scholarly journals Oral Conditions and Oral Health-Related Quality of Life of People with Ehlers-Danlos Syndromes (EDS): A Questionnaire-Based Cross-Sectional Study

Medicina ◽  
2020 ◽  
Vol 56 (9) ◽  
pp. 448 ◽  
Author(s):  
Marcel Hanisch ◽  
Moritz Blanck-Lubarsch ◽  
Lauren Bohner ◽  
Dominik Suwelack ◽  
Johannes Kleinheinz ◽  
...  

Background and objective: To date, there have only been a few studies on oral health-related quality of life (OHRQoL) of people with Ehlers–Danlos syndromes (EDS) and oral conditions. The aim of this study was, therefore, to analyze the OHRQoL of people with EDS from their own point of view as well as obtain information about their age at the time of the diagnosis, the period of time until diagnosis, and the presence of oral conditions (if any) and their association with oral health quality. Methods: The study was designed as an anonymous questionnaire-based cross-sectional study. We conducted a descriptive analysis of the Oral Health Impact Profile-14 (OHIP-14) scores, age of the participants, age at diagnosis, and the time-period between the first signs of the disease and the diagnosis of EDS. To verify the differences in OHIP-14 scores between patients with and without oral conditions, a Mann–Whitney U test was performed. A multivariate quantile (median) regression analysis was performed to evaluate the effect of different general characteristics (gender, age, and the presence of oral conditions) on the OHIP 14 scores. Furthermore, using a Mann–Whitney U test, the influence of different oral conditions was verified by testing the differences between patients without any oral conditions and patients with a specific diagnosis. Results: A total of 79 evaluable questionnaires from 66 female (83.5%) and 13 male (16.5%) participants were analyzed. On average, after the first condition, it takes 18.36 years before EDS are correctly diagnosed. Oral conditions were described by 69.6% of the participants. The median (interquartile range) OHIP-14 score was eight (ten) points for patients without oral conditions and 19 (15) for patients with oral conditions. The multivariable quantile regression shows a statistical notable association between OHIP-14 score and oral conditions (p < 0.001). OHIP-14 scores for dysgnathia, periodontitis, TMD (Temporomandibular dysfunction), a high-arched palate, malocclusion, and the anomaly of tooth formation were statistical notably different between the participants with and the participants without oral conditions. Conclusions: Long diagnostic pathways seem to be a typical problem in patients with EDS. Oral conditions associated with the underlying disease occurred regularly and showed a negative correlation with OHRQoL.

AIDS Care ◽  
2020 ◽  
pp. 1-8
Author(s):  
Rúben Teófilo Vasconcelos Moreira Rocha Trindade ◽  
Joana Rita Oliveira Faria Marques ◽  
Marcos Alberto Gil da Veiga ◽  
Duarte Nuno da Silva Marques ◽  
António Duarte Sola Pereira da Mata

2020 ◽  
Vol 12 (5) ◽  
pp. 210
Author(s):  
SandhyaP Naik ◽  
Sadananda Hota ◽  
Purnendu Bhushan ◽  
George Sam ◽  
VaradharajuVinutha Kumari ◽  
...  

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Raquel Conceição Ferreira ◽  
Ichiro Kawachi ◽  
João Gabriel Silva Souza ◽  
Fernanda Lamounier Campos ◽  
Loliza Luiz Figueiredo Houri Chalub ◽  
...  

2019 ◽  
Vol 28 (9) ◽  
pp. 2481-2489
Author(s):  
Taciana Mara Couto Silva ◽  
Levy Anderson César Alves ◽  
Deise Garrido ◽  
Andreia Watanabe ◽  
Fausto Medeiros Mendes ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document