scholarly journals Hydrogel, Electrospun and Composite Materials for Bone/Cartilage and Neural Tissue Engineering

Materials ◽  
2021 ◽  
Vol 14 (22) ◽  
pp. 6899
Author(s):  
Beata Niemczyk-Soczynska ◽  
Angelika Zaszczyńska ◽  
Konrad Zabielski ◽  
Pawel Sajkiewicz

Injuries of the bone/cartilage and central nervous system are still a serious socio-economic problem. They are an effect of diversified, difficult-to-access tissue structures as well as complex regeneration mechanisms. Currently, commercially available materials partially solve this problem, but they do not fulfill all of the bone/cartilage and neural tissue engineering requirements such as mechanical properties, biochemical cues or adequate biodegradation. There are still many things to do to provide complete restoration of injured tissues. Recent reports in bone/cartilage and neural tissue engineering give high hopes in designing scaffolds for complete tissue regeneration. This review thoroughly discusses the advantages and disadvantages of currently available commercial scaffolds and sheds new light on the designing of novel polymeric scaffolds composed of hydrogels, electrospun nanofibers, or hydrogels loaded with nano-additives.

2012 ◽  
Vol 27 (4) ◽  
pp. 369-390 ◽  
Author(s):  
TY Wang ◽  
JS Forsythe ◽  
CL Parish ◽  
DR Nisbet

Nanoscale ◽  
2010 ◽  
Vol 2 (1) ◽  
pp. 35-44 ◽  
Author(s):  
Jingwei Xie ◽  
Matthew R. MacEwan ◽  
Andrea G. Schwartz ◽  
Younan Xia

2013 ◽  
Vol 1 (1) ◽  
pp. 15-20 ◽  
Author(s):  
Jafar Ai ◽  
Anahita Kiasat-Dolatabadi ◽  
Somayeh Ebrahimi-Barough ◽  
Armin Ai ◽  
Nasrin Lotfibakhshaiesh ◽  
...  

2018 ◽  
Vol 29 (13) ◽  
pp. 1625-1642 ◽  
Author(s):  
Ryan J. Miller ◽  
Cheook Y. Chan ◽  
Arjun Rastogi ◽  
Allison M. Grant ◽  
Christina M. White ◽  
...  

ACS Omega ◽  
2021 ◽  
Author(s):  
Veronica A. Revkova ◽  
Konstantin V. Sidoruk ◽  
Vladimir A. Kalsin ◽  
Pavel A. Melnikov ◽  
Mikhail A. Konoplyannikov ◽  
...  

Polymers ◽  
2011 ◽  
Vol 3 (1) ◽  
pp. 413-426 ◽  
Author(s):  
Yee-Shuan Lee ◽  
Treena Livingston Arinzeh

Gels ◽  
2021 ◽  
Vol 8 (1) ◽  
pp. 25
Author(s):  
Devindraan Sirkkunan ◽  
Belinda Pingguan-Murphy ◽  
Farina Muhamad

Tissues are commonly defined as groups of cells that have similar structure and uniformly perform a specialized function. A lesser-known fact is that the placement of these cells within these tissues plays an important role in executing its functions, especially for neuronal cells. Hence, the design of a functional neural scaffold has to mirror these cell organizations, which are brought about by the configuration of natural extracellular matrix (ECM) structural proteins. In this review, we will briefly discuss the various characteristics considered when making neural scaffolds. We will then focus on the cellular orientation and axonal alignment of neural cells within their ECM and elaborate on the mechanisms involved in this process. A better understanding of these mechanisms could shed more light onto the rationale of fabricating the scaffolds for this specific functionality. Finally, we will discuss the scaffolds used in neural tissue engineering (NTE) and the methods used to fabricate these well-defined constructs.


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