scholarly journals A Randomized Study to Determine the Sun Protection Factor of Natural Pterostilbene from Pterocarpus Marsupium

Cosmetics ◽  
2020 ◽  
Vol 7 (1) ◽  
pp. 16 ◽  
Author(s):  
Muhammed Majeed ◽  
Shaheen Majeed ◽  
Renuka Jain ◽  
Lakshmi Mundkur ◽  
H. R. Rajalakshmi ◽  
...  

Ultraviolet (UV) rays and its harmful effects have always been a concern to skin health. Sunscreen and sunblock prevent the harmful effects of UV radiation on the skin. Sun Protection Factor (SPF) is an indication of the sun-protective capacity of an ingredient. There is an ever increasing interest in the cosmetic industry for developing novel functional ingredients from natural sources. The purpose of this study was to determine in-vitro and in vivo SPF of natural 90% pterostilbene extracted from the dried heartwood of Pterocarpus marsupium (Indian Kino). The SPF of purified pterostilbene and a formulation containing 0.4% pterostilbene was determined In Vitro using a UV spectrophotometer. Pterostilbene had an SPF of 21.73 ± 0.06, while the cream formulation had an SPF of 8.84 ± 0.01. The in vivo SPF of the 0.4% pterostilbene cream in humans was found to be 6.2 ± 1.30. Primary skin irritation tests in human subjects showed the formulation was safe and had no irritation potential. Pterostilbene was also found to have significant antioxidant activity as determined by free radical scavenging assays in vitro. These results suggest that natural pterostilbene is an antioxidant and shows SPF value both in-vitro and in the human clinical study and thus could be used as an ingredient in topical sun-protective formulations.

2020 ◽  
Vol 11 (2) ◽  
Author(s):  
M.-T. Sheu ◽  
C.-W. Lin ◽  
M.-C. Huang ◽  
C.-H. Shen ◽  
H.-O. Ho

Author(s):  
Pahol Sansomchai ◽  
◽  
Kanlaya Jumpatong ◽  
Chaipat Lapinee ◽  
Kanchana Utchariyajit ◽  
...  

The ultimate aim of this study was to evaluate antioxidant activities using DPPH and ABTS assay and antioxidant substances of Melientha suavis Pierre (Melientha) extracts with ethanol (EtOH) and subsequent partition with hexane, dichloromethane (CH2Cl2), ethyl acetate (EtOAc) and distilled water (W). The Melientha extract was assessed the sunscreen activities by sun protection factor which was compared with octyldimethyl PABA. Additionally, the stability test of Melientha extracts added in the cosmetic base-formula was investigated. The sun protection substances of Melientha extracts were determined by GC-MS analysis. Among the extract and fractions, the ethanolic extract showed the highest activities. The IC50 of Melientha extract to free radical scavenging determined by DPPH assay and ABTS assay were 53.20 ± 7.37 μg/ml and 64.17 ± 5.76 μg/ml, respectively. The total phenolic compound of ethanol extract was 149.87 ± 2.72 mg GE/g of ext and total flavonoid content was 51.60 ± 4.12 mg CE/g of ext. The sun protection factor (SPF) of ethanol extract was 26.61 ± 0.10. Cinamate and its derivative which were claim as sunscreen substance was found by GC-MS analysis of Melientha ethanol extract.


2012 ◽  
Vol 101 (2) ◽  
pp. 726-732 ◽  
Author(s):  
Leonardo R. de Paula ◽  
André L.A. Parussulo ◽  
Koiti Araki ◽  
Henrique E. Toma

2017 ◽  
Vol 2 (1) ◽  
Author(s):  
Youstiana Dwi Rusita ◽  
Indarto A.S

Abstract : SPF, Kayumanis, Pomegranate, Lotions. The Sun produces ultraviolet radiation that causes damage to the skin texture, premature aging, burning skinreactions and skin cancer in exposed skin in a long period. One of the ways to protect skin from UV radiation use sunscreen lotions. Stem bark of cinnamon (Cinnamomun burmani) and pomegranate peel (Punica granatum) is known as an antioxidant activity and have a compound that is potentially as sunscreens. This research aims to know the activity of sunscreen with an SPF value of sunscreen lotions of pomegranate peel and cinnamon extract and the warming rays of the Sun and closed space. The determination of the value of the sun protection factor is done with methods of in vitro in Mansur using spectrophotometer UV-Vis. SPF Value calculated based on the Absorbance at a wavelength of 290-320 nm. The result is a non parametric Test is analyzed using MannWhitney test. Results of organoleptic the colored is yellow brown, like to emultion and shaped the distinctive, smell of cinnamon, less homogeneous, showed the value of pH5.63, dispersive power 6 cm, adhesion 1.75 seconds and viscosity 5,500 cps. Preparations that are exposed in the Sunlight showed the value of SPF 20.146 hereaspreparations stored in enclosed space showed the value of SPF 26.398. The results of statistical tests indicate that there is no difference between the SPF on reparations that are exposed to sunlight and in a closed space with alpha value > 0.05.


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