Transcranial magnetic stimulation in neurorehabilitation: experience and prospects

2021 ◽  
pp. 7-17
Author(s):  
Vladislav Borisovich Voitenkov ◽  
J. Málly ◽  
I. V. Cherkashina ◽  
N. V. Skripchenko . ◽  
E. V. Ekusheva ◽  
...  

Diagnostic transcranial magnetic stimulation (TMS) is a valuable neurophysiological technique. The use of TMS has fundamentally changed the therapy and diagnosis of nervous diseases, introducing the possibility of direct assessment of conduction along the motor pathway in the central region, neuroplasticity, the ratio of central inhibition and excitation, and the effect on neuroplasticity and neurogenesis. The technique is safe, has a low cost and there is no need to purchase expensive consumables, it is applicable for a wide range of diseases in both adult and pediatric practice. The issues of the TMS use in CVA, depression, cerebral palsy and neurodegenerative diseases (amyotrophic lateral sclerosis, parkinsonism) have been studied to the greatest extent. When carrying out TMS in children, it should be borne in mind that signs of incomplete myelination of the motor pathways, which are normally observed, may look like pathological changes (demyelination or axonal disorders). The basic principles of TMS in both adults and children have been established and known, and the age norms have been determined, which makes it possible to widely implement this technique in applied neurophysiological practice. In the rehabilitation process, TMS can be used as a tool for personalizing and monitoring the effectiveness of rehabilitation treatment.

Physiology ◽  
2001 ◽  
Vol 16 (6) ◽  
pp. 297-302 ◽  
Author(s):  
Kai M. Rösler

Transcranial magnetic stimulation allows the painless activation of cortical motor neurons and elicits responses in a wide range of muscles, termed “motor-evoked potentials.” Since its introduction in 1985, the technique has evolved as one of the most fruitful recent contributions to clinical neurophysiology.


2011 ◽  
Vol 122 (5) ◽  
pp. 975-983 ◽  
Author(s):  
Petro Julkunen ◽  
Jarmo Ruohonen ◽  
Saara Sääskilahti ◽  
Laura Säisänen ◽  
Jari Karhu

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Daniele Gatti ◽  
Floris Van Vugt ◽  
Tomaso Vecchi

Abstract Mounting evidence suggests that the cerebellum, a structure previously linked to motor function, is also involved in a wide range of non-motor processes. It has been proposed that the cerebellum performs the same computational processes in both motor and non-motor domains. Within motor functions, the cerebellum is involved in the integration of signals from multiple systems. Here we hypothesized that cerebellum may be involved in integration within semantic memory as well. Specifically, understanding a noun-adjective combination (e.g. red apple) requires combining the meaning of the adjective (red) with the meaning of the noun (apple). In two experiments, participants were asked to judge whether noun-adjective word-pairs were semantically related (e.g., red apple) or not (e.g., lucky milk) while online transcranial magnetic stimulation (TMS) was administered over the right cerebellum or over a control site (vertex in Experiment 1 and visual cortex in Experiment 2). Cerebellar TMS caused a decrease in participants’ accuracy for related word-pairs while accuracy for unrelated stimuli was not affected. A third experiment using a control task where subjects compared pairs of random letters showed no effect of TMS. Taken together these results indicate that the right cerebellum is involved specifically in the processing of semantically related stimuli. These results are consistent with theories that proposed the existence of a unified cerebellar function within motor and non-motor domains, as well with recent perspectives about cerebellar involvement in semantic memory and predictive cognition.


1999 ◽  
Vol 110 (3) ◽  
pp. 445-448 ◽  
Author(s):  
Masahito Kobayashi ◽  
Takayuki Ohira ◽  
Masato Ochiai ◽  
Ban Mihara ◽  
Takeshi Kawase

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