scholarly journals Cyclodextrin Multicomponent Complexes: Pharmaceutical Applications

Pharmaceutics ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1099
Author(s):  
Virginia Aiassa ◽  
Claudia Garnero ◽  
Marcela R. Longhi ◽  
Ariana Zoppi
Keyword(s):  
Amino Acids ◽  
Pharmaceutical Industry ◽  
Drug Effects ◽  
Water Soluble ◽  
Therapeutic Drug ◽  
Water Soluble Polymers ◽  
Soluble Polymers ◽  
Pharmaceutical Applications ◽  
Auxiliary Substance ◽  
Acids And Bases

Cyclodextrins (CDs) are naturally available water-soluble cyclic oligosaccharides widely used as carriers in the pharmaceutical industry for their ability to modulate several properties of drugs through the formation of drug–CD complexes. The addition of an auxiliary substance when forming multicomponent complexes is an adequate strategy to enhance complexation efficiency and to facilitate the therapeutic applicability of different drugs. This review discusses multicomponent complexation using amino acids; organic acids and bases; and water-soluble polymers as auxiliary excipients. Special attention is given to improved properties by including information on the solubility, dissolution, permeation, stability and bioavailability of several relevant drugs. In addition, the use of multicomponent CD complexes to enhance therapeutic drug effects is summarized.

scholarly journals High-temperature resistant water-soluble polymers derived from exotic amino acids

RSC Advances ◽  
2020 ◽  
Vol 10 (62) ◽  
pp. 38069-38074
Author(s):  
Sumant Dwivedi ◽  
Aniruddha Nag ◽  
Shigeki Sakamoto ◽  
Yasuyoshi Funahashi ◽  
Toyohiro Harimoto ◽  
...  
Keyword(s):  
Amino Acids ◽  
High Temperature ◽  
High Performance ◽  
Water Soluble ◽  
Water Soluble Polymers ◽  
Soluble Polymers ◽  
Wide Range ◽  
Soluble Polyimide ◽  
Engineering Materials

High-performance water-soluble polymers have a wide range of applications from engineering materials to biomedical plastics. This article discusses the synthesis of water-soluble polyimide from bio-based monomers.

scholarly journals Application of Water-Soluble Polymers for Extraction Separation of Amino Acids of Various Structures

2015 ◽  
Vol 12 (12) ◽  
pp. 1032-1041
Author(s):  
Nadezhda Yakovlevna Mokshina ◽  
Dmitry Vladimirovich Bykovskiy ◽  
Gennadiy Valentinovich Shatalov ◽  
Oksana Anatolievna Pakhomova
Keyword(s):  
Amino Acids ◽  
Water Soluble ◽  
Water Soluble Polymers ◽  
Soluble Polymers ◽  
Extraction Separation

scholarly journals Water Soluble Polymers for Pharmaceutical Applications

Polymers ◽  
2011 ◽  
Vol 3 (4) ◽  
pp. 1972-2009 ◽  
Author(s):  
Veeran Gowda Kadajji ◽  
Guru V. Betageri
Keyword(s):  
Water Soluble ◽  
Water Soluble Polymers ◽  
Soluble Polymers ◽  
Pharmaceutical Applications

New quenching media based on water-soluble polymers

1981 ◽  
Vol 23 (2) ◽  
pp. 104-106 ◽  
Author(s):  
A. V. Tolstousov ◽  
O. A. Bannykh
Keyword(s):  
Water Soluble ◽  
Water Soluble Polymers ◽  
Soluble Polymers ◽  
Quenching Media

scholarly journals SANS quantification of bound water in water-soluble polymers across multiple concentration regimes

Soft Matter ◽  
2021 ◽  
Author(s):  
Helen Yao ◽  
Bradley D. Olsen
Keyword(s):  
Neutron Scattering ◽  
Small Angle ◽  
Small Angle Neutron Scattering ◽  
Bound Water ◽  
Water Soluble ◽  
Wide Concentration Range ◽  
Water Molecules ◽  
Water Soluble Polymers ◽  
Soluble Polymers

Small-angle neutron scattering is used to measure the number of bound water molecules associating with three polymers over a wide concentration range. Different fitting workflows are evaluated and recommended depending on the concentration regime.

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