Stephan Oroszlan and the Proteolytic Processing of Retroviral Proteins: Following A Pro
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Steve Oroszlan determined the sequences at the ends of virion proteins for a number of different retroviruses. This work led to the insight that the amino-terminal amino acid of the mature viral CA protein is always proline. In this remembrance, we review Steve’s work that led to this insight and show how that insight was a necessary precursor to the work we have done in the subsequent years exploring the cleavage rate determinants of viral protease processing sites and the multiple roles the amino-terminal proline of CA plays after protease cleavage liberates it from its position in a protease processing site.
1991 ◽
Vol 266
(11)
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pp. 7044-7050
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1989 ◽
Vol 106
(4)
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pp. 589-592
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1989 ◽
Vol 50
(1)
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pp. 113-120
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1996 ◽
Vol 37
(5)
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pp. 612-620
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