scholarly journals Modern Approach to the Diagnosis and Treatment of Idiopathic Oligoasthenoteratozoospermia

Author(s):  
D.G. Pochernikov ◽  
◽  
V.V. Getman
GYNECOLOGY ◽  
2018 ◽  
Vol 20 (6) ◽  
pp. 35-41
Author(s):  
T Yu Pestrikova ◽  
I V Yurasov ◽  
E A Yurasova

Medical, social and economic relevance of inflammatory diseases of the woman's reproductive organs requires a very careful attitude to the diagnosis and treatment of this pathology. The number of patients with genital infections and inflammatory diseases of the pelvic organs can takes the first place in structure of gynecological morbidity, and is 60.4-65.0%, and this fact is not unique to Russia, but all over the world. Incidence rate of inflammatory diseases of the pelvic organs in the first decade of the twenty-first century is increased at 1.4 times in patients who are from 18 to 24 years old and at 1.8 times in patients aged 25-29 years. At the same time, the cost of diagnosis and treatment has increased, reaching 50-60% of the total cost of providing gynecological care for population. The inflammatory diseases of pelvic organs are a collective concept. It includes of various nosological forms. There are numerous contradictions in the views on diagnostic approaches and treatment tactics, the nature of screening and control over the long-term results of treatment, the etiological and pathogenetic significance of various microorganisms found in the genital tract in patients with inflammatory diseases of the pelvic organs. Currently, there are many opinions among specialists about diagnostic approaches and treatment tactics, the type of screening and monitoring the long-term results of treatment, the etiological and pathogenetic role of various microorganisms which can be found in the genital tract in patients with inflammatory diseases. This review presents the results of a modern approach to the diagnosis, management and rehabilitation of patients with inflammatory diseases of the pelvic organs.


2021 ◽  
pp. 56-75
Author(s):  
V.Yu. Martyniuk ◽  
◽  
T.K. Znamenska ◽  
V.B. Shveikina ◽  
V.A. Galagan ◽  
...  

The article is devoted to the topical problem of neonatology and pediatric neurology — the diagnosis and treatment of seizures in newborns and young children. The work presents an algorithm for the diagnosis and treatment of epileptic seizures in children. It is indicated that the therapeutic effect of most antiepileptic drugs consists of modulation of voltage-gated and ligand-gated channels of membranes of neurons of the cerebral cortex, enhancement of inhibitory synaptic transmission or inhibition of activating synaptic transmission. The issues of the pharmacokinetics and pharmacodynamics of antiepileptic drugs are considered, taking into account the age characteristics of the child's body, in particular, newborns and early age children. The problems of drug interaction were discussed. The properties of individual antiepileptic drugs, which are used in newborns and young children, are considered. Emphasized are «polar» differences in the work of phenobarbital, which depend on the stage of epileptogenesis, namely: suppression of epileptiform activity at the early stage of epileptogenesis and its enhancement in the already formed epileptic focus (epileptic system). The literature data on the differentiated treatment of certain epileptic syndromes are presented. The issues on the prospects for the treatment of genetically determined diseases, which are accompanied by seizures associated with metabolic disorders, are considered. The modern high-tech methods of treatment of these diseases are noted. The role of diet therapy, co-factor therapy in the treatment of hereditary metabolic disorders, in particular, the ketogenic diet as a method of alternative treatment for drug-resistant epilepsy in children, is shown. No conflict of interest was declared by the authors. Key words: newborn, epilepsy, epileptic encephalopathy, treatment, antiepileptic drugs, review.


Author(s):  
Vladimir Orobets ◽  
Sergey Larionov ◽  
Ludmila Kashkovskaya ◽  
Daria Korotova

2021 ◽  
Vol 21 (2) ◽  
pp. 65-75
Author(s):  
Anna Barczak ◽  
Tomasz Gabryelewicz

The diagnosis of dementia and further management of patients are based on the latest recommendations developed by European and global organisations dealing with the diagnosis and standards of treatment of neurodegenerative diseases. Using useful and practical diagnostic methods, as well as the results of the latest additional tests and differential tools, a modern approach allows for a relatively quick diagnosis and implementation of recommended treatment. In addition to dementia in the course of Alzheimer’s disease, the paper presents recommendations for the diagnosis and treatment of other diseases including vascular dementia, dementia with Lewy bodies, dementia in Parkinson’s disease, frontotemporal dementia, and atypical parkinsonisms. Particular attention is given to the diagnosis of mild cognitive impairment due to Alzheimer’s disease and the possibilities of diagnosis and treatment of this phase, not only in a specialised medical practice. The article discusses the principles of procognitive pharmacological management in dementia and in the case of neuropsychiatric problems: psychotic, behavioural, and mood disorders. The importance of non-pharmacological management, primarily diet and cognitive stimulation, is also highlighted. Patient care requires close cooperation between the doctor and the caregiver, who is as important as the patient, and satisfying the caregiver’s needs is a guarantee of better care for the patient. Specifically, caregivers should be supported in handling their medical, legal, and psychological problems resulting from the burden of caring for the patient.


Author(s):  
S.V. Pozyabin ◽  
◽  
Yu.I. Filippov ◽  
K.I. Sharykina ◽  
◽  
...  

Diagnosis and treatment of aseptic and purulent tarsal bursitis in cattle remains an important task for veterinarians. Conventional diagnostic methods did not allow detecting animals with this pathology at early stages, which led to a deterioration in the clinical condition of the animal, loss of productivity and culling.


2020 ◽  
Vol 5 (1) ◽  
pp. 32-35
Author(s):  
Ludmila A. Baryshevskaya ◽  
Pavel M. Zelter ◽  
Inna O. Chernyshenko ◽  
Olesya V. Zelyova ◽  
Evgeniya V. Koldova

Objectives - to present a modern approach to the diagnosis and treatment of chronic suppurative otitis media with cholesteatoma, which led to a defect in the upper wall of the temporal bone pyramid. The case presented emphasizes the importance of timely diagnosis and treatment of this disease. Material and methods. Complaints, anamnesis, data from objective examination, additional methods of examination (high-frequency tone threshold audiometry multispiral computed tomography of temporal bones, diffusion-weighted magnetic resonance imaging of the brain). Conclusion. An innovative integrated approach, using radiological methods for studying the temporal bone (temporal bone multispiral CT, diffusion-weighted MRI of the brain), allows to diagnose cholesteatoma, the presence of bone-destructive changes in the structures of the middle and inner ear, as well as to determine the boundaries of the formed structure, which is important for planning modern surgical intervention.


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