spontaneous pregnancies. The use of assisted reproductive techniques in transplanted women is a medical, ethical and psychosocial challenge, whose approach must be multidisciplinary, to ensure reproductive success without compromising the function of the transplanted organ or maternal health, allowing the birth of a healthy child. The literature remains scarce. Three clinical cases are presented.</p>

scholarly journals Procriação Assistida em Mulheres Transplantadas: Experiência de uma Unidade de Medicina da Reprodução e Revisão da Literatura

2016 ◽  
Vol 29 (1) ◽  
pp. 73
Author(s):  
Emídio Vale-Fernandes ◽  
Ana Margarida Póvoa ◽  
Sandra Soares ◽  
Lucinda Calejo ◽  
Pedro Xavier ◽  
...  
Keyword(s):  
Solid Organ Transplantation ◽  
Assisted Reproductive Techniques ◽  
Reproductive Capacity ◽  
Infertile Woman ◽  
Solid Organ ◽  
Reproductive Techniques ◽  
The Right ◽  
End Stage ◽  
De Medicina ◽  
In Pregnancy

<p>Diseases in end stage typically occur with hypothalamic-pituitary-ovarian axis disorders, with consequent anovulation and infertility. The solid organ transplantation increased survival of patients with end-stage organs disease and the vast majority of women improve their reproductive capacity after transplantation. Although adoption can always be a possibility, the transplanted infertile woman has the right to self-reproductive determination using assisted reproductive techniques. While it is known that pregnancies in transplanted<br />women are at high risk, there is no evidence of differences in pregnancy outcome in pregnant transplanted subject to technical, compared with spontaneous pregnancies. The use of assisted reproductive techniques in transplanted women is a medical, ethical and psychosocial challenge, whose approach must be multidisciplinary, to ensure reproductive success without compromising the function of the transplanted organ or maternal health, allowing the birth of a healthy child. The literature remains scarce. Three clinical cases are presented.</p>

scholarly journals Folate supplementation in pregnancy

2021 ◽  
Vol 9 (05) ◽  
pp. 363-367
Author(s):  
Dr. Yasser Al-Ankoodi
Keyword(s):  
Side Effects ◽  
Folate Intake ◽  
Food Fortification ◽  
Folate Level ◽  
Folate Supplementation ◽  
Folate Status ◽  
Adverse Side Effects ◽  
Folate Supplement ◽  
Chemical Analyzer ◽  
In Pregnancy

Objectives: To determine the prevalence of low, normal and high folate levels in Omani population. Folate supplement given routinely during pregnancy. Folate added into multi-vitamins supplement as well as into food products. This leads to decrease the prevalence of low folate or increase prevalence of people with excess folate. Low and high folate level leads to adverse side effects. Methods: 3706 folate samples analyzed in Cobas e 601 chemical analyzer. The results separated into three main groups (low, normal and high). Results: Only 0.3% of the study sample shows low folate level. Five (0.2%) out of 2335 female samples show low folate level. Three (0.2%) out of 1371 male samples shows low folate level. Conclusion: Routine folate intake during pregnancy, supplement to the general population for wellbeing and food fortification might lead to excess folate status. Folate testing before supplementation help in avoiding high folate adverse effects.  

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