scholarly journals Synthesis, Structure-Activity Relationships (SAR) and in Silico Studies of Coumarin Derivatives with Antifungal Activity

2013 ◽  
Vol 14 (1) ◽  
pp. 1293-1309 ◽  
Author(s):  
Rodrigo de Araújo ◽  
Felipe Guerra ◽  
Edeltrudes de O. Lima ◽  
Carlos de Simone ◽  
Josean Tavares ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
In Silico ◽  
Coumarin Derivatives ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
In Silico Studies

Synthesis, pharmacological assessment, molecular modeling and in silico studies of fused tricyclic coumarin derivatives as a new family of multifunctional anti-Alzheimer agents

2016 ◽  
Vol 107 ◽  
pp. 219-232 ◽  
Author(s):  
Jeelan Basha Shaik ◽  
Bhagath Kumar Palaka ◽  
Mohan Penumala ◽  
Kasi Viswanath Kotapati ◽  
Subba Rao Devineni ◽  
...  
Keyword(s):  
Molecular Modeling ◽  
In Silico ◽  
Coumarin Derivatives ◽  
New Family ◽  
In Silico Studies

Evaluation of antifungal activities and structure-activity relationships of coumarin derivatives

2016 ◽  
Vol 73 (1) ◽  
pp. 94-101 ◽  
Author(s):  
Ping-Ping Song ◽  
Jun Zhao ◽  
Zong-Liang Liu ◽  
Ya-Bing Duan ◽  
Yi-Ping Hou ◽  
...  
Keyword(s):  
Coumarin Derivatives ◽  
Antifungal Activities ◽  
Structure Activity Relationships ◽  
Structure Activity

scholarly journals Design, characterization, in vitro antibacterial, antitubercular evaluation and structure–activity relationships of new hydrazinyl thiazolyl coumarin derivatives

2017 ◽  
Vol 26 (6) ◽  
pp. 1139-1148 ◽  
Author(s):  
Samina KhanYusufzai ◽  
Hasnah Osman ◽  
Mohammad Shaheen Khan ◽  
Suriyati Mohamad ◽  
Othman Sulaiman ◽  
...  
Keyword(s):  
Coumarin Derivatives ◽  
Structure Activity Relationships ◽  
Structure Activity

ChemInform Abstract: Derivatives of a Novel Cyclopeptolide. Part 1. Synthesis, Antifungal Activity, and Structure-Activity Relationships.

ChemInform ◽  
2010 ◽  
Vol 25 (50) ◽  
pp. no-no
Author(s):  
G. EMMER ◽  
M. A. GRASSBERGER ◽  
J. G. MEINGASSNER ◽  
G. SCHULZ ◽  
M. SCHAUDE
Keyword(s):  
Antifungal Activity ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Derivatives Of

Bis-coumarin Derivatives and Their Biological Activities

2018 ◽  
Vol 18 (2) ◽  
pp. 101-113 ◽  
Author(s):  
Qing-Cheng Ren ◽  
Chuan Gao ◽  
Zhi Xu ◽  
Lian-Shun Feng ◽  
Ming-Liang Liu ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Active Sites ◽  
Noncovalent Interactions ◽  
Biological Activities ◽  
Coumarin Derivatives ◽  
Antitumor Activities ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Biological Potential

Bis-coumarins have caused great interests in the recent years. These compounds exhibit diverse biological activities which are ascribed to their ability to exert noncovalent interactions with the various active sites in organisms. Some of them such as dicoumarolum and dicoumarol were approved for therapeutic purposes in clinical practice. Encouraged by the above facts, numerous biscoumarin derivatives have been synthesized and screened for their biological activities, and many of them showed promising potency. This review is focused on the biological potential of bis-coumarin derivatives with particular mention of those exhibiting antibacterial, anticoagulant, antiinflammatory, antiviral, anti-parasite and antitumor activities, and their structure-activity relationships are also discussed.

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