scholarly journals A Novel Case of Bifacial Diplegia Variant of Guillain-Barré Syndrome Following Janssen COVID-19 Vaccination

2021 ◽  
Vol 13 (3) ◽  
pp. 404-409
Author(s):  
Apoorv Prasad ◽  
Gage Hurlburt ◽  
Sanjiti Podury ◽  
Medha Tandon ◽  
Seth Kingree ◽  
...  
Keyword(s):  
Rare Complication ◽  
Clinical Manifestations ◽  
Guillain Barre Syndrome ◽  
Demyelinating Disorder ◽  
Immune Mediated ◽  
Facial Diplegia ◽  
Guillain Barré Syndrome ◽  
Antecedent Infection ◽  
Guillain Barré ◽  
Csf Findings

Guillain-Barré syndrome (GBS) is an immune-mediated demyelinating disorder which attacks the peripheral nervous system. Antecedent infection or vaccine administration are known to precipitate the onset of this disorder. Its typical presentation leads to a symmetric, rapidly progressive, ascending paresis with associated sensory deficits and impaired reflexes. We present a rare case of a bi-facial diplegia variant of GBS, within four weeks of the COVID-19 vaccination. Due to its chronology, clinical manifestations, and cerebrospinal fluid (CSF) findings, we propose this case to be a rare complication of the COVID-19 vaccination.

Guillain–Barre syndrome: a rare complication of leptospirosis and scrub typhus co-infection

2019 ◽  
Vol 49 (3) ◽  
pp. 248-249 ◽  
Author(s):  
Nishant Dev ◽  
Rahul Kumar ◽  
Dilip Kumar
Keyword(s):  
Scrub Typhus ◽  
Case Reports ◽  
Rare Complication ◽  
Nerve Conduction Studies ◽  
Guillain Barre Syndrome ◽  
First Case ◽  
Immune Mediated ◽  
Guillain Barré Syndrome ◽  
Life Threatening ◽  
Guillain Barré

Guillain–Barré syndrome (GBS) is a potentially life-threatening immune-mediated acute inflammatory polyneuropathy associated with several antecedent infections. We report a 20-year-old man with GBS associated with concurrent leptospirosis and scrub typhus infection. GBS was confirmed with clinical examination and nerve conduction studies. There have been case reports of GBS in association with Leptospira and Orienta tsusugamushi separately. However, this may be the first case report of GBS associated with concurrent diseases.

scholarly journals Severe Headache, Paraesthesias, Facial Diplegia and Pleocytosis: A Misleading Presentation of Guillain-Barré Syndrome

2021 ◽  
Author(s):  
Mohamed Reda Belkhribchia ◽  
Abderrahim Chekabab ◽  
Yahya Naji ◽  
Latifa Hadrane ◽  
Soufiane Hassar ◽  
...  
Keyword(s):  
Clinical Manifestations ◽  
Severe Headache ◽  
Nerve Conduction Studies ◽  
Guillain Barre Syndrome ◽  
Sensory Disturbance ◽  
Limb Weakness ◽  
Motor Weakness ◽  
Facial Diplegia ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Guillain-Barré syndrome (GBS) is an acute inflammatory polyradiculoneuropathy. Progressive limb weakness, diminished/absent reflexes, sensory disturbance, and variable autonomic dysfunction are its core clinical manifestations. Bifacial weakness with paraesthesias (BFP) is a rare regional variant of GBS and is characterized by simultaneous facial diplegia, distal paraesthesias and minimal or no motor weakness. The association of headache with classic GBS has been rarely reported in the literature, and has not yet been described in the BFP variant. Here we report a misleading case of BFP variant associated with severe headache and mild pleocytosis. The repetition of nerve conduction studies (NCS) was extremely beneficial in this confusing case.

scholarly journals Guillain-Barré syndrome associated with COVID-19 infection: a case from the UK

2020 ◽  
Vol 13 (7) ◽  
pp. e236536 ◽  
Author(s):  
May Yung Tiet ◽  
Nazar AlShaikh
Keyword(s):  
Rare Complication ◽  
Guillain Barre Syndrome ◽  
Neurological Manifestations ◽  
Immune Mediated ◽  
Guillain Barré Syndrome ◽  
Guillain Barré ◽  
The Uk

Originating from Wuhan, China, COVID-19 has rapidly spread worldwide. Neurological manifestations are more commonly associated with severe COVID-19 infection. Guillain-Barré syndrome (GBS) is a rare immune-mediated postinfectious neuropathy. It has been reported as a possible rare complication of COVID-19. We report a case of GBS associated with COVID-19 in the UK.

scholarly journals The importance of thinking about Guillain-Barré syndrome during the COVID-19 pandemic: a case with pure dysautonomic presentation

2021 ◽  
Author(s):  
Erica Biassoni ◽  
Andrea Assini ◽  
Ilaria Gandoglia ◽  
Luana Benedetti ◽  
Silvia Boni ◽  
...  
Keyword(s):  
Nervous System ◽  
Electrophysiological Study ◽  
Clinical Manifestations ◽  
Neurological Complications ◽  
Guillain Barre Syndrome ◽  
System Disease ◽  
Immune Mediated ◽  
Inflammatory Mechanism ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

AbstractGuillain-Barré syndrome (GBS) is a peripheral nervous system disease caused by an immune-mediated inflammatory mechanism, usually triggered by a previous infectious process or vaccine; its typical presentation is a rapid and progressive bilateral limb hyposthenia, associated with sensory deficits and reduction or absence of osteotendinous reflexes. However, also autonomic nervous system can be involved with heart rate fluctuations, blood pressure instability, pupillary dysfunction, and urinary retention. Since the beginning of COVID-19 pandemic, GBS has been reported among neurological complications of SARS-CoV-2 infection, although etiopathological mechanisms still have to be clearly defined. We report the case of a 79-year-old man with multiple comorbidities, including diabetes, who was affected by SARS-CoV-2 interstitial pneumonia and developed dysautonomic symptoms after 10 days of hospitalization. A neurological evaluation was performed, and GBS was considered as a possible cause of the clinical manifestations. This hypothesis was confirmed by electrophysiological study and further supported, ex-juvantibus, by the satisfactory response to immunoglobulin treatment. In our opinion, this case of pure dysautonomic presentation of GBS in a SARS-CoV-2 positive patient is relevant because it suggests to consider GBS upon SARS-CoV-2 infection even if the symptoms have uncommon characteristics (e.g., pure vegetative manifestations) and if there are confounding factors which could lead to a misdiagnosis (e.g., old age, SARS-CoV-2 infection consequences and diabetes).

scholarly journals A Rare case of recurrent Guillain-Barré syndrome without albuminocytological dissociation

2018 ◽  
pp. bcr-2018-226572
Author(s):  
Anudeep Yelam ◽  
Elanagan Nagarajan ◽  
Raghav Govindarajan ◽  
Pradeep C Bollu
Keyword(s):  
Cerebrospinal Fluid ◽  
Rare Case ◽  
Guillain Barre Syndrome ◽  
Csf Analysis ◽  
Immune Mediated ◽  
Guillain Barré Syndrome ◽  
Sensory Disturbances ◽  
Guillain Barré ◽  
Csf Findings

Guillain-Barré syndrome (GBS) is an immune-mediated polyneuropathy, often preceded by an illness. It is a self-limiting illness in most of the cases, but recurrence is rare and can be seen in about 1%–6% of patients. GBS is characterised by progressive, symmetrical, proximal and distal weakness. Areflexia and sensory disturbances are also common. Patients with GBS usually have albuminocytological dissociation on cerebrospinal fluid (CSF) analysis. This is a case of a 69-year-old woman with recurrent GBS and normal CSF findings.

scholarly journals Isolated facial diplegia: A rare presentation of Guillain‐Barre syndrome

2021 ◽  
Vol 9 (7) ◽  
Author(s):  
Sundus Sardar ◽  
Sreethish Sasi ◽  
Suresh Menik Arachchige ◽  
Muhammad Zahid ◽  
Gayane Melikyan
Keyword(s):  
Guillain Barre Syndrome ◽  
Rare Presentation ◽  
Facial Diplegia ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Role of Gancyclovir and HAART Administration in the Treatment of a Rare Complication of HIV Disease: Cytomegalovirus-Associated Guillain-Barré Syndrome

2001 ◽  
Vol 13 (5) ◽  
pp. 575-577 ◽  
Author(s):  
L. Calza ◽  
R. Manfredi ◽  
G. Marinacci ◽  
E. Briganti ◽  
R. Giuliani S. Talo' ◽  
...  
Keyword(s):  
Rare Complication ◽  
Guillain Barre Syndrome ◽  
Hiv Disease ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

OVERLAP NEUROLOGICAL SYNDROMES ASSOCIATED WITH ANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE: CLINICAL OBSERVATION

2021 ◽  
Vol 100 (2) ◽  
pp. 284-287
Author(s):  
E.S. Druzhinina ◽  
◽  
R.T. Bembeeva ◽  
D.S. Druzhinin ◽  
U.M. Azizova ◽  
...  
Keyword(s):  
Glutamic Acid ◽  
Glutamic Acid Decarboxylase ◽  
Clinical Observation ◽  
Clinical Manifestations ◽  
Overlap Syndrome ◽  
Guillain Barre Syndrome ◽  
Acid Decarboxylase ◽  
Pediatric Practice ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

The article presents a description of an overlap syndrome, rare in pediatric practice, associated with antibodies to glutamic acid decarboxylase in a 4-year-old child, which was initially regarded as a variant of Guillain–Barré syndrome due to the similarity of clinical manifestations.

scholarly journals Reworsening of Recurrent Guillain-Barré Syndrome Triggered by COVID-19 Infection

2021 ◽  
Vol 15 (1) ◽  
pp. 48-51
Author(s):  
Gian Luca Vita ◽  
Carmen Terranova ◽  
Maria Sframeli ◽  
Antonio Toscano ◽  
Giuseppe Vita
Keyword(s):  
Viral Infection ◽  
Neurological Diseases ◽  
Intravenous Immunoglobulins ◽  
Guillain Barre Syndrome ◽  
Case Presentation ◽  
Appropriate Treatment ◽  
Immune Mediated ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Introduction: Guillain-Barré Syndrome (GBS) is an acute, immune-mediated, generalized polyradiculoneuropathy often triggered by a bacterial or viral infection, vaccination, or surgery. During the SARS-CoV-2 pandemic, some patients were reported with GBS associated COVID-19 infection. Case Presentation: We report, herein, a patient who had a recurrent GBS after forty years. Intravenous immunoglobulins (IVIg) induced improvement, but her condition worsened suddenly after twenty days, coinciding with a COVID-19 infection. A second IVIg cycle was administered, and she improved again. Conclusion: The take-home message is that in the current pandemic, any re-worsening or lack of improvement after appropriate treatment of GBS or possibly other autoimmune neurological diseases must be checked to determine if it is related to COVID-19 infection.

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