scholarly journals 3-Benzoylisoxazolines by 1,3-Dipolar Cycloaddition: Chloramine-T-Catalyzed Condensation of α-Nitroketones with Dipolarophiles

Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3491
Author(s):  
Xinhui Pan ◽  
Xiaobing Xin ◽  
Ying Mao ◽  
Xin Li ◽  
Yanan Zhao ◽  
...  
Keyword(s):  
Low Cost ◽  
Dipolar Cycloaddition ◽  
Chloramine T

In this study, 3-benzoylisoxazolines were synthesized by reacting alkenes with various α-nitroketones using chloramine-T as the base. The scope of α-nitroketones and alkenes is extensive, including different alkenes and alkynes to form various isoxazolines and isoxazoles. The use of chloramine-T, as the low-cost, easily handled, moderate base for 1,3-dipolar cycloaddition is attractive.

1,3-Dipolar Cycloaddition of Dipolar Reagents to Bifunctional Olefins with Chloramine-T --- Part-II

2000 ◽  
Vol 30 (22) ◽  
pp. 4007-4016 ◽  
Author(s):  
V. Padmavathi ◽  
R. P. Sumathi ◽  
K. Venugopal Reddy ◽  
A. Somasekhar Reddy ◽  
D. Bhaskar Reddy
Keyword(s):  
Dipolar Cycloaddition ◽  
Chloramine T

scholarly journals An Efficient and Facile Synthesis of Novel Triazole C-N Linked Chromone Hybrids

2020 ◽  
Vol 32 (7) ◽  
pp. 1806-1808
Author(s):  
B. Kanakadurga Rao ◽  
Y. Jayaprakash Rao
Keyword(s):  
Spectral Analysis ◽  
Click Chemistry ◽  
Low Cost ◽  
Cost Effective ◽  
Dipolar Cycloaddition ◽  
Facile Synthesis ◽  
Mass Spectral Analysis ◽  
Mass Spectral ◽  
Molecular Hybrids

A series of new C3-N1 directly linked chromone/1,2,3-triazole molecular hybrids synthesized by adopting low cost effective CuI catalyzed azide-alkyne 1,3-dipolar cycloaddition (Cu-AAC triazole annulation) from chromone-3-aldehyde via key intermediates 3-azidochromone, synthesized from another intermediate 3-hydroxychromone. These synthetic 1,2,3-triazole embedded chromones are the new addition to the click chemistry family. The structures of final products established by IR, NMR and mass spectral analysis.

1,3-Dipolar Cycloaddition of Dipolar Reagents to Bifunctional Bis Olefins in the Presence of Chloramine-T

2003 ◽  
Vol 178 (1) ◽  
pp. 171-177 ◽  
Author(s):  
V. Padmavathi ◽  
K. Venugopal Reddy ◽  
A. Padmaja ◽  
D. Bhaskar Reddy
Keyword(s):  
Dipolar Cycloaddition ◽  
Chloramine T

CuI-Catalyzed [3+2] Cycloaddition of Hindered Vinylidenebisphosphonates (VBP) with Azomethine Imines for Highly Regioselective Access to Dinitrogen-Heterobicycle-Containing Bisphosphonates

Synthesis ◽  
2018 ◽  
Vol 50 (13) ◽  
pp. 2601-2607
Author(s):  
Zhongxiang Zhu ◽  
Qinghe Wang ◽  
Dulin Kong ◽  
Tiao Huang ◽  
Mingshu Wu
Keyword(s):  
Biological Activity ◽  
Low Cost ◽  
Cycloaddition Reaction ◽  
Dipolar Cycloaddition ◽  
Atom Economy ◽  
Mild Conditions ◽  
Synthetic Strategy ◽  
Fused Heterocycles ◽  
Azomethine Imines ◽  
High Stereoselectivity

A concise, atom-economic, and highly regioselective synthetic strategy for the construction of several dinitrogen-fused heterocycles bearing bisphosphonates by 1,3-dipolar cycloaddition reaction of azomethine imines with tetraethyl vinylidene-1,1-bisphosphonate in the presence of CuI in toluene media has been developed. The targeted compounds were obtained in good yields and with excellent regioselectivity. This method for the synthesis of gem-bisphosphonates (BPs) is particularly attractive due to features such as low cost, mild conditions, atom economy, high stereoselectivity, and potential biological activity of the product.

1,3-Dipolar Cycloaddition of Dipolar Reagents to Bischalcones in the Presence of Chloramine-T.

ChemInform ◽  
2005 ◽  
Vol 36 (5) ◽  
Author(s):  
V. Padmavathi ◽  
K. Venugopal Reddy ◽  
M. Rajagopala Sarma ◽  
R. P. Sumathi ◽  
D. Bhaskar Reddy
Keyword(s):  
Dipolar Cycloaddition ◽  
Chloramine T

ChemInform Abstract: 1,3-Dipolar Cycloaddition of Dipolar Reagents to Bifunctional Olefins with Chloramine-T. Part 2.

ChemInform ◽  
2001 ◽  
Vol 32 (4) ◽  
pp. no-no
Author(s):  
V. Padmavathi ◽  
R. P. Sumathi ◽  
K. Venugopal Reddy ◽  
A. Somasekhar Reddy ◽  
D. Bhaskar Reddy
Keyword(s):  
Dipolar Cycloaddition ◽  
Chloramine T

ChemInform Abstract: 1,3-Dipolar Cycloaddition of Dipolar Reagents to Bifunctional Olefins in the Presence of Chloramine-T (CAT).

ChemInform ◽  
2010 ◽  
Vol 31 (7) ◽  
pp. no-no
Author(s):  
V. Padmavathi ◽  
R. P. Sumathi ◽  
N. Chandrasekhar Babu ◽  
D. Bhaskar Reddy
Keyword(s):  
Dipolar Cycloaddition ◽  
Chloramine T

scholarly journals 1,3-Dipolar Cycloaddition of Dipolar Reagents to Bifunctional Olefins in the Presence of Chloramine-T (CAT)

1999 ◽  
Vol 23 (10) ◽  
pp. 610-611
Author(s):  
V. Padmavathi ◽  
R. P. Sumathi ◽  
N. Chandrasekhar Babu ◽  
D. Bhaskar Reddy
Keyword(s):  
Dipolar Cycloaddition ◽  
Chloramine T

2-Pyrazolines and 2-isoxazolines are prepared by the reaction of araldehyde hydrazones and araldoximes with bifunctional olefins in the presence of chloramine-T, which also functions as a reagent for aromatization of the former.

One-Pot Catalyst-Free Domino Condensation/Intramolecular 1,3-Dipolar Cycloaddition: Highly Stereoselective Access to Phosphadihydrocoumarin-Fused N,N-Bicyclic Pyrazolidin-3-ones

Synthesis ◽  
2017 ◽  
Vol 50 (01) ◽  
pp. 139-145 ◽  
Author(s):  
Mingshu Wu ◽  
Jie Jiang ◽  
Zhongxiang Zhu ◽  
Qinghe Wang ◽  
Dulin Kong
Keyword(s):  
Low Cost ◽  
Cycloaddition Reaction ◽  
Dipolar Cycloaddition ◽  
Nitrogen And Phosphorus ◽  
One Pot ◽  
Intramolecular Cycloaddition ◽  
Catalyst Free ◽  
Synthetic Strategy ◽  
The One ◽  
High Stereoselectivity

A concise, atom-economic, and highly regio/stereoselective synthetic strategy was developed for the construction of phosphorus- and nitrogen-fused polycyclic skeleton derivatives. The one-pot, two-step, catalyst-free domino condensation/intramolecular cycloaddition reaction of various substituted 2-(vinylphosphoryloxy)benzaldehydes with pyrazolidin-3-one took place at room temperature. Three new bonds (C–C, 2 × C–N) and two new nitrogen and phosphorus heterocycles were simultaneously constructed. The reaction is particularly attractive due to features such as low cost, mild conditions, atom economy, high stereoselectivity, and potential biological activity of the product.

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