Cosmetics � Sun protection test methods � In vivo determination of the sun protection factor (SPF)

2020 ◽  
2017 ◽  
Vol 11 (1) ◽  
pp. e201600257 ◽  
Author(s):  
Carina Reble ◽  
Ingo Gersonde ◽  
Sabine Schanzer ◽  
Martina C. Meinke ◽  
Jürgen Helfmann ◽  
...  

Cosmetics ◽  
2020 ◽  
Vol 7 (1) ◽  
pp. 16 ◽  
Author(s):  
Muhammed Majeed ◽  
Shaheen Majeed ◽  
Renuka Jain ◽  
Lakshmi Mundkur ◽  
H. R. Rajalakshmi ◽  
...  

Ultraviolet (UV) rays and its harmful effects have always been a concern to skin health. Sunscreen and sunblock prevent the harmful effects of UV radiation on the skin. Sun Protection Factor (SPF) is an indication of the sun-protective capacity of an ingredient. There is an ever increasing interest in the cosmetic industry for developing novel functional ingredients from natural sources. The purpose of this study was to determine in-vitro and in vivo SPF of natural 90% pterostilbene extracted from the dried heartwood of Pterocarpus marsupium (Indian Kino). The SPF of purified pterostilbene and a formulation containing 0.4% pterostilbene was determined In Vitro using a UV spectrophotometer. Pterostilbene had an SPF of 21.73 ± 0.06, while the cream formulation had an SPF of 8.84 ± 0.01. The in vivo SPF of the 0.4% pterostilbene cream in humans was found to be 6.2 ± 1.30. Primary skin irritation tests in human subjects showed the formulation was safe and had no irritation potential. Pterostilbene was also found to have significant antioxidant activity as determined by free radical scavenging assays in vitro. These results suggest that natural pterostilbene is an antioxidant and shows SPF value both in-vitro and in the human clinical study and thus could be used as an ingredient in topical sun-protective formulations.


2019 ◽  
Vol 4 (2) ◽  
pp. 26-31
Author(s):  
Rabiatul Adawiyah

The sunscreens or Sun Protecting Agent is the materials protecting the skin from the exposure to ultraviolet (UV) rays. Amount of Sun Protection Factor shows how many times the subject skin protection can be multiplied under the sun rays without erythema occurs. Kalakai contains some bio-active substance like phenol, flavonoid, alkaloid and terpenoid family which are proven as a very effective antioxidant. The purpose of this research was to determine the concentration of ethanol extract of kalakai root which has the potential as a sunscreen based on the Sun Protection Factor (SPF) parameter. Determination of SPF amount was carried out in vitro by UV-VIS spectrophotometer at a concentration of 50 ppm, 100 ppm, 150 ppm, 200 ppm, 250 ppm, 300 ppm, and 350 ppm with a wavelength of 290-320 nm. The result showed that kalakai root ethanol extract indicated potential as a sunscreen at a concentration of 300 ppm and 350 ppm obtained SPF values respectively 11 and 14 classified as sunscreens with extreme ability levels.


2020 ◽  
Vol 11 (2) ◽  
Author(s):  
M.-T. Sheu ◽  
C.-W. Lin ◽  
M.-C. Huang ◽  
C.-H. Shen ◽  
H.-O. Ho

Sign in / Sign up

Export Citation Format

Share Document