scholarly journals Gender Differences in Health-Related Quality of Life in Patients with Systolic Heart Failure: Results of the VIDA Multicenter Study

2020 ◽  
Vol 9 (9) ◽  
pp. 2825
Author(s):  
Alberto Garay ◽  
Javier Tapia ◽  
Manuel Anguita ◽  
Francesc Formiga ◽  
Luis Almenar ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Gender Differences ◽  
Statistical Significance ◽  
Systolic Heart Failure ◽  
Health Related Quality ◽  
Related Factors ◽  
Related Quality ◽  
Health Related

Previous studies have shown that heart failure is associated with worse health-related quality of life (HRQoL). The existence of differences according to gender remains controversial. We studied 1028 consecutive outpatients with heart failure and reduced ejection fraction (HFrEF) from a multicentre cross-sectional descriptive study across Spain that assessed HRQoL using two questionnaires (KCCQ, Kansas City Cardiomyopathy Questionnaire; and EQ-5D, EuroQoL 5 dimensions). The primary objective of the study was to describe differences in HRQoL between men and women in global scores and domains of health status of patients and explore gender differences and its interactions with heart failure related factors. In adjusted analysis women had lower scores in KCCQ overall summary scores when compared to men denoting worse HRQoL (54.7 ± 1.3 vs. 62.7 ± 0.8, p < 0.0001), and specifically got lower score in domains of symptom frequency, symptoms burden, physical limitation, quality of life and social limitation. No differences were found in domains of symptom stability and self-efficacy. Women also had lower scores on all items of EQ-5D (EQ-5D index 0.58 ± 0.01 vs. 0.67 ± 0.01, p < 0.0001). Finally, we analyzed interaction between gender and different clinical determinants regarding the presence of limitations in the 5Q-5D and overall summary score of KCCQ. Interestingly, there was no statistical significance for interaction for any variable. In conclusion, women with HFrEF have worse HRQoL compared to men. These differences do not appear to be mediated by clinical or biological factors classically associated with HRQoL nor with heart failure severity.

scholarly journals Health-related Quality of Life of Patients With Chronic Systolic Heart Failure in Spain: Results of the VIDA-IC Study

2016 ◽  
Vol 69 (3) ◽  
pp. 256-271 ◽  
Author(s):  
Josep Comín-Colet ◽  
Manuel Anguita ◽  
Francesc Formiga ◽  
Luis Almenar ◽  
María G. Crespo-Leiro ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Systolic Heart Failure ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Chronic Systolic Heart Failure

scholarly journals Health-related quality of life and long-term morbidity and mortality in patients hospitalised with systolic heart failure

2014 ◽  
Vol 3 ◽  
pp. 204800401454873 ◽  
Author(s):  
Jenny Berg ◽  
Peter Lindgren ◽  
Thomas Kahan ◽  
Owe Schill ◽  
Hans Persson ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Systolic Heart Failure ◽  
Morbidity And Mortality ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

scholarly journals Gender differences in health-related quality of life among coronary patients and the relation with comorbidity burden. Results from the ESC EORP EUROASPIRE V survey

2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
P Vynckier ◽  
L Van Wilder ◽  
S Gevaert ◽  
D De Bacquer ◽  
D De Smedt ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Gender Differences ◽  
Index Score ◽  
Health Related Quality ◽  
Comorbidity Burden ◽  
Related Quality ◽  
Health Related ◽  
History Of

Abstract Background Impaired health-related quality of life (HRQoL) is related to increased morbidity and mortality among coronary heart disease (CHD) patients. Although gender differences in HRQoL have been observed in the general population, the magnitude of gender differences tends to be more pronounced in CHD patients. In addition, a higher comorbidity burden, common in CHD patients, is known to result in an even worse HRQoL outcome. Purpose The aim of this study is to evaluate HRQoL- gender differences among CHD patients and to explore its relationship with comorbidity burden. Methods Analyses were based on the most recent ESC EORP EUROASPIRE V survey data, including patient information from 27 European countries. Consecutive patients (18–80 years), hospitalized for a coronary event or surgical procedure were recruited in the survey. Data presented here were obtained from medical records and standardized patient interviews (6 months to 2 years following hospital discharge). Mean EQ-5D-5L index scores were used to evaluate patients' self-reported health status. A history of stroke, heart failure, peripheral artery disease (PAD), chronic kidney disease (CKD), and self-reported diabetes were considered as comorbidities. Generalized linear mixed models were fitted accounting for clustering of patients within countries and adjusted for age. To investigate the interplay of gender with comorbidities, two-way interaction terms were included. Results Data was available for 8,261 patients, including 25.8% women. Women were slightly older than men (65.4 vs 63.0 years) and more likely to have a history of stroke (5.3% vs. 3.7%; p=0.04), heart failure (7.6% vs. 5.9%; p=0.02), and self-reported diabetes (33.1% vs. 28.0%; p&lt;0.001). No significant differences were seen in the prevalences of PAD (2.5% vs. 2.7%; p=0.25) and CKD (13.8% vs. 14.5%; p=0.47). Overall, women reported a worse EQ-5D-5L index score compared to men (0.73 vs. 0.81; p&lt;0.001). Also, considering CHD patients without comorbidities, women reported a worse EQ-5D-5L index score (0.77 vs. 0.84; p&lt;0.001). Stratification by comorbidities revealed that the EQ-5D-5L index score differed substantially between genders. Although no gender differences were found for patients with PAD (0.62 vs. 0.68; p=0.13), women reported a worse EQ-5D-5L index score if having a history of stroke (0.59 vs. 0.69; p&lt;0.001), heart failure (0.64 vs. 0.71; p=0.01), CKD (0.76 vs. 0.81; p&lt;0.001), and self-reported diabetes (0.69 vs. 0.78; p&lt;0.001). Moreover, detailed analyses revealed a significant interaction between gender and self-reported diabetes (p=0.04) and gender and CKD (p=0.04) in favour of women. A closer look at the combination of comorbidities revealed no significant interactions possibly due to the smaller number of patients. Conclusion Women reported a worse HRQoL compared to men. Further quantitative and qualitative research is needed to understand the gender-differential in HRQoL. FUNDunding Acknowledgement Type of funding sources: Public Institution(s). Main funding source(s): Fonds voor hartchirurgie - Fonds pour la Chirurgie Cardiaque

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