Faculty Opinions recommendation of Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors.

2001 ◽  
Author(s):  
Stanley Froehner
Keyword(s):  
Crystal Structure ◽  
Ligand Binding ◽  
Nicotinic Receptors ◽  
Binding Protein ◽  
Binding Domain ◽  
Ligand Binding Domain

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

Nature ◽  
2001 ◽  
Vol 411 (6835) ◽  
pp. 269-276 ◽  
Author(s):  
KatjuS̆a Brejc ◽  
Willem J. van Dijk ◽  
Remco V. Klaassen ◽  
Mascha Schuurmans ◽  
John van der Oost ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Ligand Binding ◽  
Nicotinic Receptors ◽  
Binding Protein ◽  
Binding Domain ◽  
Ligand Binding Domain

scholarly journals Crystal Structure of the Mp1p Ligand Binding Domain 2 Reveals Its Function as a Fatty Acid-binding Protein

2010 ◽  
Vol 285 (12) ◽  
pp. 9211-9220 ◽  
Author(s):  
Shuang Liao ◽  
Edward T. K. Tung ◽  
Wei Zheng ◽  
Ken Chong ◽  
Yuanyuan Xu ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Fatty Acid ◽  
Ligand Binding ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Binding Domain ◽  
Ligand Binding Domain ◽  
Fatty Acid Binding ◽  
Acid Binding Protein

Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor

Nature ◽  
10.1038/43705 ◽  
1999 ◽  
Vol 401 (6749) ◽  
pp. 184-188 ◽  
Author(s):  
Christian Wiesmann ◽  
Mark H. Ultsch ◽  
Steven H. Bass ◽  
Abraham M. de Vos
Keyword(s):  
Crystal Structure ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Ligand Binding ◽  
Binding Domain ◽  
Ligand Binding Domain ◽  
Trka Receptor ◽  
Nerve Growth

scholarly journals Inter-residue coupling contributes to high-affinity subtype-selective binding of α-bungarotoxin to nicotinic receptors

2013 ◽  
Vol 454 (2) ◽  
pp. 311-321 ◽  
Author(s):  
Steven M. Sine ◽  
Sun Huang ◽  
Shu-Xing Li ◽  
Corrie J. B. daCosta ◽  
Lin Chen
Keyword(s):  
Crystal Structure ◽  
Ligand Binding ◽  
Nicotinic Receptors ◽  
Radioligand Binding ◽  
Binding Domain ◽  
Tyrosine Residue ◽  
Selective Binding ◽  
Conserved Residues ◽  
High Affinity ◽  
Subtype Selective

On the basis of the crystal structure of a pentameric α7 ligand-binding domain chimaera with bound α-bungarotoxin, mutagenesis and radioligand-binding measurements show that high-affinity target-selective binding depends on interactions between a single conserved tyrosine residue in α7 and nearby conserved and non-conserved residues.

scholarly journals Crystal structure of the ligand-binding domain of the promiscuous EphA4 receptor reveals two distinct conformations

2010 ◽  
Vol 399 (4) ◽  
pp. 555-559 ◽  
Author(s):  
Nikhil Singla ◽  
Yehuda Goldgur ◽  
Kai Xu ◽  
Sari Paavilainen ◽  
Dimitar B. Nikolov ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Ligand Binding ◽  
Binding Domain ◽  
Ligand Binding Domain

How well can molecular modelling predict the crystal structure: the case of the ligand-binding domain of glutamate receptors

2000 ◽  
Vol 21 (3) ◽  
pp. 87-92 ◽  
Author(s):  
Yoav Paas ◽  
Anne Devillers-Thiéry ◽  
Vivian I Teichberg ◽  
Jean-Pierre Changeux ◽  
Miriam Eisenstein
Keyword(s):  
Crystal Structure ◽  
Ligand Binding ◽  
Glutamate Receptors ◽  
Molecular Modelling ◽  
Binding Domain ◽  
Ligand Binding Domain
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