scholarly journals Personalized Nutrition Approach in Food Allergy: Is It Prime Time Yet?

Nutrients ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 359 ◽  
Author(s):  
Enza D’Auria ◽  
Mariette Abrahams ◽  
GianVincenzo Zuccotti ◽  
Carina Venter

The prevalence of food allergy appears to be steadily increasing in infants and young children. One of the major challenges of modern clinical nutrition is the implementation of individualized nutritional recommendations. The management of food allergy (FA) has seen major changes in recent years. While strict allergen avoidance is still the key treatment principle, it is increasingly clear that the avoidance diet should be tailored according to the patient FA phenotype. Furthermore, new insights into the gut microbiome and immune system explain the rising interest in tolerance induction and immunomodulation by microbiota-targeted dietary intervention. This review article focuses on the nutritional management of IgE mediated food allergy, mainly focusing on different aspects of the avoidance diet. A personalized approach to managing the food allergic individual is becoming more feasible as we are learning more about diagnostic modalities and allergic phenotypes. However, some unmet needs should be addressed to fully attain this goal.

2021 ◽  
Vol 3 (2) ◽  
pp. 080-086
Author(s):  
Melike YILDIZ ◽  
Gülcan ARUSOĞLU

Food allergy is a reaction mediated by immunological mechanisms that cause various symptoms in susceptible individuals while harmless in individuals who are not sensitive to the specific allergen. The reactions that take place are divided into three: IgE-mediated reactions, non-IgE-mediated reactions, and mixed-type reactions. While many types of food have the potential to cause allergen reactions, fewer foods are responsible for the most clinically severe reactions and for the majority of reported cases. Food allergy, which is increasingly common worldwide, is becoming an important public health problem. Although there are no clear epidemiological data, the prevalence of food allergy varies between 6-10% in preschool children and decreases to 2-5% in adulthood. Food allergy has long been recognized as a pediatric disease, as most cases tend to begin in childhood and disappear with growth. There is increasing evidence to support the role of early administration of potential food allergens to prevent food allergy. The management process of food allergy cases includes plans and innovative treatment strategies aimed at a personalized approach.


2013 ◽  
Vol 3 (S3) ◽  
Author(s):  
C Arêde ◽  
A Cabral ◽  
S Piedade ◽  
M Morais-Almeida

2020 ◽  
Vol 2 (1) ◽  
pp. 7-10
Author(s):  
Wayne G. Shreffler

The pathophysiology of immunoglobulin E (IgE) mediated food allergy has been understood on a superficial level for several decades. Surveillance by dendritic cells for exogenous antigens leads to a high-affinity IgE response that arms effector cells (sensitization), such that subsequent exposures can trigger a type 1 hypersensitivity recall response. However, merely scratching the surface, whether confronting unmet needs in a clinical setting or probing the basic immunology of allergic immunity, quickly reveals the many unmet fundamental questions that lie there. This review article focused on the following such questions. Why are common allergens common? How does sensitization most often occur? How is IgE maintained over long time periods, even in the apparent absence of exposure? What distinguishes sensitization from clinical allergy? Can we stratify risk (i.e., sensitivity and severity)? What distinguishes the pathophysiology of non‐IgE-mediated allergy when so much of it seems to overlap?


Alergologia ◽  
2019 ◽  
Vol 4 (3) ◽  
pp. 154
Author(s):  
G.M. Feketea ◽  
Corina Bocșan
Keyword(s):  

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