scholarly journals Chronic Kidney Disease and Its Relationship with Mental Health: Allostatic Load Perspective for Integrated Care

2021 ◽  
Vol 11 (12) ◽  
pp. 1367
Author(s):  
Federica Guerra ◽  
Dina Di Giacomo ◽  
Jessica Ranieri ◽  
Marilena Tunno ◽  
Luca Piscitani ◽  
...  

Background: Chronic renal failure is a chronic medical condition characterized by a progressive and irreversible loss of kidney function. Up to 50% of patients undergoing dialysis experience symptoms of depression and anxiety: what is the impact of individual factors and medical conditions on the mental health issue? The present study was carried out to investigate the individual factors (biomarkers and psychological dimensions) of end-stage renal disease patients dealing with dialysis, analyzing their predictor values for developing negative disease adaptations by an allostatic paradigm. Methods: We conducted an observational study on 35 patients affected by end-stage renal disease; biological and psychological markers have been detected. We conducted descriptive statistical analyses (t-tests) and performed a hierarchical regression analysis to investigate the relationship between pathological medical conditions and psychological dimensions. Results: The findings showed a positive correlation between creatinine levels and psychological distress as well as stress index. No significant effect of “time of dialysis”, “time from diagnosis”, “age” and “personality traits” was found. Conclusion: Our findings showed that personality traits did not represent a protective factor by moderating positive emotional adaptations; conversely, creatinine levels appeared predictive for negative emotional adaptations. High levels of creatinine were found to be positively associated with high stress levels as well psychological distress. According to the allostatic paradigm, end-stage renal disease patients could experience an allostatic load and more overload towards poor health outcomes; integrated biological and psychological measurements could prevent increased negative mental health through a patient-centered approach.

2018 ◽  
Vol 25 (12) ◽  
pp. 1978-1988 ◽  
Author(s):  
Luca Iani ◽  
Marco Lauriola ◽  
Andrea-René Angeramo ◽  
Elena Malinconico ◽  
Piero Porcelli

In this preliminary study, we examined whether aspects of spiritual well-being accounted for mental and physical health-related quality of life in 68 patients with end-stage renal disease, when controlling for age, type of treatment, physical symptoms, and worries. Hierarchical multiple regressions showed that meaning was associated with better mental health, while worry and physical symptoms also accounted for poor mental health. Faith and peace did not contribute to mental health. Older age, type of treatment (hemodialysis), and physical symptoms accounted for poor physical health. Our findings suggest that clinicians should include spiritual well-being in future interventions for end-stage renal disease patients.


PeerJ ◽  
2020 ◽  
Vol 8 ◽  
pp. e8713
Author(s):  
Qi Wang ◽  
Hongjian Liu ◽  
Zheng Ren ◽  
Wenjing Xiong ◽  
Minfu He ◽  
...  

Objectives The study aimed to explore the association of coping styles and social support with psychological distress among patients with end-stage renal disease (ESRD) as well as gender differences in these associations. Methods A cross-sectional study of 769 ESRD patients was conducted at 25 hospitals in Qiqihar City, China. All information was collected using structured questionnaires that were self-administered by the patients. Patients’ psychological health status, coping styles and perceived social support were measured using the 12-item General Health Questionnaire, the Medical Coping Modes Questionnaire and the Multidimensional Scale of Perceived Social Support. Student’s t test, analysis of variance (ANOVA) and binary logistic regression analysis were used for data analysis. Results A total of 72.3% of participants reported psychological distress, and the prevalence of distress was higher in females (77.0%) than in males (68.8%). The usage of the acceptance-resignation coping style was positively related to psychological distress (B = 0.459, P < 0.001). Social support level was negatively associated with psychological distress (B = −0.049, P < 0.001). The use of the confrontation style was negatively related to psychological distress in females (OR = 0.87, 95% CI [0.78–0.96]) but not in males (OR = 0.98, 95% CI [0.91–1.06]) (P for interaction term = 0.007). Conclusions Greater use of the acceptance-resignation style and lower social support are related to a higher risk of psychological distress. Greater use of the confrontation style is related to a lower risk of psychological distress in females but not in males.


2008 ◽  
Vol 47 (169) ◽  
Author(s):  
Shailendra Shrestha ◽  
L R Ghotekar ◽  
S K Sharma ◽  
P M Shangwa ◽  
P Karki

This study was conducted to measure quality of life of patients with end stage renal disease ondifferent modalities of treatment.A total of 30 diagnosed cases of end stage renal disease (ESRD) attending BPKIHS were includedin the study. Group 1 included 10 patients on regular maintenance hemodialysis, group 2 included10 patients on continuous ambulatory peritoneal dialysis (CAPD) and group 3 included 10 patientson regular conservative drugs. The inclusion criteria were all diagnosed cases of ESRD based on theguidelines given by K/DOQI, 2002. A detailed history relating to the disease condition as per thedesigned proforma was taken, which included demographic data and clinical characteristics of thepatients. For assessment of quality of life, KDQOL-SF questionnaire was used. Strata 8.0 softwareprogram was used for the analysis of collected data.Physical health was found to be the most severely affected domain of the KDQOL. The mean scorefor physical health was least in group 1 (33.36 ± 16.14). Mental health was better in group 2 (54.93± 9.92) than in group 1 (39.50 ± 14.27) ( “p” value 0.01). Variables like haemoglobin, hematocrit andadequacy of dialysis have positive correlation with all the four domains of the KDQOL. There wasa statistically signifi cant correlation of physical health with mental health (p value 0.001), physicalhealth with kidney disease issues (p value 0.001) and mental health with kidney disease issues (pvalue 0.007).Our study has shown that patients of ESRD have a poor quality of life despite being in some formof dialysis and the most affected domain of the KDQOL scale is physical health. Patients on CAPDhave better quality of life than patients on maintenance haemodialysis especially in terms of mentalhealth. Variables like haemoglobin, hematocrit and adequacy of dialysis have a positive correlationwith all the four domains of the KDQOL scale i.e. optimizing these variables improves the overallquality of life.Key Words: dialysis, end stage renal disease, quality of lifeCorrespondence:


1977 ◽  
Vol 7 (2) ◽  
pp. 179-192 ◽  
Author(s):  
Dennis Drotar ◽  
Mary Ann Ganofsky

The increasing number of pediatric patients with end-stage renal disease who undergo dialysis and transplantation have necessitated the development of psychological interventions to lessen the emotional impact of these procedures. This report describes the dilemmas involved in mental health interventions and consultation in a treatment program for end-stage renal disease. Case illustrations of a young child's severe anxiety reaction to dialysis, an adolescent's depression, and a family's withdrawal document the varied patterns of adaptation to treatment for renal failure. Psychotherapeutic approaches are presented to illustrate the flexible use of a number of treatment modalities including brief crisis-oriented intervention which emphasizes the patient's cognitive mastery of procedures. The development of viable mechanisms of professional collaboration improves the quality of patient adaptation by lessening the fragmentation of care and problems of interdisciplinary communication often associated with the medical care of children and adolescents with end-stage renal failure.


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