scholarly journals Self-Assembled Triphenylphosphonium-Conjugated Dicyanostilbene Nanoparticles and Their Fluorescence Probes for Reactive Oxygen Species

Nanomaterials ◽  
2018 ◽  
Vol 8 (12) ◽  
pp. 1034
Author(s):  
Wonjin Choi ◽  
Na Lim ◽  
Heekyoung Choi ◽  
Moo Seo ◽  
Junho Ahn ◽  
...  

We report self-assembled novel triphenylphosphonium-conjugated dicyanostilbene-based as selective fluorescence turn-on probes for 1O2 and ClO−. Mono- or di-triphenylphosphonium-conjugated dicyanostilbene derivatives 1 and 2 formed spherical structures with diameters of ca. 27 and 56.5 nm, respectively, through π-π interaction between dicyanostilbene groups. Self-assembled 1 showed strong fluorescent emission upon the addition of 1O2 and ClO− compared to other ROS (O2−, •OH, NO, TBHP, H2O2, GSH), metal ions (K+, Na+), and amino acids (cysteine and histidine). Upon addition of 1O2 and ClO−, the spherical structure of 1 changed to a fiber structure (8-nm wide; 300-nm long). Upon addition of 1O2 and ClO−, the chemical structural conversion of 1 was determined by FAB-Mass, NMR, IR and Zeta potential analysis, and the strong emission of the self-assembled 1 was due to an aggregation-induced emission enhancement. This self-assembled material was the first for selective ROS as a fluorescence turn-on probe. Thus, a nanostructure change-derived turn-on sensing strategy for 1O2 or ClO− may offer a new approach to developing methods for specific guest molecules in biological and environmental subjects.

2019 ◽  
Vol 40 (1) ◽  
pp. 27-53 ◽  
Author(s):  
Meichen Guo ◽  
Hang Song ◽  
Kai Li ◽  
Minchao Ma ◽  
Yang Liu ◽  
...  

2017 ◽  
Vol 9 (6) ◽  
pp. 5118-5127 ◽  
Author(s):  
Xuandi Lai ◽  
Lishan Tan ◽  
Xiulong Deng ◽  
Jinbin Liu ◽  
Aiqing Li ◽  
...  

2012 ◽  
Vol 14 (6) ◽  
Author(s):  
Karolis Kazlauskas ◽  
Arūnas Miasojedovas ◽  
Darius Dobrovolskas ◽  
Eglė Arbačiauskienė ◽  
Vytautas Getautis ◽  
...  

2016 ◽  
Vol 40 (9) ◽  
pp. 7814-7820 ◽  
Author(s):  
Wei Shi ◽  
Shiyu Zhao ◽  
Yue Su ◽  
Yonghai Hui ◽  
Zhengfeng Xie

A barbituric acid–triphenylamine adduct displayed interesting aggregation-induced emission enhancement (AIEE) features in a THF–water co-solvent system and can act as a fluorescence turn-on probe for Hg2+.


Molecules ◽  
2020 ◽  
Vol 25 (23) ◽  
pp. 5732
Author(s):  
Hsing-Ju Wu ◽  
Cheng-Chung Chang

The major challenge in the fabrication of fluorescent silica nanoparticles (FSNs) based on dye-doped silica nanoparticles (DDSNs) is aggregation-caused fluorescence quenching. Here, we constructed an FSN based on a double emission enhancement (DEE) platform. A thio-reactive fluorescence turn-on molecule, N-butyl-4-(4-maleimidostyryl)-1,8-naphthalimide (CS), was bound to a silane coupling agent, (3-mercaptopropyl)-trimethoxysilane (MPTMS), and the product N-butyl-4-(3-(trimethoxysilyl-propylthio)styryl)-1,8-naphthalimide (CSP) was further used to fabricate a core–shell nanoparticle through the Stöber method. We concluded that the turn-on emission by CSP originated from the photoinduced electron transfer (PET) between the maleimide moiety and the CSP core scaffold, and the second emission enhancement was attributed to the aggregation-induced emission enhancement (AIEE) in CSP when encapsulated inside a core–shell nanoparticle. Thus, FSNs could be obtained through DEE based on a combination of PET and AIEE effects. Systematic investigations verified that the resulting FSNs showed the traditional solvent-independent and photostable optical properties. The results implied that the novel FSNs are suitable as biomarkers in living cells and function as fluorescent visualizing agents for intracellular imaging and drug carriers.


The Analyst ◽  
2020 ◽  
Vol 145 (21) ◽  
pp. 7009-7017
Author(s):  
Hai-Bo Wang ◽  
An-Li Mao ◽  
Tian Gan ◽  
Yan-Ming Liu

A turn-on fluorescence method has been designed for the determination of cellular GSH levels based on the controlled aggregation-induced emission enhancement of self-assembled CuNCs.


Sign in / Sign up

Export Citation Format

Share Document