scholarly journals Low-Cost Localized Surface Plasmon Resonance Biosensing Platform with a Response Enhancement for Protein Detection

Nanomaterials ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. 1019 ◽  
Author(s):  
Yun Liu ◽  
Ning Zhang ◽  
Ping Li ◽  
Li Yu ◽  
Shimeng Chen ◽  
...  

There are many potential applications for biosensors that can provide real-time analysis, such as environmental monitoring and disease prevention. In this study, we investigated a simple strategy for real-time protein detection, which had the advantages of affordability, fast response, portability, and ease of use. A robust quantification of protein interaction was achieved by combining capillary localized surface plasmon resonance (LSPR) sensors and complementary metal–oxide–semiconductor (CMOS) image sensors. Gold nanoparticles were modified on the inner wall of the capillary, which was used as a microfluidic channel and sensing surface. We functionalized one of the LSPR sensors using ligand bound to gold nanoparticle. Our proposed biosensing platform could be easily multiplexed to achieve high throughput screening of biomolecular interactions, and it has the potential for use in disposable sensors. Moreover, the sensing signal was enhanced by the extinction effect of gold nanoparticles. The experimental results showed that our device could achieve qualitative identification and quantitative measurement of transferrin and immunoglobulin G (IgG). As a field-portable and low-cost optical platform, the proposed LSPR biosensing device is broadly applicable to various protein binding tests via a similar self-assembly of organic ultrathin films.

The Analyst ◽  
2021 ◽  
Author(s):  
Jittrapun Soongsong ◽  
Jamras Lerdsri ◽  
Jaroon Jakmunee

A colorimetric aptasensor for chlorpyrifos detection utilizing localized surface plasmon resonance (LSPR) of gold nanoparticles (AuNPs) aggregation coupling with a specific aptamer and cationic polyethyleneimine (PEI) has been developed. The...


2021 ◽  
Author(s):  
Weixue Yang ◽  
Fei Li ◽  
Huali Liu ◽  
Zhen Li ◽  
Jiaqi Zhao ◽  
...  

A photo-assisted Li−Oxygen (Li−O2) battery with Au/SnO2 (ASO) hybrid nanotubes as cathode and photocatalyst has been prepared. The localized surface plasmon resonance (LSPR) excitation of gold nanoparticles (Au NPs) can...


2018 ◽  
Vol 54 (52) ◽  
pp. 7199-7202 ◽  
Author(s):  
Zhenli Qiu ◽  
Jian Shu ◽  
Dianping Tang

An in-depth exploration associated with localized surface plasmon resonance between g-C3N4/Bi2MoO6 and gold nanoparticles has been conducted for highly efficient photoelectrochemical aptasensors under ultraviolet and visible light irradiation.


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